Gellar: Let's protect our babies
In babies, pertussis -- also known as whooping cough -- can be fatal. In a majority of infant cases, researchers found family members were responsible.
This study explored how health is associated with legislative activity by examining whether outbreaks of vaccine-preventable diseases, such as measles, mumps, whooping cough and chickenpox, were associated with the introduction of legislation in states to change vaccine exemption laws.
LAKEVILLE (CBS) — Two students have come down with whooping cough at the Freetown-Lakeville Middle School and there’s concern there may be more. “We have several suspect cases and two students with cultures pending,” Lakeville Public Health Nurse Lori Desmarais said in a letter to the school principal Wednesday. Desmarais said they’re trying to reach all students that may have been exposed. She’s also notified the Massachusetts Department of Public Health. Read: Whooping Cough Fact Sheet Whooping cough, which is also known as pertussis, is a highly contagious bacterial infection that dev...
WHOOPING cough bacteria can “lurk silently” in the noses and throats of healthy people, researchers in the UK have discovered. So how can you prevent the illness, what symptoms should you look out for, and how can you treat it?
In this study, we used gel-free nanoLC-MS/MS-based proteomics to investigate whether Hfq, a highly conserved post-transcriptional regulatory protein, is involved in B. pertussis adaptation to low iron environment. To this end, we compared the protein profiles of wild type B. pertussis and its isogenic hfq deletion mutant strain under iron-replete and iron-depleted conditions. Almost of 33% of the proteins identified under iron starvation was found to be Hfq-dependent. Among them, proteins involved in oxidative stress tolerance and virulence factors that play a key role in the early steps of host colonization and bacterial ...
The Aryl Hydrocarbon Receptor (AhR) is a transcription factor that, when activated by ligand-binding, has been shown to regulate the immune response. Pertussis Toxin (PTX) is a virulence factor found in Bordetella pertussis, a human respiratory pathogen that causes whooping cough. PTX promotes colonization and disease promotion by triggering a heightened inflammatory response. The role of AhR in the regulation of PTX-mediated inflammation has not previously been studied. In the current study, we investigate if AhR activation by 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a well characterized ligand, can attenuate PTX-media...
Alberta Health Services has declared a whooping cough outbreak in part of southern Alberta.
Conclusion. Our novel MLVA method has high discriminatory power for genotyping human B. parapertussis. Regarding this organism, this genotyping system is a promising tool for epidemiological surveillance and investigating outbreaks. PMID: 31613204 [PubMed - as supplied by publisher]
Influenza and pertussis cause substantial disease burden among pregnant women and infants too young to be vaccinated.
Only one-third of pregnant women get flu and Tdap shots, despite the fact they vaccines lower the risks that they and their babies will be hospitalized for the infections, worrying CDC data revel.
About two-thirds of pregnant women in the United States don't get vaccinated against both flu and whooping cough, putting them and their newborns at risk, a new report from the CDC says.