Donna Altenpohl on Ebola

Ebola response is a model of collaboration The constant stream of photos and reports about Ebola from West Africa tragically illustrate the speed at which disease can spread, devastating communities and reshaping daily life. GSK is working with many partners at an unprecedented speed and with passionate focus to try to develop a vaccine to limit the total number of deaths from this epidemic and future outbreaks. While the current crisis is our focus, there also are lessons for the future: US health and security can be threatened by events half a world away and the global community is not fully prepared for such disease outbreaks. We commend world health authorities, governments, public and private entities for their commitment and collaboration to aggressively meet this urgent health need, but we acknowledge the need to improve our preparations to respond to other global health crises before the next outbreak or epidemic. Americans have lived through such threats, including the anthrax-containing letters mailed to Congressional offices and the 2009 H1N1 influenza pandemic that caused more than 10,000 deaths.  We must move now to prevent and contain future epidemics, whether it is Ebola or another emerging infectious disease. The World Health Organization (WHO) convened a meeting last week with governments, agencies, charities and companies, including GSK, to agree how to accelerate testing and deployment of vaccines that could restrict the evolution of this epidemic. GSK...
Source: PHRMA - Category: Pharmaceuticals Authors: Source Type: news

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CONCLUSIONS: Genomic analysis of three recent ZIKV isolates revealed some nonsynonymous substitutions, which could have an impact on the viral fitness in mammalian and insect cells. PMID: 31432892 [PubMed - in process]
Source: Memorias do Instituto Oswaldo Cruz - Category: Infectious Diseases Authors: Tags: Mem Inst Oswaldo Cruz Source Type: research
This article discusses HIV epidemiology, describes the current state of HIV treatment and prevention, and highlights common comorbidities often seen in PLWH who are over age 50.
Source: AJN - Category: Nursing Tags: Feature Articles Source Type: research
No abstract available
Source: AJN - Category: Nursing Tags: Feature Articles Source Type: research
ConclusionThe results of this study reveal thatEnterobacter spp. isolates from hospital settings are both resistant to clinically-used antibiotics and tolerant to biocides. Biocide tolerance could be an advantage for antibiotic-resistant strains in hospitals.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Conclusion: The perception of health risk of contracting influenza and a primary healthcare physicians' recommendation played an important role in shaping participants' decisions towards vaccination. Primary healthcare physicians are invited to assess and if necessary adjust inappropriate prevention behaviour through their everyday patient consultations as well as add to the knowledge about influenza severity and influenza vaccination benefits to their patients. PMID: 31431093 [PubMed - as supplied by publisher]
Source: European Journal of General Practice - Category: Primary Care Tags: Eur J Gen Pract Source Type: research
Publication date: Available online 23 August 2019Source: Nano TodayAuthor(s): Rein Verbeke, Ine Lentacker, Stefaan C. De Smedt, Heleen DewitteAbstractIn the early nineties, pioneering steps were taken in the use of mRNA as a therapeutic tool for vaccination. In the following decades, an improved understanding of the mRNA pharmacology, together with novel insights in immunology have positioned mRNA-based technologies as next-generation vaccines. This review outlines the history and current state-of-the-art in mRNA vaccination, while presenting an immunological view on mRNA vaccine development. As such, we highlight the chal...
Source: Nano Today - Category: Nanotechnology Source Type: research
This study examined the effect of NH3 on the immune response to infectious bronchitis virus (IBV) vaccination and protection against homologous serotype challenge in commercial broiler chickens. One-day-old chicks were administered IBV vaccine and exposed to 30-60 ppm of NH3. At 28 DOA, birds were challenged oculonasally with a pathogenic homologous IBV, and protection was measured by viral detection, clinical signs, ciliostasis, and presence of airsacculitis. IBV-specific serum IgG and lacrimal fluid IgA titers, as well as Harderian gland (HG) immune cell phenotypes, were evaluated. Ammonia exposure was associated ...
Source: Veterinary Immunology and Immunopathology - Category: Veterinary Research Source Type: research
Source: American Journal of Health Behavior - Category: Psychiatry & Psychology Authors: Source Type: research
With tensions over trade with China escalating, President Donald Trump said on Friday that he is “ordering” the U.S. postal service and express shipping companies to “SEARCH FOR &REFUSE all deliveries of fentanyl,” a deadly synthetic opioid. American officials have long blamed China for the influx of fentanyl and related drugs reaching U.S. borders — sent directly and trafficked via other countries — while federal efforts to limit (if not stop outright) their import have long been underway. ….your companies HOME and making your products in the USA. I will be responding to C...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized China Drugs White House Source Type: news
Source: BMJ Comments - Category: General Medicine Source Type: forums
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