p53 Mutation in the Genesis of Metastasis.
p53 Mutation in the Genesis of Metastasis. Subcell Biochem. 2014;85:105-17 Authors: Yeudall WA Abstract Development of metastatic cancer is a complex series of events that includes genesis of tumor-related vascular and lymphatic systems, enhanced cellular motility, and the capacity to invade and survive at distant sites, as well as evasion of host defences. The wild-type p53 protein plays key roles in controlling these facets of tumor progression, and loss of normal p53 function can be sufficient to predispose tumor cells to gain metastatic properties. In contrast, dominant p53 mutants that have gained oncogenic functions can actively drive metastasis through a variety of mechanisms. This chapter aims to highlight these processes. PMID: 25201191 [PubMed - in process]
A computer-based simulation model projected that CT lung screening in several...Read more on AuntMinnie.comRelated Reading: Biennial follow-up exams prove safe for CT lung screening Lung cancer imaging on the upswing in China CT lung screening spots cancers earlier in China CT lung screening cuts cancer mortality 51% in Japan CT lung screening may benefit racial minorities most
For its fiscal year that ended June 30, the Little Rock cancer treatment provider reported a $3.5 million operating income before depreciation.
ConclusionsOverall HCAHPS satisfaction scores following lung resection for cancer were high and negatively associated with increasing length of stay. Patient satisfaction may be impacted more by the perception of effective communication during prolonged hospitalizations than by complications.