Many Dialysis Patients Ill-Prepared for Emergencies, Study Says
Title: Many Dialysis Patients Ill-Prepared for Emergencies, Study SaysCategory: Health NewsCreated: 11/13/2014 12:00:00 AMLast Editorial Review: 11/14/2014 12:00:00 AM
Journal of Laparoendoscopic&Advanced Surgical Techniques, Ahead of Print.
Authors: Wu CQ, Lin QR, Ying SJ, Luo JK, Hong WJ, Lin ZJ, Jiang Y Abstract Aims The aryl hydrocarbon receptor (AhR) plays a pivotal role in regulating the innate and the acquired immune systems. The present study aimed to investigate the association of Crohn's disease (CD) with AhR polymorphisms in a cohort of patients from Southeast China. Methods An improved multiple ligase detection reaction technique was applied to examine the polymorphisms of rs2158041, rs2066853, and rs10249788 in 310 patients with CD and 573 controls. Results Compared to the controls, the variant allele (T) and genotype (CT+TT) of rs2158041 ...
Authors: Seyedian SS, Nokhostin F, Malamir MD Abstract Ulcerative colitis (UC) and Crohn's disease (CD) are classified as chronic inflammatory bowel diseases (IBD) which have similar symptoms and lead to digestive disorders and inflammation in the digestive system. The reason why they occur is still a mystery. A number of factors can be attributed to the prevalence of CD and UC, some of which include geographical location, inappropriate diet, genetics, and inappropriate immune response. Both diseases are more often diagnosed in urban areas compared to rural areas and both have their own challenges and side effects,...
American Journal of Roentgenology, Ahead of Print.
Condition: Steroid Dependent Crohn's Disease Interventions: Drug: Cannabidiol , synthetic form; Drug: Placebo Sponsor: Stero Biotechs Ltd. Recruiting
Authors: Egal A, London J, Lidove O, Atienza P, Etienney I Abstract Numerous systemic diseases (vasculitis, connective tissue disease or sarcoidosis) can display an involvement of the perianal skin, the rectum and/or the anus. Such knowledge is important in order to treat these complications specifically when possible. Lesions of the anorectum arising from systemic diseases can sometimes cause perforations in the peritoneal cavity (if concerning the higher portion of the rectum) and/or fistulization to the anal margin. Differential diagnosis, mostly infectious or inflammatory (Crohn's disease) must be ruled out in ...
This study examined the effectiveness and safety of long-term vedolizumab maintenance therapy in patients with moderate-to-severe active ulcerative colitis and Crohn's disease.Alimentary Pharmacology &Therapeutics
Conclusion: Prior appendectomy is a risk factor for the onset of CD. However, the appendectomy rate only increased for a short duration before CD diagnosis, likely reflecting a diagnostic bias. Prior appendectomy did not influence the features or course of CD. PMID: 31396275 [PubMed]
CONCLUSION: Guselkumab represents a promising therapeutic option for recalcitrant HS patients with inflammatory comorbidities in which IL-23 plays a role. PMID: 31389737 [PubMed - as supplied by publisher]