Donna Altenpohl on Ebola

Ebola response is a model of collaboration The constant stream of photos and reports about Ebola from West Africa tragically illustrate the speed at which disease can spread, devastating communities and reshaping daily life. GSK is working with many partners at an unprecedented speed and with passionate focus to try to develop a vaccine to limit the total number of deaths from this epidemic and future outbreaks. While the current crisis is our focus, there also are lessons for the future: US health and security can be threatened by events half a world away and the global community is not fully prepared for such disease outbreaks. We commend world health authorities, governments, public and private entities for their commitment and collaboration to aggressively meet this urgent health need, but we acknowledge the need to improve our preparations to respond to other global health crises before the next outbreak or epidemic. Americans have lived through such threats, including the anthrax-containing letters mailed to Congressional offices and the 2009 H1N1 influenza pandemic that caused more than 10,000 deaths.  We must move now to prevent and contain future epidemics, whether it is Ebola or another emerging infectious disease. The World Health Organization (WHO) convened a meeting last week with governments, agencies, charities and companies, including GSK, to agree how to accelerate testing and deployment of vaccines that could restrict the evolution of this epidemic. GSK...
Source: PHRMA - Category: Pharmaceuticals Authors: Source Type: news

Related Links:

Authors: Abellán JM, Jimenez-Gomez D Abstract A large part of morbimortality is caused by lifestyle habits and modifiable risk factors. A promising strategy to promote the change of such factors is the implementation of public health interventions based on behavioral economics, a discipline that combines psychological and economic principles. In the present article, we focus on a type of intervention known as "nudge" (that has been translated into Spanish as empujón or acicate), that changes behaviour without limiting the individual's choice. We analyze the properties that characterize nudge...
Source: Gaceta Sanitaria - Category: International Medicine & Public Health Tags: Gac Sanit Source Type: research
Publication date: 21 August 2019Source: Neuron, Volume 103, Issue 4Author(s): Matthew P. WalkerWe are suffering a global sleep-loss epidemic. The health consequences within an individual are well characterized. But does society suffer just as much? Here, I discuss how insufficient sleep erodes our societal fabric as much as it does our biological fabric, and offer some prescriptive remedies.
Source: Neuron - Category: Neuroscience Source Type: research
Authors: Hozbor D Abstract Effective diphtheria, tetanus toxoids, whole-cell pertussis (wP) vaccines were used for massive immunization in the 1950s. The broad use of these vaccines significantly reduced the morbidity and mortality associated with pertussis. Because of reports on the induction of adverse reactions, less-reactogenic acellular vaccines (aP) were later developed and in many countries, especially the industrialized ones, the use of wP was changed to aP. For many years, the situation of pertussis seemed to be controlled with the use of these vaccines, however in the last decades the number of pertussis ...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Authors: Gillard J, van Schuppen E, Diavatopoulos DA Abstract Despite widespread vaccination, B. pertussis remains one of the least controlled vaccine-preventable diseases. Although it is well known that acellular and whole cell pertussis vaccines induce distinct immune functionalities in memory cells, much less is known about the role of innate immunity in this process. In this review, we provide an overview of the known differences and similarities in innate receptors, innate immune cells and inflammatory signalling pathways induced by the pertussis vaccines either licensed or in development and compare this to p...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
We present the results of a social programme facilitating access to physical activities for vulnerable children in Italy. 311 school-age children enrolled in the programme between 2015 and 2017 were assessed for health and lifestyle, anthropometric and nutritional status. Data were compared by origin (Italians vs. immigrants) and then immigrants were split into sub-groups: first- and second-generation. Poor socio-economic status exposed children to a lack of access to health services, and drove imbalanced eating behaviour. 20.8% of children were not registered with the National Health Services (immigrants p 
Source: International Journal of Food Sciences and Nutrition - Category: Nutrition Tags: Int J Food Sci Nutr Source Type: research
Publication date: Available online 21 August 2019Source: Preventive Veterinary MedicineAuthor(s): T.G. Baraldi, N.R.N. Cruz, D.A. Pereira, J.V.B. Galdeano, I.R.H. Gatto, A.F.D. Silva, A. Panzardi, D.C.L. Linhares, L.A. Mathias, L.G. de OliveiraAbstractA study was conducted on 21 pig herds using one-site production system in the southeast region of Brazil to assess the relationships among serological results for primary pathogens involved in respiratory diseases (Actinobacillus pleuropneumoniae, App; Mycoplasma hyopneumoniae, Mhyo; and swine influenza virus, SIV), cough index, pneumonia index, pleuritis and herd characteris...
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
In conclusion, using a simple, fast, and inexpensive detection method, such as LAMP, especially in endemic regions or in an outbreak to control spreading of pathogens, is very important for public health.
Source: Journal of Microbiological Methods - Category: Microbiology Source Type: research
The New England Journal of Medicine, to their credit,has several open-access essays on the environmental crisis. A good part of the value-added from these is that they demonstrate the synergy among some important issues that aren't often considered together, and don't get a lot of attention in the corporate media.Sorenson and Gracia-Trebenino discuss an epidemic that is largely ignored in the United States. Agricultural workers in tropical climates are experiencing radical increases in the incidence of chronic kidney disease and renal failure. While the cause is not fully understood, it appears to be linked to rising tempe...
Source: Stayin' Alive - Category: American Health Source Type: blogs
ConclusionThis study demonstrated that in-line PAT can be used to monitor particle size and chemical composition for the various stages of adjuvant manufacturing from raw materials through intermediate to final adjuvant product stage. Similar approaches can be utilized to help assess lot-to-lot consistency during adjuvant manufacturing and vaccine product development. Moreover, the use of in-line PAT is highly conductive to advanced manufacturing strategies such as real-time product release testing and automated processes of the future.Graphical Abstract
Source: Computational and Structural Biotechnology Journal - Category: Biotechnology Source Type: research
In this study, nine truncated CyHV-2 membrane glycoproteins (ORF25, ORF25C, ORF25D, ORF30, ORF124, ORF131, ORF136, ORF142A, ORF146) and a GFP reporter protein were respectively expressed using baculovirus surface displaying system. Western blot showed that the proteins were successfully packaged in the recombinant virus particles. In baculovirus transduced gibel carp kidney cells, the target proteins were expressed and displayed on the fish cell surface. Healthy gibel carp were immunized by immersion with the recombinant baculoviruses and the fish treated with phosphate-buffered saline (PBS) were served as mock group. The ...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
More News: African Health | Anthrax | Anthrax Vaccine | Department of Health | Ebola | Ebola Vaccine | Epidemics | Epidemiology | Flu Pandemic | Funding | Government | H1N1 | Health | Infectious Diseases | Influenza | Influenza Vaccine | International Medicine & Public Health | Learning | Lessons | Outbreaks | Pandemics | Partnerships | Pharmaceuticals | Politics | Superbugs | Swine Flu (H1N1) Vaccine | Universities & Medical Training | Vaccines | WHO