Effects of Sodium Bisulfite With or Without Procaine Derivatives on Axons of Cultured Mouse Dorsal Root Ganglion Neurons

Conclusions: NaHSO3 resulted in a dose-dependent damage to the cell membrane and axonal transport, especially when used in combination with procaine or chloroprocaine.
Source: Regional Anesthesia and Pain Medicine - Category: Anesthesiology Tags: Original Articles Source Type: research

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In this study, a total of 90 patients with primary liver cancer who received hepatectomy in our hospital from July 2020 to July 2021 were included as the research subject. The changes in hemorheology, stress-related indexes, cognitive function, postoperative pain, and gastrointestinal function were compared between the two groups The results showed that SGB combined with general anesthesia can effectively reduce hemodynamic fluctuations in elderly partial hepatectomy patients, alleviate surgical stress, promote postoperative recovery of cognitive function and gastrointestinal function with high safety, and is worthy of cli...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Authors: Source Type: research
Although a stellate ganglion block (SGB) increases tissue blood flow in the mandibular region, the change in tissue oxygenation after SGB and therapeutic effect of SGB for postoperative mandibular nerve hypoesthesia remain to be established. The study aim was to measure the change in tissue oxygenation in the mandibular region after SGB.
Source: Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Tags: Anesthesia/TMJ Dysfunction/Facial Pain Source Type: research
CONCLUSIONS: Chronic neuropathic pain is a common condition and carries significant morbidity and impact on the quality of life. Recent evidence supports the use of DRG neuromodulation as an effective technique to control chronic pain. Though studies are still emerging, the evidence appears to support this technique. Further studies, including large randomized trials evaluating DRG modulation versus other interventional and non-interventional techniques, are needed to further elucidate the efficacy of this method. These studies are also likely to inform the patient selection and the course of treatment.PMID:34336621 | PMC:...
Source: Pain Physician - Category: Anesthesiology Authors: Source Type: research
CONCLUSIONS: SPGB should be considered as a first treatment modality for PDPH. Moreover, the results indicate that TCD is a successful objective tool in assessing a transnasal sphenopalatine ganglion block.PMID:34323454
Source: Pain Physician - Category: Anesthesiology Authors: Source Type: research
Eur J Pharmacol. 2021 Jul 10;908:174322. doi: 10.1016/j.ejphar.2021.174322. Online ahead of print.ABSTRACTNeuropathic pain is a common chronic pain condition with major impact on quality of life. However, its physiopathologic mechanism remains unknown and pain management is still a challenge. Accumulating evidence indicated that C-X-C chemokine receptor type 4 (CXCR4) played a critical role in the process of pain. Thus, the present study aimed to investigate whether intervertebral foramen injection of CXCR4 antagonist, plerixafor, was able to relieve neuropathic pain and explore the possible underlying mechanism. Chronic c...
Source: European Journal of Pharmacology - Category: Drugs & Pharmacology Authors: Source Type: research
Pain Physician. 2021 Jul;24(4):E443-E451.ABSTRACTBACKGROUND: Despite being invasive, with serious complications, epidural blood patch (EBP) is still considered the gold standard therapy for Post Dural Puncture Headache (PDPH). The use of Peripheral nerve blocks for PDPH are studied here.OBJECTIVES: To investigate the efficacy of sphenopalatine ganglion block (SPGB) and greater occipital nerve block (GONB) to relieve PDPH and its associated symptoms.STUDY DESIGN: Randomized comparative single-blind trial.SETTING: A University hospital.METHODS: Patients who received spinal anesthesia for elective cesarean section, and then d...
Source: Pain Physician - Category: Anesthesiology Authors: Source Type: research
CONCLUSION: Extracranial non-Gasserian-ganglion RF can achieve satisfactory results and improve the safety of radiofrequency treatment for trigeminal neuralgia.PMID:34213867
Source: Pain Physician - Category: Anesthesiology Authors: Source Type: research
Korean J Pain. 2021 Jul 1;34(3):304-314. doi: 10.3344/kjp.2021.34.3.304.ABSTRACTBACKGROUND: The study investigated virtual reality (VR) immersion in alleviating procedure-related pain in patients with chronic pain undergoing fluoroscopy-guided minimally-invasive intervention in a prone position at an outpatient clinic.METHODS: In this prospective randomized controlled study, 38 patients undergoing lumbar sympathetic ganglion block were randomized into either the VR or the control group. In the VR group, procedure-related pain was controlled via infiltration of local anesthetics while watching a 30-minute VR hypnotic progra...
Source: Korean Journal of Pain - Category: Anesthesiology Authors: Source Type: research
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