Gene expression profiling of vitamin D metabolism enzymes in leukemia and lymphoma patients: molecular aspect interplay of VDR, CYP2R1, and CYP24A1
CONCLUSION: The study revealed a noteworthy difference in VDR protein levels between men and women. The highest mean CYP24A1 protein levels were observed in the age group > 60 years. This study found a significant, moderately positive correlation between VDR protein levels and CYP24A1 protein levels in the male and vitamin D sufficiency groups. In addition, a significant positive correlation was found between VDR mRNA levels and CYP2R1 mRNA levels, VDR mRNA levels and CYP2R1 mRNA levels, and CYP2R1 mRNA levels and CYP24A1 mRNA levels. However, the expression of these genes does not correlate with the protein levels of i...
Source: Molecular Biology Reports - April 17, 2024 Category: Molecular Biology Authors: Anggraini Iriani Andhika Rachman Marsya Kaila Fatina Rizka Kurnia Gemilang Andi Trisnandi Media Fitri Isma Nugraha Source Type: research
Evaluating the Feasibility of a Guided Culturally Adapted Internet-Delivered Mindfulness Intervention for Indonesian University Students Experiencing Psychological Distress
ConclusionsThis study suggested that a counsellor-guided culturally adapted internet-based mindfulness intervention was feasible, acceptable, and associated with improvements in psychological distress, well-being, and mindfulness among university students in Indonesia. A randomized controlled trial with follow-up is needed to evaluate the intervention ’s effectiveness.PreregistrationThis trial was preregistered on the Australian New Zealand Clinical Trial Registry (ACTRN12620000135910). (Source: Mindfulness)
Source: Mindfulness - April 16, 2024 Category: Psychiatry & Psychology Source Type: research
The Role of Vitamin D Binding Protein and Vitamin D Level in Mortality of Sepsis Patients
CONCLUSIONS: Diminished levels of vitamin D binding protein and vitamin D contribute to an increased risk of mortality in septic patients.PMID:38618268 | PMC:PMC11015934 | DOI:10.61186/rbmb.12.3.366 (Source: Mol Biol Cell)
Source: Mol Biol Cell - April 15, 2024 Category: Molecular Biology Authors: Liliriawati Ananta Kahar Yusrawati Yusrawati Jamsari Jamsari Tinni Maskoen Kornelis Aribowo Wiwi Monika Sari Source Type: research
Suicide Behavior Among Indigenous and Non-Indigenous Living with HIV: A Cross-Sectional Study in Indonesia
This study identified the risk of suicidality among PLWHs is high and routine suicide asses sment is prioritized. The findings are also useful for intervention design and the development of clinical practice guidelines to manage the well-being of PLWH such as using digital intervention to cope with hindrances. (Source: Journal of Immigrant and Minority Health)
Source: Journal of Immigrant and Minority Health - April 15, 2024 Category: International Medicine & Public Health Source Type: research
Existential Well-Being in Nature: A Cross-Cultural and Descriptive Phenomenological Approach
AbstractExploring the putative role of nature in human well-being has typically been operationalized and measured within a quantitative paradigm of research. However, such approaches are limited in the extent to which they can capture the full range of how natural experiences support well-being. The aim of the study was to explore personal experiences in nature and consider how they might be important to human health and well-being. Based on a descriptive phenomenological analysis of fifty descriptions of memorable moments in nature from England, Indonesia, and Norway, our findings illustrate a common structure presented u...
Source: Journal of Medical Humanities - April 13, 2024 Category: Medical Ethics Source Type: research
New investigation of encoding secondary metabolites gene by genome mining of a marine bacterium, Pseudoalteromonas viridis BBR56
Pseudoalteromonas viridis strain BBR56 was isolated from seawater at Dutungan Island, South Sulawesi, Indonesia. Bacterial DNA was isolated using Promega Genomic DNA TM050. DNA purity and quantity were assessed u... (Source: BMC Genomics)
Source: BMC Genomics - April 13, 2024 Category: Genetics & Stem Cells Authors: Desy Putri Handayani, Alim Isnansetyo and Indah Istiqomah Tags: Research Source Type: research
Inequalities in women ’s health insurance coverage before and after the implementation of universal health insurance in Indonesia
AbstractIndonesia implemented a National Social Security System (Jaminan Kesehatan Nasional, JKN) in 2014. To examine the changes in the magnitude of socioeconomic inequity in women's health insurance coverage among those of reproductive age, we conducted a repeated cross-sectional study design using data from the Indonesia Demographic and Health Surveys conducted in 2012 and 2017, before and after the implementation of JKN. Results showed that while the JKN program helped to increase health insurance coverage among Indonesian women of childbearing age, low education level and household wealth status were associated with a...
Source: Journal of Public Health Policy - April 12, 2024 Category: Health Management Source Type: research
Essential considerations towards development of effective nasal antibiotic formulation: features, strategies, and future directions
. (Source: Expert Opinion on Drug Delivery)
Source: Expert Opinion on Drug Delivery - April 11, 2024 Category: Drugs & Pharmacology Authors: Sandra Aulia MardikasariG ábor KatonaBence SiposIldikó Csókaa Institute of Pharmaceutical Technology and Regulatory Affairs, Faculty of Pharmacy, University of Szeged, Szeged, Hungaryb Faculty of Pharmacy, Hasanuddin University, Makassar, Indonesia Source Type: research
Effect of a Nutritional Education Program on Children's Undernutrition in Indonesia: A Randomized Controlled Trial
Children's undernutrition is a severe public health issue (Ssentongo et al., 2021). The World Health Organization (WHO, 2021a) defines children's undernutrition as a deficiency or imbalance in the intake of energy and nutrients, and includes wasting (i.e., low weight-for-height), stunting (i.e., low height-for-age), and being underweight (i.e., low weight-for-age). Globally, around 462 million children under 5 years were assessed as being underweight, a million children were stunted, and 45 million exhibited wasting (WHO, 2021b). (Source: Journal of Pediatric Health Care)
Source: Journal of Pediatric Health Care - April 11, 2024 Category: Pediatrics Authors: Raden Ahmad Dedy Mardani, Wan-Ru Wu, Zuhratul Hajri, Zurriyatun Thoyibah, Henny Yolanda, Hui-Chuan Huang Tags: Quantitative Source Type: research
Wolbachia-carrying Aedes mosquitoes for preventing dengue infection
CONCLUSIONS: The included trial demonstrates the potential significant impact of wMel-Wolbachia-carrying Ae aegypti mosquitoes on preventing dengue infection in an endemic setting, and supports evidence reported in non-randomized and uncontrolled studies. Further trials across a greater diversity of settings are required to confirm whether these findings apply to other locations and country settings, and greater reporting of acceptability and cost are important.PMID:38597256 | DOI:10.1002/14651858.CD015636.pub2 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Tilly Fox Yanina Sguassero Marty Chaplin Winsley Rose Dyna Doum Ingrid Arevalo-Rodriguez Gemma Villanueva Source Type: research
Regulatory landscape and public perception for gene-edited bananas in the Southeast Asian region
Transgenic Res. 2024 Apr 10. doi: 10.1007/s11248-024-00379-9. Online ahead of print.ABSTRACTBanana is a premier fruit crop in many parts of the world especially Southeast Asia. The demand for banana has contributed to significant national income to primary banana producers in the SEA region such as the Philippines, Indonesia, Thailand, Vietnam, and Malaysia. However, the widely traded banana industry is plagued by numerous threats including pests and diseases, post-harvest issues and extreme climate vulnerability. To address these challenges, new breeding techniques such as gene editing have been explored for breeding prog...
Source: Transgenic Research - April 10, 2024 Category: Genetics & Stem Cells Authors: Nurzatil Sharleeza Mat Jalaluddin Abdulah Al-Hadi Ahmad Fuaad Rofina Yasmin Othman Source Type: research
Wolbachia-carrying Aedes mosquitoes for preventing dengue infection
CONCLUSIONS: The included trial demonstrates the potential significant impact of wMel-Wolbachia-carrying Ae aegypti mosquitoes on preventing dengue infection in an endemic setting, and supports evidence reported in non-randomized and uncontrolled studies. Further trials across a greater diversity of settings are required to confirm whether these findings apply to other locations and country settings, and greater reporting of acceptability and cost are important.PMID:38597256 | PMC:PMC11005084 | DOI:10.1002/14651858.CD015636.pub2 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Tilly Fox Yanina Sguassero Marty Chaplin Winsley Rose Dyna Doum Ingrid Arevalo-Rodriguez Gemma Villanueva Source Type: research
Regulatory landscape and public perception for gene-edited bananas in the Southeast Asian region
Transgenic Res. 2024 Apr 10. doi: 10.1007/s11248-024-00379-9. Online ahead of print.ABSTRACTBanana is a premier fruit crop in many parts of the world especially Southeast Asia. The demand for banana has contributed to significant national income to primary banana producers in the SEA region such as the Philippines, Indonesia, Thailand, Vietnam, and Malaysia. However, the widely traded banana industry is plagued by numerous threats including pests and diseases, post-harvest issues and extreme climate vulnerability. To address these challenges, new breeding techniques such as gene editing have been explored for breeding prog...
Source: Transgenic Research - April 10, 2024 Category: Genetics & Stem Cells Authors: Nurzatil Sharleeza Mat Jalaluddin Abdulah Al-Hadi Ahmad Fuaad Rofina Yasmin Othman Source Type: research
Wolbachia-carrying Aedes mosquitoes for preventing dengue infection
CONCLUSIONS: The included trial demonstrates the potential significant impact of wMel-Wolbachia-carrying Ae aegypti mosquitoes on preventing dengue infection in an endemic setting, and supports evidence reported in non-randomized and uncontrolled studies. Further trials across a greater diversity of settings are required to confirm whether these findings apply to other locations and country settings, and greater reporting of acceptability and cost are important.PMID:38597256 | PMC:PMC11005084 | DOI:10.1002/14651858.CD015636.pub2 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Tilly Fox Yanina Sguassero Marty Chaplin Winsley Rose Dyna Doum Ingrid Arevalo-Rodriguez Gemma Villanueva Source Type: research
Wolbachia-carrying Aedes mosquitoes for preventing dengue infection
CONCLUSIONS: The included trial demonstrates the potential significant impact of wMel-Wolbachia-carrying Ae aegypti mosquitoes on preventing dengue infection in an endemic setting, and supports evidence reported in non-randomized and uncontrolled studies. Further trials across a greater diversity of settings are required to confirm whether these findings apply to other locations and country settings, and greater reporting of acceptability and cost are important.PMID:38597256 | PMC:PMC11005084 | DOI:10.1002/14651858.CD015636.pub2 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Tilly Fox Yanina Sguassero Marty Chaplin Winsley Rose Dyna Doum Ingrid Arevalo-Rodriguez Gemma Villanueva Source Type: research
