What is a Carcinoembryonic Antigen (CEA) Tumor...

A carcinoembryonic antigen (CEA) tumor marker test is a blood test that might be ordered prior to and during breast cancer treatment to monitor your progress. The results of this test may show whether your treatment is effective for your cancer. Learn more about blood testing and the CEA blood test.
Source: About.com Breast Cancer - Category: Cancer & Oncology Authors: Tags: health Source Type: news

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Source: Neuro-Ophthalmology - Category: Opthalmology Authors: Source Type: research
Publication date: Available online 25 January 2020Source: Journal of Pharmaceutical and Biomedical AnalysisAuthor(s): Mirza Muhammad Faran Ashraf Baig, Wing-Fu Lai, Reyaj Mikrani, Mehreen Jabeen, Muhammad Naveed, Muhammad Abbas, Muhammad Asim Farooq, Anam Ahsan, Said Abasse Kassim, Ghulam Jilany Khan, Muhammad Tayyab AnsariAbstractDNA based nano-carriers synthesized from short circular scaffolds (circular DNA nanotechnology) attains stiffer topology for ligand functionalization (neuregulin-1/NRG-1 ligand) and biological applications (targeted drug delivery). Daunorubicin (DR) is a hydrophobic chemical that requires robust ...
Source: Journal of Pharmaceutical and Biomedical Analysis - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 25 January 2020Source: International Journal of PharmaceuticsAuthor(s): Joan Puig-Rigall, Celia Fernandez-Rubio, Javier González-Benito, Judith E. Houston, Aurel Radulescu, Paul Nguewa, Gustavo González-GaitanoAbstractMiltefosine (MF), an alkylphospholipid originally developed for breast cancer treatment, is a highly active drug for the treatment against leishmaniasis, a neglected tropical disease considered the world’s second leading cause of death by a parasitic agent after malaria. MF exhibits dose-limiting gastrointestinal side effects in patients and its penetrati...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
Publication date: April 2020Source: Biomedicine &Pharmacotherapy, Volume 124Author(s): Huan Gao, Di Liang, Chenchen Li, Guoxing Xu, Mengnan Jiang, Heng Li, Jianyuan Yin, Yanqing SongAbstract20(S)-Rh2 is a ginsenoside isolated from Panax ginseng, which exhibits anti-cancer activities on various human cancer cells. A novel 20(S)-Rh2 derivative, 2-Deoxy-Rh2 was synthesized and hybridized with protopanaxadiol and 2-deoxy-glucose in an attempt to enhance the anticancer activity. Through screening the antitumor effect against various cell lines by MTT assay, 2-Deoxy-Rh2 especially resulted in a concentration-dependent and ti...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Authors: Kang YJ, Lee HB, Kim YG, Han J, Kim Y, Yoo TK, Lee ES, Moon HG, Noh DY, Han W Abstract Objective: While the value of Ki-67 has been recognized in breast cancer, controversy also exists. The goal of this study is to show the prognostic value of Ki-67 according to progesterone receptor (PgR) expression in patients who have estrogen receptor- (ER-) positive, human epidermal growth factor receptor 2- (HER2-) negative early breast cancer. Methods: The records of nonmetastatic invasive breast cancer patients who underwent surgery at a single institution between 2009 and 2012 were reviewed. Primary end point ...
Source: Journal of Oncology - Category: Cancer & Oncology Tags: J Oncol Source Type: research
Authors: Geng W, Dong K, Pu Q, Lv Y, Gao H Abstract SHOC2 leucine rich repeat scaffold protein (SHOC2) has been identified as a positive regulator of the Ras pathway; however, the function of SHOC2 in breast cancer has rarely been explored. The current study investigated the effects of SHOC2 on breast cancer cell growth and evaluated its prognostic value in patients with breast cancer. The effects of SHOC2 on MCF‑7 and MDA‑MB‑231 breast cancer cells were studied using short hairpin RNA. In total, 120 pairs of formalin‑fixed, paraffin‑embedded breast cancer tissue specimens were compared to normal tis...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Identification of key genes as potential biomarkers for triple‑negative breast cancer using integrating genomics analysis. Mol Med Rep. 2020 Feb;21(2):557-566 Authors: Zhong G, Lou W, Shen Q, Yu K, Zheng Y Abstract Triple‑negative breast cancer (TNBC) accounts for the worst prognosis of all types of breast cancers due to a high risk of recurrence and a lack of targeted therapeutic options. Extensive effort is required to identify novel targets for TNBC. In the present study, a robust rank aggregation (RRA) analysis based on genome‑wide gene expression datasets involving TNBC patients from the Gen...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Publication date: Available online 25 January 2020Source: Meta GeneAuthor(s): Sai Gayathri Hari, Sandhya Annamaneni, Santhoshi Rani Nanchari, Phannibhushann Meka, Vishnupriya Satti
Source: Meta Gene - Category: Genetics & Stem Cells Source Type: research
CONCLUSION: Mammography was more accurate than ultrasonography in measuring the largest cancer diameter in DCIS of breast cancer. The correlation coefficient improved in the group of almost entirely fatty/ scattered areas of fibroglandular dense breast or in microcalcification negative group. PMID: 31975667 [PubMed - in process]
Source: Current Medical Imaging Reviews - Category: Radiology Tags: Curr Med Imaging Rev Source Type: research
CONCLUSION: Results show that the proposed system for entirely fat, scattered fibroglandular densities, heterogeneously dense, and extremely dense breast achieved 100, 99, 99 and 98% true malignant rate, respectively with cross-validation procedure. PMID: 31975666 [PubMed - in process]
Source: Current Medical Imaging Reviews - Category: Radiology Tags: Curr Med Imaging Rev Source Type: research
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