Lipid parameters in a hyperendemic area for malaria

Conclusion: Although other factors might have contributed to lipid profile, the constant exposure to infection by Plasmodium, according to the physiology of the parasite, may have played an important role in defining the lipid parameters observed for this region. Further studies, such as the case--control is needed to confirm this hypothesis.
Source: Lipids in Health and Disease - Category: Lipidology Authors: Source Type: research

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Conclusions: Our findings suggest that some subsets of XPD patients may be at risk of radiosensitivity reactions and treatment with statins and bisphosphonates may be an interesting approach of radioprotection countermeasure. Different mechanistic models were discussed to better understand the potential specificity of the p.[Arg683Trp];[Arg616Pro] XPD mutations . PMID: 31738647 [PubMed - as supplied by publisher]
Source: International Journal of Radiation Biology - Category: Radiology Tags: Int J Radiat Biol Source Type: research
Conclusions Patients are not adequately ready to change their health-related behaviors. Higher cardiovascular risk predicts higher readiness to change health behaviors.
Source: Journal of Nursing Research - Category: Nursing Tags: ORIGINAL ARTICLES Source Type: research
Publication date: Available online 19 November 2019Source: Journal of EthnopharmacologyAuthor(s): Lujie Fan, Ying Peng, Dan Wu, Jianhong Hu, Xin'e Shi, Gongshe Yang, Xiao LiAbstractEthnopharmacological relevanceMulberry leaves are the dry leaves of Morus nigra L. trees, which are widely cultivated in central and southern China. Mulberry has a long history of medicinal use, such as anti-stress, lowering blood glucose and anti-obesity.Aim of the studyExplore the effects of mulberry leaves on fat deposition as well as the underlying mechanisms.Materials and methodsTotal of 48 fattening pigs weighing about 70 kg were randoml...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 19 November 2019Source: Journal of Ayurveda and Integrative MedicineAuthor(s): Rekha Khandia, Chandra Shekhar Pathe, Pratibha Vishwakarma, Kuldeep Dhama, Ashok MunjalAbstractBackgroundInsecticides are widely used in agriculture to curb the loss caused by insects. These insecticides are incorporated into the food chain and accumulate in the human body, as well disturb the various metabolic pathways. Imidacloprid is an insect neurotoxin commonly used in agriculture to control the insect pests. P. niruri is a traditional medicinal shrub widely used as an anti-inflammatory, antipyretic, and a...
Source: Journal of Ayurveda and Integrative Medicine - Category: Complementary Medicine Source Type: research
ConclusionsThe study has provided a way out to combat the toxicity effects associated with bulk statins by synthesis of nanoparticles of statins with more efficacy, more bioavailability, more solubility and more radical scavenging capacity even in lesser dose.Graphical abstract
Source: European Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
Publication date: 19 November 2019Source: Cell Reports, Volume 29, Issue 8Author(s): Ann Ly, Yang Liao, Halina Pietrzak, Lisa J. Ioannidis, Tom Sidwell, Renee Gloury, Marcel Doerflinger, Tony Triglia, Raymond Z. Qin, Joanna R. Groom, Gabrielle T. Belz, Kim L. Good-Jacobson, Wei Shi, Axel Kallies, Diana S. HansenSummaryDespite the key role that antibodies play in protection, the cellular processes mediating the acquisition of humoral immunity against malaria are not fully understood. Using an infection model of severe malaria, we find that germinal center (GC) B cells upregulate the transcription factor T-bet during infecti...
Source: Cell Reports - Category: Cytology Source Type: research
Publication date: 19 November 2019Source: Cell Reports, Volume 29, Issue 8Author(s): Wiebke Hartmann, Marie-Luise Brunn, Nadine Stetter, Nicola Gagliani, Franziska Muscate, Stephanie Stanelle-Bertram, Gülsah Gabriel, Minka BreloerSummaryHelminth parasites infect more than a quarter of the human population and inflict significant changes to the immunological status of their hosts. Here, we analyze the impact of helminth infections on the efficacy of vaccinations using Litomosoides sigmodontis-infected mice. Concurrent helminth infection reduces the quantity and quality of antibody responses to vaccination against seaso...
Source: Cell Reports - Category: Cytology Source Type: research
Molecular and Histopathological Data on Levisunguis subaequalis Curran, Overstreet, Collins &Benz, 2014 (Pentastomida: Eupentastomida: Porocephalida: Porocephaloidea: Sebekidae: Sebekinae) from Gambusia affinis in Alabama, USA. J Parasitol. 2019 Dec;105(6):827-839 Authors: Woodyard ET, Stilwell JM, Camus AC, Rosser TG Abstract Levisunguis subaequalis Curran, Overstreet, Collins &Benz, 2014 , was recently described from the lungs of the definitive hosts, softshell turtles, Apalone ferox (Schneider, 1783), and Apalone spinifera aspera (Agassiz, 1857) as well as the viscera of an intermediate hos...
Source: The Journal of Parasitology - Category: Parasitology Authors: Tags: J Parasitol Source Type: research
This study highlights the remarkable genetic diversity in Blastocystis sp. isolates from zoo animals and provides the first molecular evidence from spotted deer, gayal and grey langur. Due to circulation of large percentage of potentially zoonotic subtypes in the wild animals, there is a higher risk of zoonotic transmission of Blastocystis sp. in the zoo keepers and visitors.Graphical abstract
Source: International Journal for Parasitology: Parasites and Wildlife - Category: Parasitology Source Type: research
Authors: El Menshawe SF, Nafady MM, Aboud HM, Kharshoum RM, Elkelawy AMMH, Hamad DS Abstract The current study aimed to encapsulate fluvastatin sodium (FVS), a member of the statins family possessing pleiotropic effects in rheumatoid arthritis (RA), into spanlastic nanovesicles (SNVs) for transdermal delivery. This novel delivery could surmount FVS associated oral encumbrances such as apparent first-pass effect, poor bioavailability and short elimination half-life, hence, accomplishing platform for management of RA. To consummate this objective, FVS-loaded SNVs were elaborated by thin film hydration method, utilizi...
Source: Drug Delivery - Category: Drugs & Pharmacology Tags: Drug Deliv Source Type: research
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