Bizarre parasite from the Jurassic

(University of Bonn) Around 165 million years ago, a spectacular parasite was at home in the freshwater lakes of present-day Inner Mongolia, China: A fly larva with a thorax formed entirely like a sucking plate. With it, the animal could adhere to salamanders and suck their blood with its mouthparts formed like a sting. To date no insect is known that is equipped with a similar specialized design. The international scientific team is now presenting its findings in the journal 'eLIFE.'
Source: EurekAlert! - Biology - Category: Biology Source Type: news

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nte-Sucre A Abstract Cell-cell interaction and active migration (and invasion) of parasites into skin host-cell(s) are key steps for successful infection by Leishmania. Chemotaxis constitutes a primordial chapter of Leishmania-host cell interaction, potentially modulated by neuropeptides released into the skin due, for example, to the noxious stimuli represented by the insect bite. Herein we have evaluated in vitro the effect of sensory (Substance P, SP) and autonomic (Vasoactive Intestinal Peptide, VIP, and Neuropeptide Y, NPY) neuropeptides on parasite taxis, and investigated the potential modulatory effect of S...
Source: Experimental Parasitology - Category: Parasitology Authors: Tags: Exp Parasitol Source Type: research
This study highlights the role of STING-dependent pathways response to microsporidia in silkworm, Bombyx mori. PMID: 32916206 [PubMed - as supplied by publisher]
Source: Developmental and Comparative Immunology - Category: Allergy & Immunology Authors: Tags: Dev Comp Immunol Source Type: research
Conclusion: Public education and increasing the knowledge of people can lead to successful management, prevention and elimination of this nuisance pest. PMID: 32766346 [PubMed]
Source: Iranian Journal of Arthropod-Borne Diseases - Category: Infectious Diseases Tags: J Arthropod Borne Dis Source Type: research
This study sheds important new light on the molecular composition of the crystalloid, an enigmatic parasite organelle that is essential for sporozoite formation and transmission from the insect to the vertebrate host. Our findings provide new mechanistic insight into how proteins are delivered to the crystalloid, and indicate that the molecular mechanisms that underlie crystalloid function are complex, involving multiple protein families unique to Plasmodium and closely related organisms. The many new crystalloid proteins identified will form a useful starting point for future studies aimed at unravelling how the crystallo...
Source: Journal of Proteomics - Category: Biochemistry Authors: Tags: J Proteomics Source Type: research
Insect experts say people should calm down about the big bug with the nickname “murder hornet” — unless you are a beekeeper or a honeybee. The Asian giant hornets found in Washington state that grabbed headlines this week aren’t big killers of humans, although it does happen on rare occasions. But the world’s largest hornets do decapitate entire hives of honeybees, and that crucial food pollinator is already in big trouble. Numerous bug experts told The Associated Press that what they call hornet “hype” reminds them of the 1970s public scare when Africanized honeybees, nicknamed &l...
Source: TIME: Science - Category: Science Authors: Tags: Uncategorized Environment News Desk wire Source Type: news
There are several unmet needs in modern immunology. Among them, vaccines against parasitic diseases and chronic infections lead. Trypanosoma cruzi, the causative agent of Chagas disease, is an excellent example of a silent parasitic invasion that affects millions of people worldwide due to its progression into the symptomatic chronic phase of infection. In search for novel vaccine candidates, we have previously introduced Traspain, an engineered trivalent immunogen that was designed to address some of the known mechanisms of T. cruzi immune evasion. Here, we analyzed its performance in different DNA prime/protein boost pro...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Answer toParasite Case of the Week 568: Pseudoscorpion or false scorporion, not a human parasite.This fun little arthropod is occasionally submitted to the clinical laboratory for identification, and may be mistaken as a true scorpion. While both scorpions and pseudoscorpions are arachnids, pseudoscorpions are very small (1 cm or less in length) andlack a tail with a stinger. As sylvie g and Santiago note, pseudoscorpions can occasionally be found in the house, but they don't bite or sting humans, and instead feed on other small arthropods such as booklice.Thanks again to Old One and his son for the donation of the cool animated illustration.
Source: Creepy Dreadful Wonderful Parasites - Category: Parasitology Source Type: blogs
Toxoplasma gondii is an obligate protozoan parasite that naturally infects all mammals, where it alters the host environment to establish chronic infection. Wang and colleagues uncover a new role for the T. gondii protein GRA15 in inducing an anti-parasite response via the interferon stimulator STING. This parasite-driven host defense limits Toxoplasma replication while maintaining host survival, creating an ideal niche for the establishment of latency.
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Editors ' Picks Highlights Source Type: research
This study was supported in part by the Projects: Redes Internacionales (REDI170651) (to AH and MI); Proyecto interno Universidad Autónoma de Chile (DIUA 134-2018) and by the Pilot Research Grant (PP-1805-30965) from the National Multiple Sclerosis Society (to AH); Proyecto Genera-Autónoma N°UA 17-04 and FONDECYT de Inicio N° 11160592, CONICYT (to NE) and Proyecto Vicerrectoría de Investigación, Pontificia Universidad Católica de Chile Puente P1802 (to CL). Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or fina...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
In conclusion, we hope that this review brings about a new and more in-depth understanding of the part that Leishmania exosomes and various infectious agents play in the context of host-parasite interactions, with a particular focus on the establishment of infection. Future research in this field of investigations is critical for the development of new vaccine and diagnostic tools. Author Contributions The first draft was done by MO. AF and GD added new information. Funding Research in MO laboratory is supported by the Canadian Institute of Health Research (grant number: PJT-159765) and the Natural Sciences and Enginee...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
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