Most in U.S. Aren't Suitable Kidney Donors, Study Says

Title: Most in U.S. Aren't Suitable Kidney Donors, Study SaysCategory: Health NewsCreated: 11/14/2014 12:00:00 AMLast Editorial Review: 11/17/2014 12:00:00 AM
Source: MedicineNet Crohn's Disease General - Category: Gastroenterology Source Type: news

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Publication date: Available online 23 August 2019Source: Stem Cell ResearchAuthor(s): Lanzi Gaetana, Masneri Stefania, Ferraro Rosalba Monica, Genova Elena, Piovani Giovanna, Barisani Chiara, Pelin Marco, Stocco Gabriele, Decorti Giuliana, Bramuzzo Matteo, Giliani SilviaAbstractCrohn's disease is a debilitating and incurable chronic inflammatory bowel disease, affecting millions of individuals worldwide, with an increasing frequency. Surgery must be applicable in half of the cases often with a disabling course, and pharmacological treatments may have adverse complications. We generated three isogenic clones of iPSCs from p...
Source: Stem Cell Research - Category: Stem Cells Source Type: research
Authors: Krajewska JB, Pietruszka P, Tomczyk D, Chen C, Owczarek A, Karolewicz B, Czapor-Irzabek H, Gorniak A, Fichna J Abstract Crohn's Disease (CD), one of the types of inflammatory bowel disease, poses a significant challenge to modern healthcare. This condition severely impacts patients' quality of life, and its incidence is continuously rising. Despite constant research, current treatment options are limited and largely unsuccessful and result in serious side effects, therefore new therapy alternatives are needed. Liposomal formulation provides a new hope for disease management. In our study, we characterized ...
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
A Case of Bacteriologically Determined De NovoTuberculosis during Tumor Necrosis Factor-α Inhibitor Therapy. Intern Med. 2019 Aug 21;: Authors: Takahashi G, Kobayashi H, Saito Y, Ohsawa S, Suzuki K, Ishihara S, Hisada T Abstract A 58-year-old man with Crohn's disease received adalimumab for 13 months after screening results for tuberculosis were found to be negative. He was diagnosed with de novo mediastinal lymph-node tuberculosis, which was proved to be bacteriologically identical to that of an individual with smear positive lung tuberculosis by a variable number of tandem repeat analyses. Afte...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
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Source: Journal of Pediatric Gastroenterology and Nutrition - Category: Gastroenterology Tags: Case Report Source Type: research
Authors: Kim S, Kang Y, Park S, Koh H, Kim S Abstract BACKGROUND: It has been known that vitamin D level (serum 25[OH]D) has correlation with inflammatory bowel disease (IBD). The purpose of this study is to investigate changes of serum 25[OH]D in pediatric IBD patients according to the disease activity. METHODS: A total of 96 children and adolescent with IBD were enrolled in this retrospective study. Serologic inflammatory markers and clinical disease activity scores of the patients were collected, and their correlations with serum 25[OH]D were analyzed. Seasonal variations of serum 25[OH]D were also investiga...
Source: Journal of Korean Medical Science - Category: Biomedical Science Tags: J Korean Med Sci Source Type: research
Conclusions: Long diagnostic delay in IBD was mainly due to the longer delay in gastroenterologist consultation. Review of the referral system is needed to focus on measures to reduce long delays in diagnosis. The ileal location as a risk factor in CD and age older than 10 years as protective in UC should help recognition and early referral.
Source: The Saudi Journal of Gastroenterology - Category: Gastroenterology Authors: Source Type: research
Children with inflammatory bowel disease (IBD) may be at higher risk for psychiatric disorders and suicide attempt, according to a large, population-basedstudy published inJAMA Pediatrics.The risk for psychiatric disorders and suicide among children with IBD was greater when compared with siblings without IBD, indicating that the risk is likely related to IBD itself and not to genetic or environmental factors shared with siblings."Particularly concerning is the increased risk of suicide attempt," wrote Agnieszka Butwicka, M.D., Ph.D., of the Karolinska Institute in Sweden and colleagues. "Long-term psycholog...
Source: Psychiatr News - Category: Psychiatry Tags: ADHD anxiety autism Crohn's disease IBD inflammatory bowel disease mood disorders personality disorders suicide ulcerative colitis Source Type: research
Condition:   Crohn Disease Intervention:   Other: Soy based diet Sponsors:   Case Western Reserve University;   University of California, Davis;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   University Hospitals Cleveland Medical Center Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
The Crohn’s-like lymphoid reaction (CLR) to colorectal cancer (CRC), a CRC-specific ectopic lymphoid reaction, is thought to play an important role in the host response to CRC. CLR is characterized by peritumoral lymphocytic aggregates that are found at the advancing edge of the tumor. Spatial and molecular characterization of CLR within the tumor microenvironment (TME) have uncovered a spectrum of peritumoral lymphoid aggregates with varying levels of organization and maturation. In early stages of CLR development, CD4+ T-cells cluster predominantly with mature antigen presenting dendritic cells. As CLR matures, inc...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
We report a case of a 46-year-old Chinese male who presented with six months history of abdominal pain, weight loss and rectal bleeding. Diagnostic colonoscopy revealed multiple aphthous ulcers within the ileo-caecal region and distal transverse colon, separated by normal mucosa, mimicking skip lesions of Crohn's colitis. Computer topography (CT) scan of the abdomen showed multiple circumferential thickenings involving predominantly the right colon. A clinical diagnosis of colonic Crohn's disease with possible perforation was made. An extended right hemicolectomy was performed due to uncontrolled rectal bleeding. Histopath...
Source: Malaysian Journal of Pathology - Category: Pathology Tags: Malays J Pathol Source Type: research
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