Relationship between Serum IGF-I and Skeletal Muscle IGF-I mRNA Expression to Phosphocreatine Recovery after Exercise in Obese Men with Reduced GH.

Conclusion: These data demonstrate a novel association of skeletal muscle mitochondria with muscle IGF-I mRNA expression, but independent of serum IGF-1 concentrations. PMID: 25375982 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research

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AbstractAimTo analyze the outcomes of component separation techniques (CST) to treat incisional hernias (IH) in a large multicenter cohort of patients.MethodsAll IH repair using CST, registered in EVEREG from July 2012 to December 2019, were included. Data on the pre-operative patient characteristics and comorbidities, IH characteristics, surgical technique, complications, and recurrence were collected. Outcomes between anterior (ACS) and posterior component separation (PCS) techniques were compared. Risk factors for complications and recurrences were analyzed.ResultsDuring the study period, 1536 patients underwent CST (45...
Source: Hernia - Category: Sports Medicine Source Type: research
Cell Mol Immunol. 2021 Nov 26. doi: 10.1038/s41423-021-00804-7. Online ahead of print.ABSTRACTGlucose is a vital source of energy for all mammals. The balance between glucose uptake, metabolism and storage determines the energy status of an individual, and perturbations in this balance can lead to metabolic diseases. The maintenance of organismal glucose metabolism is a complex process that involves multiple tissues, including adipose tissue, which is an endocrine and energy storage organ that is critical for the regulation of systemic metabolism. Adipose tissue consists of an array of different cell types, including speci...
Source: Cellular and Molecular Immunology - Category: Molecular Biology Authors: Source Type: research
AbstractIntroductionGestational diabetes mellitus (GDM) significantly increases maternal and fetal health risks, but factors predictive of GDM are poorly understood.ObjectivesPlasma metabolomics analyses were conducted in early pregnancy to identify potential metabolites associated with prediction of GDM.MethodsSixty-eight pregnant women with overweight/obesity from a clinical trial of a lifestyle intervention were included. Participants who developed GDM (n  = 34; GDM group) were matched on treatment group, age, body mass index, and ethnicity with those who did not develop GDM (n = 34; Non-GDM ...
Source: Metabolomics - Category: Biology Source Type: research
Reporting high-quality bariatric surgery outcomes depends on participant attrition and level of study participation among enrolled participants.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Original articles Source Type: research
Pre-surgical psychopathology does not consistently predict post-surgical outcomes in patients who undergo metabolic and bariatric (MBS) surgery. Individuals with elevated pre-MBS psychopathology may be less likely to undergo surgery, which may create a floor effect due to the limited range of scores on measures of psychopathology included in post-surgical analyses, thereby decreasing power to detect clinically significant differences between groups.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Integrated Health Article Source Type: research
AbstractIodine is an essential component of the thyroid hormones, thyroxine and triiodothyronine. Its availability strictly depends on iodine content of foods, which may vary from very low to very high. Inadequate iodine intake (deficiency or excess) may affect thyroid function resulting in hypothyroidism or hyperthyroidism. Based on median urinary iodine concentrations, epidemiological criteria have been established for the categorization and monitoring of nutritional iodine status of a population (or subgroups of populations). Additional methods for iodine intake assessment include measurement of thyroid size (by thyroid...
Source: Thyroid Research - Category: Endocrinology Source Type: research
We examined the effects of maternal active and secondhand smoking during pregnancy on childhood obesity in a large population-based cohort. A nested case–control study originating from the Japan Environment and Children’s Study was performed. The maternal smoking status was collected via self-administered questionnaires during mid/late pregnancy. Obesity in children was determined based on BMI measured at 3 years of age. In total, 4875 cases and 19,491 controls were included in the analyses. Conditional logistic regression models with a significance level of 5% (two-tailed test) were used to test the as...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
IJERPH, Vol. 18, Pages 12501: Assessment of Dysfunctional Movements and Asymmetries in Children and Adolescents Using the Functional Movement Screen—A Narrative Review International Journal of Environmental Research and Public Health doi: 10.3390/ijerph182312501 Authors: Pat R. Vehrs Martina Uvacsek Aaron W. Johnson The Functional Movement Screen (FMS) is a screening tool that identifies dysfunctional movements in seven test items requiring an interplay of cognitive, perceptual, proprioceptive, and motor functions that involve muscular strength/endurance, flexibility, mobility, coordination, and balance. ...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Review Source Type: research
Rita Polito Polycystic ovary syndrome (PCOS) is a commonly occurring endocrine disorder characterized by hirsutism, anovulation, and polycystic ovaries. Often comorbid with insulin resistance, dyslipidemia, and obesity, it also carries significant risk for the development of cardiovascular and metabolic sequelae, including diabetes and metabolic syndrome. The relationship between central obesity and the development of insulin resistance is widely verified. Adipose tissue excess and the coexistent dysregulation of adipocyte functions directly contribute to the pathogenesis of the metabolic complications observed in wo...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Overconsumption of processed foods has led to an increase in chronic diet-related diseases such obesity and type 2 diabetes. Although diets high in fresh fruits and vegetables are linked with healthier outcome...
Source: BMC Research Notes - Category: Research Authors: Tags: Research note Source Type: research
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