Perspective on a Risk Score for Cardiac Transplantation Editorials

Source: Circulation: Heart Failure - Category: Cardiology Authors: Tags: CV surgery: transplantation, ventricular assistance, cardiomyopathy Editorials Source Type: research

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This study aimed to develop and validate a competing risk nomogram for predicting all-cause mortality and heart transplantation (HT) before first appropriate shock in non-ischaemic dilated cardiomyopathy (DCM) patients receiving implantable cardioverter-defibrillators (ICD).Methods and resultsA total of 218 consecutive DCM patients implanted with ICD between 2010 and 2019 at our institution were retrospectively enrolled. Cox proportional hazards model was primarily built to identify variables associated with death and HT. Then, a Fine –Gray model, accounting for the appropriate shock as a competing risk, was construc...
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Original Article Source Type: research
Cardiovascular diseases are among the most prevalent causes of morbidity and mortality in patients with Systemic Lupus Erythematosus (SLE). Pericarditis is the most common cardiac manifestation of SLE, although myocarditis, cardiomyopathy, cardiogenic shock, and end stage systolic heart failure (HF) have been reported with limited therapeutic options. Conventional wisdom regards SLE as a relative contraindication for heart transplantation due to risk of disease recurrence in the transplanted organ.
Source: Heart and Lung - Category: Intensive Care Authors: Tags: Case Report Source Type: research
We report a family with heterozygous deletion of exons 3–6 of the LMNA gene. The main presentation of affected family members was characterized by ventricular and supraventricular arrhythmias, atrioventricular (AV) block and sudden cardiac death (SCD) but also by severe dilative cardiomyopathy (DCM). We report on two siblings, a 36-year-old female and her 40-year-old brother, who suffer from heart failure with mildly reduced ejection fraction, AV conduction delays and premature ventricular complexes. Their 65-year-old mother underwent heart transplantation at the age of 55 due to advanced heart failure. Originall...
Source: Genes - Category: Genetics & Stem Cells Authors: Tags: Case Report Source Type: research
ConclusionsShort-term and long-term post HT outcomes among patients with sarcoid cardiomyopathy are similar to those with common types of non-ischaemic cardiomyopathy.
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Original Article Source Type: research
AbstractCardiac disease has emerged as a leading cause of mortality in Duchenne muscular dystrophy in the current era. This survey sought to identify the diagnostic and therapeutic approach to DMD among pediatric cardiologists in Advanced Cardiac Therapies Improving Outcomes Network. Pediatric cardiology providers within ACTION (a multi-center pediatric heart failure learning network) were surveyed regarding their approaches to cardiac care in DMD. Thirty-one providers from 23 centers responded. Cardiac MRI and Holter monitoring are routinely obtained, but the frequency of use and indications for ordering these tests varie...
Source: Mammalian Genome - Category: Genetics & Stem Cells Source Type: research
Rev Cardiovasc Med. 2021 Dec 22;22(4):1341-1355. doi: 10.31083/j.rcm2204140.ABSTRACTOn an annual basis, heart failure affects millions of people globally. Despite improvements in medications and percutaneous interventions, heart failure secondary to ischemic cardiomyopathy remains an important health issue. A large proportion of healthcare budgets are also dedicated to complications related to ischemic cardiomyopathy and heart failure. Drugs and mechanical devices have an ever-expanding role in our management of this growing patient population. However, cardiac transplantation continues to be the gold standard for treating...
Source: Reviews in Cardiovascular Medicine - Category: Cardiology Authors: Source Type: research
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