The efficacy in melasma treatment using a 1410 nm fractional photothermolysis laser

Conclusions1410 nm fractional photothermolysis laser treatment is a safe and temporary effective procedure for melasma; however, long‐term follow‐up is still needed. Only 5% coverage should be used to minimize risks of adverse effects.
Source: Journal of the European Academy of Dermatology and Venereology - Category: Dermatology Authors: Tags: Original Article Source Type: research

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Australas J Dermatol. 2021 Oct 10. doi: 10.1111/ajd.13730. Online ahead of print.ABSTRACTHypertrophic scars present collagen deposition and an abnormal extracellular matrix that cause abnormal shape changes and limit normal movement. Although fractional carbon dioxide (CO2 ) laser therapy has provided promising evidence, the improvement of scarring has not been thoroughly reviewed. A systematic review of prospective randomised trial articles collected from PubMed, MEDLINE, EMBASE, Cochrane and Scopus databases was conducted on 15 March 2020 in accordance with the PRISMA-P statement. Types and duration of fractional carbon ...
Source: The Australasian Journal of Dermatology - Category: Dermatology Authors: Source Type: research
AbstractThe purpose of this study was to evaluate the safety and efficacy of a new combined method of Q-S laser-assisted tattoo removal. Ten patients with 13 professional, mostly mono-chromatic black tattoos were recruited. All tattoos received the same Q-S laser treatment sequence. An objective evaluation of tattoo clearing was assessed by careful analysis of a standardized collection of digital images taken from each tattoo, 2  months after each laser session, with the help of a custom-made pigment-fading percentage photographic ruler. The percentages of pigment clearance and side effects were evaluated by 4 indepen...
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research
Ultra-Violet (UV) radiation from sunlight is the main carcinogen driving keratinocyte cancers of the skin. The accumulation of UV-induced mutations on sun-exposed areas leads to field cancerisation. Knowing the regenerative property of the skin, we investigated if epidermal ablation removes mutations on the epidermis and allows less mutated cells from the deeper part of the skin to repopulate the ablated surface. Patients with history of multiple epidermal cancers were subjected to epidermal ablation on their forearms with three different depths of laser (600nm, 400nm and fractional laser).
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Source Type: research
This study enrolled hand scar patients who received treatment in our hospital between May 2018 and April 2019. Patients were assigned to undergo AFXL surgery based on their personal intents and condition, whereas the fractional laser was used for stiffness and abnormal texture. Outcomes were as follows: hand function was evaluated using the Michigan hand outcomes questionnaire; scar condition was evaluated using the Vancouver scar scale and UNC4P scar scale. Total 30 pediatric patients (mean age, 11.4 years) were eligible for the study and laser-treated scars were significantly improved in Michigan hand outcomes questionna...
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research
Vaccine. 2021 Aug 4:S0264-410X(21)00988-9. doi: 10.1016/j.vaccine.2021.07.083. Online ahead of print.ABSTRACTThe skin has been intensely investigated as a target tissue for immunization because it is populated by multiple types of antigen presenting cells. Directly addressing dendritic cells or Langerhans cells in vivo represents an attractive strategy for inducing T cell responses in cancer immunotherapy. We and others have studied fractional laser ablation as a novel method combining efficient delivery of macromolecules to the skin with an inherent adjuvant effect of laser illumination. In this proof of concept study, we...
Source: Vaccine - Category: Allergy & Immunology Authors: Source Type: research
Condition:   Wrinkle Interventions:   Procedure: Soluble Hyaluronic Acid Microneedle;   Procedure: Non-fractional laser Sponsor:   Shanghai Dermatology Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This study aimed to evaluate the clinical efficacy and safety of ASC-CM combined with 10,600  nm carbon dioxide fractional laser or microneedling for the treatment of refractory patch of AA. This retrospective study was based on evaluations of 14 patients with a refractory patch of AA treated with ASC-CM, combined with a 10,600 nm carbon dioxide fractional laser, or microneedling from Mar ch 2017 to August 2020. The efficacy of treatment was assessed by extents of hair regrowth percentages of involved areas. Of the 14 enrolled patients, 9 (64.3%) showed >  50% hair regrowth and 6 patients (42.9%)...
Source: Archives of Dermatological Research - Category: Dermatology Source Type: research
In conclusion, AFL and NI result in distinct cutaneous biodistribution patterns and pharmacokinetic profiles for BLM applied to in vivo skin. Evaluation of LSRs showed that both methods were similarly tolerable, and each method has potential for individualized approaches in a clinical setting.PMID:34121567 | DOI:10.1080/10717544.2021.1933649
Source: Drug Delivery - Category: Drugs & Pharmacology Authors: Source Type: research
CONCLUSIONS: When combined, the results obtained in this study regarding anisotropy, entropy and density tend to demonstrate that it is possible to achieve collagen remodeling with the use of lower power levels associated with stacked pulses.PMID:33978061 | DOI:10.1590/ACB360304
Source: Acta Cirurgica Brasileira - Category: Surgery Authors: Source Type: research
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