Integrated psychological therapy: effectiveness in schizophrenia inpatient settings related to patients' age.

Integrated psychological therapy: effectiveness in schizophrenia inpatient settings related to patients' age. Am J Geriatr Psychiatry. 2013 Mar;21(3):231-41 Authors: Mueller DR, Schmidt SJ, Roder V Abstract OBJECTIVE: Elderly people with schizophrenia often suffer from cognitive impairments, which affect their social functioning. Today, only a few therapy approaches for middle-aged and older patients are available. The Integrated Psychological Therapy (IPT) combines neurocognitive and social cognitive interventions with social skills approaches. The aim of this study was to evaluate (1) whether IPT is effective in younger patients (age 
Source: Am J Geriatr Psychia... - Category: Geriatrics Authors: Tags: Am J Geriatr Psychiatry Source Type: research

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Brexpiprazole is a new atypical antipsychotic for schizophrenia management and as adjunct in major depressive disorder (MDD). We searched randomized controlled trials (RCT) to review brexpiprazole efficacy and tolerability in acute management of schizophrenia and MDD using PubMed, EUDRACT, ClinicalTrials.gov and Cochrane Central Register of Controlled Trials. A meta-analysis was conducted using the identified 14 RCT to assess its efficacy using positive and negative syndrome scale (PANSS), clinical global impressions – severity of illness (CGI-S), personal and social performance scale (PSP), Montgomery–Ås...
Source: International Clinical Psychopharmacology - Category: Psychiatry Tags: Review Articles Source Type: research
Clozapine, an antipsychotic developed in 1958, is considered the gold standard and the treatment of choice in treatment-resistant schizophrenia despite its side effects and despite 40–70% of these patients not responding to clozapine. In the last decade, new antipsychotics, such as paliperidone palmitate (PP), have emerged as well as its long acting-injectable (LAI) formulations, available as PP-1-monthly (PP1M) and the newest PP-3-montlhy (PP3M). Despite paliperidone having shown a similar efficacy as others antipsychotics for the treatment of schizophrenia, and that PP3M has been shown to reduce relapses compared t...
Source: International Clinical Psychopharmacology - Category: Psychiatry Tags: Original Articles Source Type: research
Conditions:   Schizophrenia;   Schizo Affective Disorder;   Bipolar Disorder;   Major Depressive Disorder Interventions:   Behavioral: Switch - Individual sessions;   Behavioral: Switch - Group programme Sponsors:   University of Liege;   FNRS Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Schizophrenia;   Schizoaffective Disorder;   Delusional Disorder;   Major Depressive Disorder With Psychotic Features Interventions:   Behavioral: Collaborative Decision Skills Training;   Behavioral: Money Management Sponsor:   VA Office of Research and Development Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Schizophrenia;   Schizo Affective Disorder;   Bipolar Disorder;   Major Depressive Disorder Interventions:   Behavioral: Switch - Individual sessions;   Behavioral: Switch - Group programme Sponsors:   University of Liege;   FNRS Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Schizophrenia;   Schizoaffective Disorder;   Delusional Disorder;   Major Depressive Disorder With Psychotic Features Interventions:   Behavioral: Collaborative Decision Skills Training;   Behavioral: Money Management Sponsor:   VA Office of Research and Development Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 26 March 2020Source: Brain, Behavior, and ImmunityAuthor(s): Alexander Kalinkovich, Michael Pouyrovsky, Regina Nasyrova, Gregory Livshits
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
AbstractAimTo investigate whether circulating T cells including regulatory T cells (Treg) and derived cytokines contribute to the immune imbalance observed in schizophrenia.MethodsForty patients with schizophrenia and 40 age, sex, body mass index, education, and smoking status –matched healthy controls (HC) are included in the study. We stained cells with anti-CD14, anti-CD3, anti-CD4, anti-CD8, anti-CD19, anti-CD20, and anti-CD16/56. Peripheral blood mononuclear cells (PBMCs) were isolated and stained with the human FoxP3 kit containing anti-CD4/anti-CD25 and intracell ular anti-Foxp3. PBMCs were cultured for 72&nbs...
Source: Psychopharmacology - Category: Psychiatry Source Type: research
ConclusionThis study provides evidence that metacognitive training is related to the modulation of DMN homogeneity in schizophrenia.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conditions:   Obsessive-Compulsive Disorder;   Obsessive-Compulsive Behavior;   Schizophrenia;   Delusional Disorder;   Brief Psychotic Disorder;   Schizo Affective Disorder;   Other Psychoses;   Unspecified Psychosis Intervention:   Drug: Rituximab Sponsors:   Uppsala University Hospital;   Uppsala University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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