Tetrabenazine for Tardive Tremor in Elderly Adults: A Prospective Follow-up Study

This study aimed to evaluate the efficacy and tolerability of TBZ in elderly patients with TT. Patients (N = 10) received TBZ (25–150 mg/d) for 6 weeks. Five subjects completed the study. Mean TBZ dose at study end was 57.5 ± 37.3 mg/d. Mean Abnormal Involuntary Movement score was 13.3 ± 6.6, mean Tremor Scale score was 2.3 ± 0.9, mean Clinical Global Impression-Change was 3.6 ± 2.2, and mean Geriatric Depression Score was 5.2 ± 4.9; all not significantly changed from baseline. Five patients suffered side effects, including depression (n = 3), parkinsonism (n = 2), akathisia (n = 1), and mild stroke (n = 1). This prospective study does not support TBZ treatment for TT in elderly psychiatric patients.
Source: Clinical Neuropharmacology - Category: Neurology Tags: Original Articles Source Type: research

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Source: The Rest of the Story: Tobacco News Analysis and Commentary - Category: Addiction Source Type: blogs
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Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Bipolar Depression General Medications Self-Help Treatment depression episode Insomnia Mood Disorder National Network of Depression Centers Sleep support Trauma Treatment Resistant Depression Source Type: blogs
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Source: Revista de Psiquiatria Clinica - Category: Psychiatry Source Type: research
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Source: MedPage Today Psychiatry - Category: Psychiatry Source Type: news
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Source: Cerebrovascular Diseases - Category: Neurology Source Type: research
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Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
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Source: Clinical Rehabilitation - Category: Rehabilitation Authors: Tags: Clin Rehabil Source Type: research
Condition:   Post-stroke Depression Interventions:   Device: iPad Application + Usual Rehabilitation;   Behavioral: Usual rehabilitation Sponsor:   Kibi International University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: OnMedica Latest News - Category: UK Health Source Type: news
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