Uganda: Govt Can Now Test for Ebola, Marburg

[New Vision]The Ministry of Health can now test for Ebola, Marburg and yellow fever and there is no longer need to fly out specimens abroad for testing, a parliament committee has heard.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news

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A woman and her child were confirmed to be the first two Ebola cases in Congo's South Kivu province, health ministry says.
Source: CBC | Health - Category: Consumer Health News Tags: News/Health Source Type: news
Reports that Ebola has been "cured" are greatly exaggerated. Here's what new drugs can do for those sickened in the latest outbreak -- and what they can't.
Source: Los Angeles Times - Science - Category: Science Authors: Source Type: news
Condition:   Yellow Fever Intervention:   Biological: Yellow fever vaccine, Institut Pasteur Sponsors:   University of Oxford;   KEMRI-Wellcome Trust Collaborative Research Program;   Institut Pasteur;   MRC/UVRI Uganda Research Unit on Aids;   Epicentre, Paris, France. Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Congo's year-long Ebola outbreak has spread to a new province, with two cases, including one death, confirmed in South Kivu, according to the government health ministry
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
A woman and her child were the first two cases confirmed with Ebola in Congo's South Kivu region this week, opening a new front in the fight against the outbreak.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Publication date: Available online 15 December 2017 Source:Antiviral Research Author(s): Julia Ma, Xuexiang Zhang, Veronica Soloveva, Travis Warren, Fang Guo, Shuo Wu, Huagang Lu, Jia Guo, Qing Su, Helen Shen, Eric Solon, Mary Ann Comunale, Anand Mehta, Ju-Tao Guo, Sina Bavari, Yanming Du, Timothy M. Block, Jinhong Chang Targeting host functions essential for viral replication has been considered as a broad spectrum and resistance-refractory antiviral approach. However, only a few host functions have, thus far, been validated as broad-spectrum antiviral targets in vivo. ER α-glucosidases I and II have been demonstra...
Source: Antiviral Therapy - Category: Virology Source Type: research
Enhancing the antiviral potency of ER α-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo. Antiviral Res. 2017 Dec 15;: Authors: Ma J, Zhang X, Soloveva V, Warren T, Guo F, Wu S, Lu H, Guo J, Su Q, Shen H, Solon E, Comunale MA, Mehta A, Guo JT, Bavari S, Du Y, Block TM, Chang J Abstract Targeting host functions essential for viral replication has been considered as a broad spectrum and resistance-refractory antiviral approach. However, only a few host functions have, thus far, been validated as broad-spectrum antiviral targets in vivo. ER α-glucosidase...
Source: Antiviral Research - Category: Virology Authors: Tags: Antiviral Res Source Type: research
Publication date: Available online 10 November 2016 Source:Antiviral Research Author(s): Justin G. Julander, Venkatraman Siddharthan, Joe Evans, Ray Taylor, Kelsey Tolbert, Chad Apuli, Jason Stewart, Preston Collins, Makda Gebre, Skot Neilson, Arnaud Van Wettere, Young-Min Lee, William P. Sheridan, John D. Morrey, Y.S. Babu Zika virus (ZIKV) is currently undergoing pandemic emergence. While disease is typically subclinical, severe neurologic manifestations in fetuses and newborns after congenital infection underscore an urgent need for antiviral interventions. The adenosine analog BCX4430 has broad-spectrum activity again...
Source: Antiviral Therapy - Category: Virology Source Type: research
Abstract Zika virus (ZIKV) is currently undergoing pandemic emergence. While disease is typically subclinical, severe neurologic manifestations in fetuses and newborns after congenital infection underscore an urgent need for antiviral interventions. The adenosine analog BCX4430 has broad-spectrum activity against a wide range of RNA viruses, including potent in vivo activity against yellow fever, Marburg and Ebola viruses. We tested this compound against African and Asian lineage ZIKV in cytopathic effect inhibition and virus yield reduction assays in various cell lines. To further evaluate the efficacy in a relev...
Source: Antiviral Research - Category: Virology Authors: Tags: Antiviral Res Source Type: research
Between 15 and 18 March 2016, the National IHR Focal Point of Kenya notified WHO of 2 imported cases of yellow fever (YF).
Source: WHO Disease Outbreaks - Category: Infectious Diseases Tags: risk assessment [subject], viral haemorrhagic fever [subject], haemorrhagic, crimean-congo haemorrhagic fever, ebola haemorrhagic fever, marburg haemorrhagic fever, yellow fever [subject], yellow fever [subject], African Region [region], Disease outbreak Source Type: news
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