The great imitator revisited: the spectrum of atypical cutaneous manifestations of secondary syphilis

Abstract Syphilis is a well‐known sexually transmitted infection infamous for its protean cutaneous manifestations. Over the last decade, the rate of infection in the USA has risen, particularly among human immunodeficiency virus (HIV)‐infected individuals and certain ethnic groups. Although the primary chancre developing at the site of inoculation usually has typical and well‐characterized features, cutaneous manifestations of secondary syphilis span a wide spectrum and mimic those of other dermatoses. This may be particularly evident in patients with HIV. Such deviations from the expected typical papulosquamous eruption may present a diagnostic challenge and delay diagnosis and therapy. Given the increasing incidence of syphilis among the immunosuppressed patient population, recognition of atypical cutaneous manifestations is critical for adequate management. We review a range of cutaneous manifestations of secondary syphilis and the skin diseases it may mimic.
Source: International Journal of Dermatology - Category: Dermatology Authors: Tags: Review Source Type: research

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(Natural News) According to the World Health Organization (WHO), more than one million cases of sexually transmitted infections (STIs) are contracted every day, with chlamydia, gonorrhea, trichomoniasis and syphilis infections being the most worrisome. The WHO report, based on 2016 global data, showed that there were 156 million new cases of trichomoniasis, 127 million cases of...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Authors: Rob F, Jůzlová K, Kružicová Z, Vaňousová D, Lásiková Š, Sýkorová B, Machala L, Rozsypal H, Veselý D, Zákoucká H, Hercogová J Abstract OBJECTIVES: The aim of the study was to determine the prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae co-infections among patients with newly diagnosed syphilis. METHODS: In patients with any stage of newly diagnosed syphilis swabs were performed from urethra, rectum, pharynx and cervix according to the gender and type of sexual intercourse. From these smears standard val...
Source: Central European Journal of Public Health - Category: International Medicine & Public Health Tags: Cent Eur J Public Health Source Type: research
CONCLUSION: This case of "early" syphilis illustrates a change in the French epidemiology of sexually transmitted diseases (STIs). STIs currently affect very young and previously unexposed metropolitan French populations. These infections are increasing in teenagers due to an increase in high-risk sexual behavior associated with a lack of knowledge of STIs. This case is a reminder of the current decline in the level of knowledge about STIs among teenagers as compared to young people of the same age in the 1990s. PMID: 31955971 [PubMed - as supplied by publisher]
Source: Annales de Dermatologie et de Cenereologie - Category: Dermatology Authors: Tags: Ann Dermatol Venereol Source Type: research
Conclusions This survey collected important information on PHL STD laboratory testing practices. Capacity for important reference laboratory testing, such as GC culture and antimicrobial susceptibility, are needed to support STD programs. Public health laboratories play a key role in STD screening, surveillance, and prevention by offering test methods that are not available at commercial laboratories. Funding constraints affect the resources available for STD screening and surveillance, and thus, it is important to continue to monitor testing practices and the capacity of PHLs to test for STDs.
Source: Sexually Transmitted Diseases - Category: Sexual Medicine Tags: Original Studies Source Type: research
The objectives of this study were to measure the lifetime prevalence of syphilis and sociodemographic and behavior correlates of antibody positivity among female prisoners in Brazil. Methods We conducted a cross-sectional survey of 1327 incarcerated women in 2014 to 2015 sampled through a multistage cluster design to represent the penitentiary system throughout Brazil. A rapid treponemal antibody test approved by the Ministry of Health (Rapid Test DPP Sífilis Bio-Manguinhos) was used to detect lifetime history of infection. Analyses were adjusted using weights based on the inverse of the product of the probabilit...
Source: Sexually Transmitted Diseases - Category: Sexual Medicine Tags: Original Studies Source Type: research
Objectives Male and transgender women sex workers (TSWs) are vulnerable for sexually transmitted infections (STIs) and human immunodeficiency virus (HIV), and substance use might be a relevant contributing factor. We assessed sociodemographic characteristics and substance use among sex workers; divided into 3 groups: Transgender women sex workers, male sex workers who have sex with men only or also with females (MSW-M), male sex workers who have sex with females only (MSW-F). Methods A survey on substance use and sexual (risk) behavior was offered during routine STI screening at the Prostitution and Health Centre (P&G...
Source: Sexually Transmitted Diseases - Category: Sexual Medicine Tags: Original Studies Source Type: research
(Natural News) According to the World Health Organization (WHO), more than one million cases of sexually transmitted infections (STIs) are contracted every day, with chlamydia, gonorrhea, trichomoniasis and syphilis infections being the most worrisome. The WHO report, based on 2016 global data, showed that there were 156 million new cases of trichomoniasis, 127 million cases...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Sexually transmitted infections (STIs) are a group of infectious diseases that can cause acute illness and life-long health effects. Nearly half of all diagnosed cases occur in adolescents and young adults, ages 15-24. The American Academy of Pediatrics and Centers for Disease Control provide guidelines for routine STI screening for all sexually active adolescents. Despite these recommendations, screening rates in adolescents admitted to our hospital are low. The purpose of this study is to use quality improvement methodology to improve screening for HIV, gonorrhea, chlamydia, and syphilis in adolescent patients in an inpatient setting.
Source: Journal of Adolescent Health - Category: Child Development Authors: Source Type: research
AbstractGlobally, young people in sub-Saharan Africa continue to be the population at the greatest risk for sexually transmitted infections (STIs) such as HIV and AIDS, Syphilis, and Gonorrhoea. Research has shown significant relationship between young peoples risky sexual behaviours and their vulnerability to these STIs. The study examined risky sexual behaviours among the youth in Ghana and Kenya in relation to socio-demographic characteristics. The paper uses data from the 2014 Demographic and Health Surveys of Ghana and Kenya. Young people between the ages of 15 to 24  years who were not married or living with a m...
Source: Journal of Community Health - Category: International Medicine & Public Health Source Type: research
Purpose of review The combined incidence of chlamydia, gonorrhoea and syphilis in MSM PrEP (preexposure prophylaxis) cohorts now frequently exceeds 100 per 100 person years. The efficacy of antiretroviral PrEP in reducing HIV transmission has led to efforts to find similar biomedical ways reduce sexually transmitted infection (STI) incidence. We review the recent evidence for these and other strategies. Recent findings Doxycycline PrEP/postexposure prophylaxis has been shown to reduce the incidence of syphilis and chlamydia but not gonorrhoea. A meningococcal vaccine has been found to result in a lower incidence of go...
Source: Current Opinion in Infectious Diseases - Category: Infectious Diseases Tags: STD: Edited by Joseph A. Duncan Source Type: research
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