EU monitoring health risks

The European Food Safety Authority invites tenders for generating, collecting, collating, synthesising and analysing evidence supporting preparatory work for evidence-based scientific assessment in EFSA. Tenders may be submitted for one of the more of the following lots: animal health and welfare, chemicals in the food chain, environmental risks, microbiological and zoonotic agents, human nutrition and plant health. The total estimated value of all six lots is €8 million. The deadline for applications is 30 September 2014. For further information, please contact the European Food Safety Authority’s Planning and Monitoring Team at rasa.procurement@efsa.europa.eu.
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

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CONCLUSIONS: The higher frequency of AII sub-assemblage suggests that anthroponotic transmission is more common in Salvador, but that zoonotic transmission pathways are also present and a change in susceptibility to different molecular patterns of Giardia may occur during child growth. PMID: 33030834 [PubMed - as supplied by publisher]
Source: Biomedica : Revista del Instituto Nacional de Salud - Category: International Medicine & Public Health Tags: Biomedica Source Type: research
Coronaviruses have caused several zoonotic infections in the past two decades, leading to significant morbidity and mortality globally. Balanced regulation of cell death and inflammatory immune responses is essential to promote protection against coronavirus infection; however, the underlying mechanisms that control these processes remain to be resolved. Here we demonstrate that infection with the murine coronavirus mouse hepatitis virus (MHV) activated the NLRP3 inflammasome and inflammatory cell death in the form of PANoptosis. Deleting NLRP3 inflammasome components or the downstream cell death executioner gasdermin D (G...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Microbiology Source Type: research
Chagas disease is a zoonotic infection caused by the parasite Trypanosoma cruzi, which affects an estimated 8 –11 million people globally. Chagas disease is almost always associated with poverty in rural areas and...
Source: BMC Infectious Diseases - Category: Infectious Diseases Authors: Tags: Research article Source Type: research
AbstractRabies is an important zoonotic disease in Iran. Autophagy is a process that maintains homeostasis and can be used as an innate defense mechanism against viruses. Apoptosis is the process of programmed cell death induced by physiological and pathological conditions. The crosstalk of autophagy and apoptosis plays a key role in rabies virus infection. In the current study, NMRI mice intra-cranially received 3-Methyl Adenine (3-MA), rapamycin, street rabies virus (SRABV) and drugs plus SRABV. SRABV andMap1lc3,Beclin-1,Atg5 gene expression were assayed by real-time PCR. Immunohistochemistry was carried out via LC3 prot...
Source: Archives of Virology - Category: Virology Source Type: research
éter Pankovics Hepatitis E virus (HEV) (family Hepeviridae) is one of the most common human pathogens, causing acute hepatitis and an increasingly recognized etiological agent in chronic hepatitis and extrahepatic manifestations. Recent studies reported that not only are the classical members of the species Orthohepevirus A (HEV-A) pathogenic to humans but a genetically highly divergent rat origin hepevirus (HEV-C1) in species Orthohepevirus C (HEV-C) is also able to cause zoonotic infection and symptomatic disease (hepatitis) in humans. This review summarizes the current knowledge of hepeviruses in rodents with...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Coronavirus (CoV) outbreaks have recently emerged as a global public health threat due to their exceptional zoonotic potential — a feature arising from their ability to infect a diverse range of potential hosts combined with their high capacity for mutation and recombination. After Severe Acute Respiratory Syndrome (SARS) CoV-1 in 2003 and Middle East Respiratory Syndrome (MERS) CoV in 2012, with the current SARS-CoV-2 pandemic we are now in the midst of the third deadly international CoV outbreak in less than 20 years. Coronavirus outbreaks present a critical threat to global public health and an urgent necessity fo...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
In this study, 16S rRNA gene sequencing, combined with metagenomic sequencing approach as well as ultraperformance liquid chromatography–mass spectrometry metabolic profiling, was applied to demonstrate changes in the gut microbiome community structure during schistosomiasis progression, the functional interactions between the gut bacteria and S. japonicum infection in BALB/c mice, and the dynamic metabolite changes of the host. The results showed that both gut microbiome and the metabolites were significantly altered at different time points after the infection. Decrease in richness and diversity as well as differed...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Most vector-borne pathogens cause zoonotic diseases. These zoonoses often have wild animal reservoirs that play a significant role in disease epidemiology. However, pet animals have also been implicated in tra...
Source: BMC Veterinary Research - Category: Veterinary Research Authors: Tags: Research article Source Type: research
Publication date: Available online 6 October 2020Source: IDCasesAuthor(s): Franklin E. Claro-Almea, Lourdes A. Delgado-Noguera, Ana Motaban, Mercedes España, Jacobus H. de Waard
Source: IDCases - Category: Infectious Diseases Source Type: research
Contributors : Nicholas M Negretti ; Yinyin Ye ; Lais M Malavasi ; Swechha M Pokharel ; Steven Huynh ; Susan Noh ; Christopher R Gourley ; Claude A Ragle ; Santanu Bose ; Torey Looft ; Craig T Parker ; Geremy Clair ; Joshua N Adkins ; Michael E KonkelSeries Type : Expression profiling by high throughput sequencingOrganism : Campylobacter jejuniThe symptoms of infectious diarrheal disease are mediated by the interplay between the host and pathogen. Campylobacter jejuni is the leading bacterial cause of diarrhea worldwide due to its near-ubiquitous zoonotic association with poultry. One of the outstanding questions is what f...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Campylobacter jejuni Source Type: research
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