Induction of labor and nulliparity: a nation ‐wide clinical practice pilot evaluation
AbstractIntroductionInduction of labor has become an increasingly common obstetric procedure. However, in nulliparous women or women with a previous cesarean section, induction of labor can pose a clinical challenge. Despite an overall expansion of medical indications for labor induction, there is little international consensus regarding the criteria for induction of labor, or for the recommended methods among nulliparous women. In this light, we assessed variations in the practice of induction of labor among 21 birth units in a nation ‐wide cohort of women with no prior vaginal birth.Material and methodsWe carried out a...
Source: Acta Obstetricia et Gynecologica Scandinavica - July 1, 2020 Category: OBGYN Authors: Ingvil Krarup S ørbye, Kevin Sunde Oppegaard, Andrew Weeks, Kjersti Marsdal, Anne Flem Jacobsen Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Nursing Support During Latent Phase Labor: A Scoping Review
Purpose: The purpose of this scoping review was to synthesize the literature on nursing support during the latent phase of the first stage of labor. In 2014, the definition of the beginning of active labor changed from 4 centimeters (cm) to 6 cm cervical dilation. More women may have an induction of labor based on results of recent research showing no causal increase in risk of cesarean birth with elective induction of labor for low-risk nulliparous women. Therefore, in-hospital latent phase labor may be longer, increasing the need for nursing support. Design: Scoping review of the literature from 2009 to present. Me...
Source: MCN: The American Journal of Maternal Child Nursing - June 30, 2020 Category: Nursing Tags: Feature: CE Connection Source Type: research

Inpatient versus outpatient induction of labour: a systematic review and meta-analysis
This study aims to systematically review published data fr... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - June 30, 2020 Category: OBGYN Authors: Susan Dong, Maria Khan, Farahnosh Hashimi, Caroline Chamy and Rohan D ’Souza Tags: Research article Source Type: research

Organ-On-Chip Technology: The Future of Feto-Maternal Interface Research?
The placenta and fetal membrane act as a protective barrier throughout pregnancy while maintaining communication and nutrient exchange between the baby and the mother. Disruption of this barrier leads to various pregnancy complications, including preterm birth, which can have lasting negative consequences. Thus, understanding the role of the feto-maternal interface during pregnancy and parturition is vital to advancing basic and clinical research in the field of obstetrics. However, human subject studies are inherently difficult, and appropriate animal models are lacking. Due to these challenges, in vitro cell culture-base...
Source: Frontiers in Physiology - June 30, 2020 Category: Physiology Source Type: research

Labor and Delivery Outcomes with the Sequential Use of Misoprostol Followed by Cervical Foley Catheter
Am J Perinatol DOI: 10.1055/s-0040-1713818 Objective Studies demonstrate shorter time to delivery with concurrent use of misoprostol and cervical Foley catheter. However, concurrent placement may not be feasible. If misoprostol is used to start an induction, little is known regarding the benefit of sequentially using Foley catheter. We examine obstetrical outcomes in women with Foley catheter placed after misoprostol compared with those only requiring misoprostol. Study design Retrospective cohort study of singleton pregnancies, intact membranes, and an unfavorable cervix (Bishop score of ≤6 and dilation...
Source: American Journal of Perinatology - June 28, 2020 Category: Perinatology & Neonatology Authors: Hopkins, Maeve K. Hamm, Rebecca F. Srinivas, Sindhu K. Levine, Lisa D. Tags: Original Article Source Type: research

Life stressors, hypertensive disorders of pregnancy, and preterm birth.
Authors: Morgan N, Christensen K, Skedros G, Kim S, Schliep K Abstract Background: Stress-induced pregnancy complications are thought to represent a significant cause of maternal morbidity and mortality; little is known regarding types of stress most predictive of adverse outcomes.Methods: We used Utah PRAMs 2012-2014 data to evaluate links between preconception life stressors and prevalence of hypertensive disorders of pregnancy (HDP) and pre-term labor (PTB) (births
Source: Journal of Psychosomatic Obstetrics and Gynaecology - June 24, 2020 Category: OBGYN Tags: J Psychosom Obstet Gynaecol Source Type: research

IJERPH, Vol. 17, Pages 4553: Progress in Occupational Asthma
islava Nedeva Occupational asthma (OA) represents one of the major public health problems due to its high prevalence, important social and economic burden. The aim of this review is to summarize current data about clinical phenotypes, biomarkers, diagnosis and management of OA, a subtype of work-related asthma. Most studies have identified two phenotypes of OA. One is sensitizer-induced asthma, occuring after a latency period and caused by hypersensitivity to high- or low-molecular weight agents. The other is irritant-induced asthma, which can occur after one or more exposures to high concentrations of irritants withou...
Source: International Journal of Environmental Research and Public Health - June 24, 2020 Category: Environmental Health Authors: Angelica I. Tiotiu Silviya Novakova Marina Labor Alexander Emelyanov Stefan Mihaicuta Plamena Novakova Denislava Nedeva Tags: Review Source Type: research

Probiotic treatment for women with gestational diabetes to improve maternal and infant health and well-being.
CONCLUSIONS: Low-certainty evidence means we are not certain if there is any difference between probiotic and placebo groups in maternal hypertensive disorders of pregnancy, caesareans; and large-for-gestational-age babies. There were no adverse events reported by the trials. Due to the variability of probiotics used and small sample sizes of trials, evidence from this review has limited ability to inform practice. Well-designed adequately-powered trials are needed to identify whether probiotics may improve maternal blood glucose levels and/or infant/child/adult outcomes; and whether they can be used to treat GDM. PMI...
Source: Cochrane Database of Systematic Reviews - June 24, 2020 Category: General Medicine Authors: Okesene-Gafa KA, Moore AE, Jordan V, McCowan L, Crowther CA Tags: Cochrane Database Syst Rev Source Type: research

Impact of intramural non-cavity-distorting leiomyoma on placental histopathology and perinatal outcome in singleton live births resulting from in vitro fertilization treatment
ConclusionIntramural non-cavity-distorting myomas have a significant impact on the placental histopathology with a higher incidence of dysfunctional labor. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - June 23, 2020 Category: Reproduction Medicine Source Type: research

Induction of Labor in an Intubated Patient With Coronavirus Disease 2019 (COVID-19).
CONCLUSION: Critically ill patients requiring mechanical ventilation, in this case due to COVID-19, may undergo induction of labor and vaginal delivery when carefully selected. PMID: 32590725 [PubMed - as supplied by publisher] (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - June 23, 2020 Category: OBGYN Authors: Slayton-Milam S, Sheffels S, Chan D, Alkinj B Tags: Obstet Gynecol Source Type: research

Evaluating coagulation status with thromboelastography in a woman with antiphospholipid syndrome and sepsis: a case report
This study presents the case of a pregnant woman with antiphospholipid syndrome (APS) who developed septic shock after labor induction. Prolonged coagulation times suggested a hypocoagulable state and contraindication to anticoagulation. Thromboelastography (TEG) similarly indicated hypocoagulation. To exclude the impact of lupus anticoagulant on the coagulation assays, a mixing test of prolonged activated partial thromboplastin times was conducted. The mixing test confirmed that prolongation of coagulation times in vitro was affected by antiphospholipid antibodies (aPL), such as lupus anticoagulant. The patient was admini...
Source: Journal of Anesthesia - June 21, 2020 Category: Anesthesiology Source Type: research

Management of Gestational Diabetes Mellitus.
Authors: Oskovi-Kaplan ZA, Ozgu-Erdinc AS Abstract Once a woman is diagnosed with gestational diabetes mellitus (GDM), two strategies are considered for management; life-style modifications and pharmacological therapy. The management of GDM aims to maintain a normoglycemic state and to prevent excessive weight gain in order to reduce maternal and fetal complications. Lifestyle modifications include nutritional therapy and exercise. Calorie restriction with a low glycemic index diet is recommended to avoid postprandial hyperglycemia and to reduce insulin resistance. Blood glucose levels, HbA1c levels, and ketonuria ...
Source: Advances in Experimental Medicine and Biology - June 18, 2020 Category: Research Tags: Adv Exp Med Biol Source Type: research

Do fertility treatments affect labor induction success rate? A retrospective cohort study
. (Source: Journal of Maternal-Fetal and Neonatal Medicine)
Source: Journal of Maternal-Fetal and Neonatal Medicine - June 18, 2020 Category: Perinatology & Neonatology Authors: Itai Gat Eran Barzilay Roni Zemet Aya Mohr-Sasson Alon Kedem Raoul Orvieto Jigal Hass Source Type: research

Usefulness of transperineal virtual touch quantification in the cervix for predicting outcome of labor induction
This study aimed to explore the feasibility of transperineal virtual touch tissue quantification (VTQ) for predicting the outcome of labor induction. A total of 80 nulliparous pregnant women were included. Before labor induction, cervical length was measured by B-mode sonography, cervical stiffness was measured by VTQ, and Bishop score was assessed by vaginal examination. Subsequently, labor was induced using standard oxytocin infusion in all patients. Delivery within 24 hours after labor induction was classified as spontaneous delivery; otherwise, cesarean delivery was performed. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - June 18, 2020 Category: Radiology Authors: Xiumei Li, Li Li, Yong Li, Shibao Fang, Cheng Zhao, Yongchun Zhang, Zongli Yang Tags: Original research Source Type: research

A simple, quick, and efficient CRISPR/Cas9 genome editing method for human induced pluripotent stem cells.
Abstract Induced pluripotent stem cells (iPSCs) have become an essential research platform to study different human diseases once being discovered by Dr. Shinya Yamanaka in 2006. Another breakthrough in biomedical research is the application of CRISPR/Cas9 system for genome editing in mammalian cells. Although numerous studies have been done to develop methods for gene editing in iPSCs, the current approaches suffer from several limitations, including time and labor consuming, low editing efficiency, and potential off-target effects. In the current study, we report an electroporation-mediated plasmid CRISPR/Cas9 d...
Source: Acta Pharmacologica Sinica - June 18, 2020 Category: Drugs & Pharmacology Authors: Geng BC, Choi KH, Wang SZ, Chen P, Pan XD, Dong NG, Ko JK, Zhu H Tags: Acta Pharmacol Sin Source Type: research

Preventing COVID-19 Transmission on Labor and Delivery: A Decision Analysis
Conclusion Universal COVID-19 screening is generally the preferred option. However, in locations with high COVID-19 prevalence or where the local societal cost of one HCW being unavailable is the highest such as in rural areas, universal PPE may be cost-effective and preferred. This model may help to provide guidance regarding allocation of resources on L&D during these current and future pandemics. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Am...
Source: American Journal of Perinatology - June 16, 2020 Category: Perinatology & Neonatology Authors: Savitsky, Leah M. Albright, Catherine M. Tags: Original Article Source Type: research

The Role of the IL-1 System in Pregnancy and the Use of IL-1 System Markers to Identify Women at Risk for Pregnancy Complications †.
The Role of the IL-1 System in Pregnancy and the Use of IL-1 System Markers to Identify Women at Risk for Pregnancy Complications†. Biol Reprod. 2020 Jun 16;: Authors: Equils O, Kellogg C, McGregor J, Gravett M, Neal-Perry G, Gabay C Abstract The interleukin (IL)-1 system plays a major role in immune responses and inflammation. The IL-1 system components include IL-1α, IL-1β, IL-1 receptor type 1 and IL-1 receptor type 2 (decoy receptor), IL-1 receptor accessory protein (IL-1RAcP), and IL-1 receptor antagonist (IL-1Ra). These components have been shown to play a role in pregnancy, sp...
Source: Biology of Reproduction - June 16, 2020 Category: Reproduction Medicine Authors: Equils O, Kellogg C, McGregor J, Gravett M, Neal-Perry G, Gabay C Tags: Biol Reprod Source Type: research

Fecal Calprotectin May Predict Adverse Pregnancy-Related Outcomes in Patients with Inflammatory Bowel Disease
ConclusionsFecal calprotectin may be a useful noninvasive marker to predict adverse pregnancy-related outcomes in patients with IBD. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - June 12, 2020 Category: Gastroenterology Source Type: research

Misoprostol Sleepover Camp - A Review of the Vicious Cycle Created by Holding Doses of Prostaglandins During Induction
Induction of labor using prostaglandins is a common and effective strategy for induction of labor. In order to improve safety associated with the administration of prostaglandins, health systems have developed protocols dictating when subsequent doses of prostaglandins must be held. Ideally, these criteria would prevent the administration of prostaglandins when they were likely to cause hyperstimulation. Unfortunately, these protocols are often “triggered” by uterine irritability that is not likely to contribute to hyperstimulation. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - June 12, 2020 Category: OBGYN Authors: Greg J. Marchand Source Type: research

Maternal and Neonatal Hospitalization Costs Associated With Elective Induction of Labor at Term in California, 2007-2011.
Abstract OBJECTIVE: To compare hospitalization costs of pregnancies managed by elective induction of labor to those with spontaneous labor in a large cohort of pregnant women. METHODS: We conducted a retrospective cohort study of women with singleton, nonanomalous births in California from 2007 to 2011. We excluded women with placenta previa, breech presentation, prior cesarean delivery, planned cesarean delivery, medically indicated induction of labor, gestational age less than 37 weeks or at or greater than 41 weeks, and stillbirths. We adjusted hospital charges using a cost-to-charge ratio and costs includ...
Source: Obstetrics and Gynecology - June 11, 2020 Category: OBGYN Authors: Hersh AR, Greiner KS, Garg B, Skeith AE, Caughey AB Tags: Obstet Gynecol Source Type: research

Cost of Elective Labor Induction Compared With Expectant Management in Nulliparous Women.
Abstract OBJECTIVE: To compare the actual health-system cost of elective labor induction at 39 weeks of gestation with expectant management. METHODS: This was an economic analysis of patients enrolled in the five Utah hospitals participating in a multicenter randomized trial of elective labor induction at 39 weeks of gestation compared with expectant management in low-risk nulliparous women. The entire trial enrolled more than 6,000 patients. For this subset, 1,201 had cost data available. The primary outcome was relative direct health care costs of maternal and neonatal care from a health system perspective....
Source: Obstetrics and Gynecology - June 11, 2020 Category: OBGYN Authors: Einerson BD, Nelson RE, Sandoval G, Esplin MS, Branch DW, Metz TD, Silver RM, Grobman WA, Reddy UM, Varner M, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU) Network Tags: Obstet Gynecol Source Type: research

Relations between second-trimester aneuploidy screening results and prediction of labour induction success in term pregnancies.
Authors: Karakoc G, Turgal M, Eroglu H, Cakir C, Yavuz A, Yucel A Abstract We aimed to assess whether the second-trimester maternal serum markers could be used for the prediction of labour induction success. This prospective study enrolled women planned labour induction at term. Women were assigned to one of two groups: vaginal prostaglandin or balloon dilatation. All patients were evaluated for Bishop score, maternal serum oestriol, human chorionic gonadotropin and progesterone at the time of second-aneuploidy screening. The total successful rate for induction of labour was 63.9% in both groups. Maternal serum oes...
Source: Journal of Obstetrics and Gynaecology - June 6, 2020 Category: OBGYN Tags: J Obstet Gynaecol Source Type: research

A comparison of maternal and perinatal outcomes with vaginal delivery: indicated induction versus spontaneous labor
. (Source: Journal of Maternal-Fetal and Neonatal Medicine)
Source: Journal of Maternal-Fetal and Neonatal Medicine - June 4, 2020 Category: Perinatology & Neonatology Authors: Julie R. Whittington Songthip T. Ounpraseuth Everett F. Magann Paul J. Wendel Lisa Newton John C. Morrison Source Type: research

Salivary uric acid as a predictive test of preeclampsia, pregnancy ‐induced hypertension and preterm delivery: A pilot study
This study evaluated the predictive value of longitudinal salivary uric acid measurement.Material and methodsPregnant women (n  = 137) from 20 weeks of gestation were recruited at St Richards Hospital, Chichester, UK, for this prospective cohort study. Weekly samples of salivary uric acid were analyzed until delivery. Information regarding pregnancy and labor were obtained from the patient’s record after delivery. Inde pendentt tests were used to compare mean levels of salivary uric acid in women with hypertensive complications and adverse fetal outcomes with women with normal pregnancies. Main outcome...
Source: Acta Obstetricia et Gynecologica Scandinavica - June 3, 2020 Category: OBGYN Authors: Ida Catharina P üschl, Lisbeth Bonde, Isabel C. Reading, Paddy Maguire, Nicholas S. Macklon, Bas B. Van Rijn Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

The effect of the implementation of institutional checklist on expert opinion of oxytocin use in labor
ConclusionThe implementation of an institutional oxytocin checklist did not affect expert assessment of the use of oxytocin in labor. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - June 2, 2020 Category: OBGYN Source Type: research

miR ‑199a‑3p suppresses cervical epithelial cell inflammation by inhibiting the HMGB1/TLR4/NF‑κB pathway in preterm birth.
miR‑199a‑3p suppresses cervical epithelial cell inflammation by inhibiting the HMGB1/TLR4/NF‑κB pathway in preterm birth. Mol Med Rep. 2020 May 22;: Authors: Peng J, Jiang J, Wang H, Feng X, Dong X Abstract Preterm birth (PTB) is the primary cause of neonatal mortality worldwide. Infection and inflammation are considered to be the primary causes of PTB. Cervical remodeling is an important step in the process of preterm delivery, and the destruction of the cervical epithelial barrier and inflammation are important triggers of cervical remodeling. The aim of the present study was to determine...
Source: Molecular Medicine Reports - May 31, 2020 Category: Molecular Biology Tags: Mol Med Rep Source Type: research

A large subchorionic hematoma in pregnancy: A case report
Conclusion: Though small SCH can be found in quite a few pregnant women and is usually harmless, enormous hematoma can result in adverse pregnancy outcomes. It may be difficult, in some cases, to differentiate it from uterine tumors or placental tumors by means of ultrasonography and magnetic resonance imaging, especially when the mass is hyperechoic under ultrasonography. This case report stresses the importance of regular examinations of pregnant women. (Source: Medicine)
Source: Medicine - May 29, 2020 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Association of Prior Cesarean Delivery With Early Term Delivery and Neonatal Morbidity.
CONCLUSION: Prior cesarean delivery is correlated with earlier delivery and increased neonatal morbidity. Advocating trial of labor after cesarean delivery may provide maternal and neonatal benefit. PMID: 32459429 [PubMed - in process] (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - May 29, 2020 Category: OBGYN Authors: Forde B, DeFranco EA Tags: Obstet Gynecol Source Type: research

Speculum versus digital insertion of Foley catheter for induction of labor in Nulliparas with unripe cervix: a randomized controlled trial
Induction of labor (IoL) is an increasingly common obstetric procedure. Foley catheter IoL is recommended by WHO. It is associated with the lowest rate of uterine hyperstimulation syndrome and similar duration... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - May 29, 2020 Category: OBGYN Authors: Hang Min Chia, Peng Chiong Tan, Sze Ping Tan, Mukhri Hamdan and Siti Zawiah Omar Tags: Research article Source Type: research

39-Week nulliparous inductions are not  elective
In August 2018, Grobman et  al1 published findings from the ARRIVE Trial: A Randomized Trial of Induction vs Expectant Management. More than 6000 women underwent random assignment at 41 academic and community hospitals that were participating in the Maternal-Fetal Medicine Units Network; 3062 women were assigned to labor ind uction, and 3044 women were assigned to expectant treatment. There was no difference in the primary outcome, which was a composite of adverse perinatal outcomes. Women who underwent labor induction were significantly less likely to deliver by cesarean (18.6 % vs 22.2%; relative risk, 0.84; 95% con...
Source: American Journal of Obstetrics and Gynecology - May 28, 2020 Category: OBGYN Authors: Jeny Ghartey, George A. Macones Tags: Editorial Source Type: research

Sonoelastography for the comparative assessment of cervical maturation after different approaches to cervical preparation ahead of labor induction
. (Source: Journal of Maternal-Fetal and Neonatal Medicine)
Source: Journal of Maternal-Fetal and Neonatal Medicine - May 28, 2020 Category: Perinatology & Neonatology Authors: O. G. Pekarev E. S. Brega A. I. Gus S. S. Lunkov G. B. Dikke D. M. Kochev G. T. Sukhikh Source Type: research

Nitrous Oxide Use During Labor: Satisfaction, Adverse Effects, and Predictors of Conversion to Neuraxial Analgesia
DiscussionUnderstanding predictors of conversion from inhaled N2O to neuraxial analgesia may assist perinatal care providers in their discussions with women about analgesia options during labor. N2O is a useful, safe option for labor analgesia in the United States. (Source: Journal of Midwifery and Women's Health)
Source: Journal of Midwifery and Women's Health - May 26, 2020 Category: Midwifery Authors: Priscilla M. Nodine, Michelle R. Collins, Cristina L. Wood, Jessica L. Anderson, Barbara S. Orlando, Bryan K. McNair, David C. Mayer, Deborah J. Stein Tags: Original Research Source Type: research

Induction of labor in continuing pregnancies
Publication date: Available online 12 May 2020Source: Best Practice & Research Clinical Obstetrics & GynaecologyAuthor(s): Lisa D. Levine, Catalina M. Valencia, Jorge E. Tolosa (Source: Best Practice and Research Clinical Obstetrics and Gynaecology)
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - May 25, 2020 Category: OBGYN Source Type: research

Cortisol Regeneration in the Fetal Membranes, A Coincidental or Requisite Event in Human Parturition?
The fetal membranes are equipped with high capacity of cortisol regeneration through the reductase activity of 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1). The expression of 11β-HSD1 in the fetal membranes is under the feedforward induction by cortisol, which is potentiated by proinflammatory cytokines. As a result, the abundance of 11β-HSD1 increases with gestational age and furthermore at parturition with an escalation of cortisol concentration in the fetal membranes. Accumulated cortisol takes parts in a number of crucial events pertinent to the onset of labor in the fetal membranes, including extr...
Source: Frontiers in Physiology - May 25, 2020 Category: Physiology Source Type: research

Comparison of two management options for labor induction following unsuccessful prostaglandin E2 ripening
. (Source: Journal of Maternal-Fetal and Neonatal Medicine)
Source: Journal of Maternal-Fetal and Neonatal Medicine - May 25, 2020 Category: Perinatology & Neonatology Authors: Moti Gulersen Mariella DiSturco David A. Krantz Eran Bornstein Source Type: research

Induction of Labor at Full-term in Pregnant Women With Uncomplicated Singleton Pregnancy: A Systematic Review and Meta-analysis of Randomized Trials
(Acta Obstet Gynecol Scand. 2019;98:958–966) (Source: Obstetric Anesthesia Digest)
Source: Obstetric Anesthesia Digest - May 23, 2020 Category: Anesthesiology Tags: Editorials and Reviews Source Type: research

SMFM Statement on Elective Induction of Labor in Low-Risk Nulliparous Women at Term: The ARRIVE Trial
(Am J Obstet Gynecol. 2019;221:B2–B4) (Source: Obstetric Anesthesia Digest)
Source: Obstetric Anesthesia Digest - May 23, 2020 Category: Anesthesiology Tags: Mother, Fetus, Neonate Source Type: research

Predictors of response after a second attempt of pharmacological labor induction: a retrospective study
AbstractPurposeThe aim of our study was to assess the outcomes of a prolonged induction carried out with a second sequential cycle of pharmacological stimulation after unsatisfactory response to a first attempt, and to highlight variables correlated with higher response rates.MethodsA retrospective study was carried out on 157 women who underwent a two-step labor induction by vaginal prostaglandins followed by a second cycle of prostaglandins or intravenous oxytocin. Outcomes assessed were mode of delivery and maternal and neonatal morbidity. Main variables of pregnancy and delivery were collected to identify factors predi...
Source: Archives of Gynecology and Obstetrics - May 22, 2020 Category: OBGYN Source Type: research

Variations in use of childbirth interventions in 13 high-income countries: A multinational cross-sectional study
by Anna E. Seijmonsbergen-Schermers, Thomas van den Akker, Eva Rydahl, Katrien Beeckman, Annick Bogaerts, Lorena Binfa, Lucy Frith, Mechthild M. Gross, Bj örn Misselwitz, Berglind Hálfdánsdóttir, Deirdre Daly, Paul Corcoran, Jean Calleja-Agius, Neville Calleja, Miriam Gatt, Anne Britt Vika Nilsen, Eugene Declercq, Mika Gissler, Anna Heino, Helena Lindgren, Ank de Jonge BackgroundVariations in intervention rates, without subsequent reductions in adverse outcomes, can indicate overuse. We studied variations in and associations between commonly used childbirth interventions and adverse outcomes, adju...
Source: PLoS Medicine - May 22, 2020 Category: Internal Medicine Authors: Anna E. Seijmonsbergen-Schermers Source Type: research

What women want and why. Women's preferences for induction of labour or expectant management in late-term pregnancy
Both induction of labour at 41 weeks and expectant management until 42 weeks are common management strategies in low-risk pregnancy since there is no consensus on the optimal timing of induction in late-term pregnancy for the prevention of adverse outcomes. Our aim was to explore maternal preference for either strategy and the influence on quality of life and maternal anxiety on this preference. (Source: Women and Birth)
Source: Women and Birth - May 19, 2020 Category: Midwifery Authors: J.K.J. Keulen, P.T. Nieuwkerk, J.C. Kortekaas, J. van Dillen, B.W. Mol, J.A.M. van der Post, E. de Miranda Tags: Original Research Source Type: research

What women want and why. Women's preferences for induction of labour or expectant management in late-term pregnancy.
Abstract BACKGROUND: Both induction of labour at 41 weeks and expectant management until 42 weeks are common management strategies in low-risk pregnancy since there is no consensus on the optimal timing of induction in late-term pregnancy for the prevention of adverse outcomes. Our aim was to explore maternal preference for either strategy and the influence on quality of life and maternal anxiety on this preference. METHODS: Obstetrical low-risk women with an uncomplicated pregnancy were eligible when they reached a gestational age of 41 weeks. They were asked to fill in questionnaires on quality of life (EQ6...
Source: Women Birth - May 19, 2020 Category: Midwifery Authors: Keulen JKJ, Nieuwkerk PT, Kortekaas JC, van Dillen J, Mol BW, van der Post JAM, de Miranda E Tags: Women Birth Source Type: research

Application of psychological suggestion therapy in induced labor of mid-late pregnant women in obstetrics.
Authors: Wang Z, Jia X, An R PMID: 32414229 [PubMed - as supplied by publisher] (Source: Panminerva Medica)
Source: Panminerva Medica - May 17, 2020 Category: General Medicine Tags: Panminerva Med Source Type: research

The Effect of Ultrasound-Measured Preinduction Cervical Length on Delivery Outcome in a Low-Resource Setting.
Conclusion: Transvaginal sonographic measurement of cervical length provides a useful prediction of the likelihood of duration of labour following the induction of labour. It is recommended that IOL should be considered and success anticipated in a parturient with a cervical length less than 3 cm. PMID: 32410909 [PubMed - in process] (Source: The Scientific World Journal)
Source: The Scientific World Journal - May 16, 2020 Category: Science Tags: ScientificWorldJournal Source Type: research

Induction of labor, and physiological and psychological stress responses as expressed by salivary cortisol: a prospective study
ConclusionsInduction does not increase stress during labor. Moreover, it might have a positive effect on reducing cortisol during the latent phase. These findings might reassure women who are concerned about induction of labor. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - May 15, 2020 Category: OBGYN Source Type: research

Rethinking assessment of success of mitigation strategies for elephant-induced crop damage.
We examined the literature on effectiveness of crop-damage-mitigation strategies and identified key gaps in evaluations. We determined there is a need to better understand existing solutions within affected communities and to extend evaluations of effectiveness beyond measurement of efficacy to include rates of and barriers to adoption. We devised a conceptual framework for evaluating effectiveness that incorporates the need for increased emphasis on adoption and can be used to inform the design of future crop-damage mitigation assessments for elephants and conflict species more widely. The ability to prevent crop loss in ...
Source: Conservation Biology - May 14, 2020 Category: Biology Authors: Denninger Snyder K, Rentsch D Tags: Conserv Biol Source Type: research

Decreasing Cesarean Delivery Rates Using a Trial of Labour After Cesarean (TOLAC) Bundle.
CONCLUSIONS: A TOLAC bundle, consisting of provider education, a TOLAC discussion aid, and patient resources, combined with audit and feedback, decreased CD for Robson group 5 patients. PMID: 32389633 [PubMed - as supplied by publisher] (Source: Journal of Obstetrics and Gynaecology Canada : JOGC)
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - May 13, 2020 Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research

Induction of labour in continuing pregnancies
Publication date: Available online 12 May 2020Source: Best Practice & Research Clinical Obstetrics & GynaecologyAuthor(s): Lisa D. Levine, Catalina M. Valencia, Jorge E. Tolosa (Source: Best Practice and Research Clinical Obstetrics and Gynaecology)
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - May 13, 2020 Category: OBGYN Source Type: research

“I guess baby was just too comfy in there…”: A qualitative study of women's experiences of elective late-term induction of labour
The frequency of induction of labour (IOL) in late-term pregnancy has increased significantly, but little is known about how women with uncomplicated pregnancies experience IOL for late-term indication alone. (Source: Women and Birth)
Source: Women and Birth - May 11, 2020 Category: Midwifery Authors: Stina Lou, Kathrine Carstensen, Lone Hvidman, Trine Fritzner Jensen, Lone Neumann, Joke-Gesine Habben, Niels Uldbjerg Tags: < ![CDATA[Original Research]] > Source Type: research

"I guess baby was just too comfy in there …": A qualitative study of women's experiences of elective late-term induction of labour.
CONCLUSIONS: Most women considered the late-term IOL to be a positive experience. Some women requested more information and time to consider alternatives. These women should be provided with supported opportunities to consider the options. PMID: 32404274 [PubMed - as supplied by publisher] (Source: Women Birth)
Source: Women Birth - May 11, 2020 Category: Midwifery Authors: Lou S, Carstensen K, Hvidman L, Jensen TF, Neumann L, Habben JG, Uldbjerg N Tags: Women Birth Source Type: research