Sudan: Malaria Patients Die After Using Expired Medicine

[Radio Dabanga]Sirba Locality -Residents of Sirba locality in West Darfur complain about expired anti-malarial medicines being sold on the market.
Source: AllAfrica News: Malaria - Category: Infectious Diseases Source Type: news

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Publication date: 19 November 2019Source: Cell Reports, Volume 29, Issue 8Author(s): Ann Ly, Yang Liao, Halina Pietrzak, Lisa J. Ioannidis, Tom Sidwell, Renee Gloury, Marcel Doerflinger, Tony Triglia, Raymond Z. Qin, Joanna R. Groom, Gabrielle T. Belz, Kim L. Good-Jacobson, Wei Shi, Axel Kallies, Diana S. HansenSummaryDespite the key role that antibodies play in protection, the cellular processes mediating the acquisition of humoral immunity against malaria are not fully understood. Using an infection model of severe malaria, we find that germinal center (GC) B cells upregulate the transcription factor T-bet during infecti...
Source: Cell Reports - Category: Cytology Source Type: research
(Duke University) Engineers at Duke University have developed a microscope that adapts its lighting angles, colors and patterns while teaching itself the optimal settings needed to complete a given diagnostic task. In the initial proof-of-concept study, the microscope simultaneously developed a lighting pattern and classification system that allowed it to quickly identify red blood cells infected by the malaria parasite more accurately than trained physicians and other machine learning approaches.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Clinical manifestation of malaria is mainly due to intra-erythrocytic development of Plasmodium parasites. Plasmodium falciparum merozoites, the invasive form of the blood-stage parasite, invade human erythrocytes in a complex but rapid process. This multi-step progression involves interactions between parasite and human host proteins. Here we show that antibodies against a vaccine antigen, PfGAMA, co-immunoprecipitate with PfMSP10. This interaction was validated as direct by surface plasmon resonance analysis. We then demonstrate that antibodies against PfMSP10 have growth inhibitory activity against cultured parasites, w...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Conditions:   Malaria;   Malaria, Asymptomatic Parasitaemia Intervention:   Combination Product: Artemisinin Combination Therapy ACTs Sponsors:   Noguchi Memorial Institute for Medical Research;   World Health Organization Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
An experimental study tests 56 traditional soup broths and finds that some of them contain ingredients that have antimalarial properties.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news
Conditions:   Malaria;   Malaria, Asymptomatic Parasitaemia Intervention:   Combination Product: Artemisinin Combination Therapy ACTs Sponsors:   Noguchi Memorial Institute for Medical Research;   World Health Organization Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
A school project on traditional soups illustrates the mysterious world of science and how solutions might be found in ancient ways.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
(Walter and Eliza Hall Institute) A discovery about how the immune system responds to malaria infection could lead to better treatments for hepatitis C, HIV and lupus, say Melbourne researchers. The research team showed, in laboratory models, that strong inflammatory signals caused by malaria infection activate molecules that trigger the production of highly potent antibodies to fight the disease.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
[The Conversation Africa] More than 200 million people around the world suffered from malaria in 2017. Over 400,000 died. The vast majority - around 90% - were in Africa, where many are all too familiar with the devastating impact of the disease. Young children and pregnant women are the most vulnerable.
Source: AllAfrica News: Malaria - Category: Infectious Diseases Source Type: news
Malaria is a major public health problem in the China –Myanmar border region. The genetic structure of malaria parasite may affect its transmission model and control strategies. The present study was to analyse...
Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Research Source Type: research
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