Publication date: Available online 20 May 2019Source: Physics Letters AAuthor(s): Manman Yang, Hongyu Zhu, Wencai Yi, Shangsheng Li, Meihua Hu, Qiang Hu, Baoli Du, Xiaobing Liu, Taichao SuAbstractIn this paper, p-type thermoelectric material Te–Se solid solutions have been successfully prepared by the high-pressure technique. The thermal conductivity of Te was depressed sharply by Se alloying. An extremely low thermal conductivity ∼0.27 W m−1 K−1 was obtained for Te alloyed with 15 mol% Se, which near the theoretical minimum, κmin. The bipolar diffusion effect of Te was suppressed by S...
MMSE Changes During and After ECT in Late-Life Depression: A Prospective Study. Am J Geriatr Psychiatry. 2019 Apr 23;: Authors: Obbels J, Vansteelandt K, Verwijk E, Dols A, Bouckaert F, Oudega ML, Vandenbulcke M, Stek M, Sienaert P Abstract OBJECTIVE: There is ongoing concern about the impact of electroconvulsive therapy (ECT) on cognition in patients with late-life depression (LLD), especially in patients for whom pretreatment Mini-Mental State Exam (MMSE) scores are low. Our aim was to examine the evolution of cognitive effects of ECT, using the MMSE in a large group of patients with LLD. ME...
CONCLUSION: Findings suggest that declining skeletal muscle mitochondrial function in older adults is associated with clinically significant depressive symptoms at follow-up, thereby providing preliminary support for the hypothesis that mitochondrial dysfunction may be a potential key pathophysiological mechanism in adults with LLD. PMID: 31104966 [PubMed - as supplied by publisher]
CONCLUSION: Psilocin and psilocybin showed no antidepressant-like effect in the FSL rats, despite a positive effect in humans. This suggests that other animal models of depression and other behavioural tests may be more appropriate for translational studies in the effects of psilocybin. PMID: 31106729 [PubMed - as supplied by publisher]
CONCLUSIONS: Our results suggest that genetic variation in three genes in the HPA-axis possibly moderate the effects of SLEs in depression. PMID: 31106715 [PubMed - as supplied by publisher]
CONCLUSION: In a context of impairments in mental functioning, sexual enjoyment, symptoms burden, and poor future self-health perspective, breast cancer produced a mean HSU of 0.712. After a period of routine care, there was a small improvement in quality of life, however lower utility estimates were particularly observed in patients with advanced disease and undergoing multiple chemotherapy regimens. PMID: 31106611 [PubMed - as supplied by publisher]
CONCLUSION: The DIL intervention was adapted to the local context for delivery by lay health counselors and was found to be acceptable and feasible among the elderly participants in the study. PMID: 31104614 [PubMed - in process]
Conclusion: It can be said that proposed algorithm efficiently suppresses the influence of noise in the EEG inverse problem using simulated EEG activity and EEG database for depression. Such a system may offer an effective solution for clinicians as a crucial stage of EEG pre-processing in automated depression detection systems and may prevent delay in diagnosis.Eur Neurol 2019;81:63 –75
Authors: Li B, Han L, Cao B, Yang X, Zhu X, Yang B, Zhao H, Qiao W Abstract To improve the liposolubility and blood-brain barrier permeability of magnoflorine, a new formulation of magnoflorine-phospholipid complex was prepared, characterized, and pharmacologically evaluated in the chronic unpredictable mild stress animal model. In this paper, the magnoflorine-phospholipid complex was synthesized and its characterization was determined. The antidepressant-like and antioxidant activity of magnoflorine-phospholipid complex was investigated by behavioral tests and western blotting analysis. As a result, the magnoflori...
Conclusions: NT analysis results showed that HAL and HAR selectively affect AChE in vivo. HAL and HAR may be highly and suitably developed for the treatment of Alzheimer's disease.Graphical abstract