Heroin Epidemic Is Driving A Spike In Hepatitis C Cases, CDC Says

From 2010 to 2015, the number of new infections leaped nearly 300 percent, according to the Centers for Disease Control and Prevention. And researchers appear confident of the cause.(Image credit: Spencer Platt/Getty Images)
Source: NPR Health and Science - Category: Consumer Health News Authors: Source Type: news

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The opioid epidemic in the U.S. is driving a simultaneous epidemic of infectious diseases— including HIV, hepatitis C virus (HCV) and bacterial infections, and sexually transmitted infections— but workforce shortages, stigma, and administrative burdens are preventing the integration of opioid use disorder (OUD) and infectious disease services, says a new report from the National Academies of Sciences, Engineering, and Medicine. It recommends a number of state and federal policy actions to address those barriers, including removing insurance requirements on prescribing medications for OUD (i.e., buprenorphine), ...
Source: News from the National Academies - Category: Science Source Type: news
AbstractHuman pegivirus 2 (HPgV-2) is a recently recognized pegivirus of the familyFlaviviridae. To investigate the epidemic features of HPgV-2 circulating in the human immunodeficiency virus (HIV)-infected population, we tested for antibodies and viral RNA of HPgV-2 and hepatitis C virus (HCV) with retrospective plasma samples collected from 771 HIV infections with multiple risk behaviors in Honghe Prefecture of Yunnan Province. A total of 195 subjects (25.29%) were seroreactive to HPgV-2, and 41 (5.32%) were RNA positive. Although the positive rate of HPgV-2 antibodies in HIV/HCV-coinfected individuals (27.69%) was signi...
Source: Archives of Virology - Category: Virology Source Type: research
AbstractPurpose of ReviewThe prevalence of Hepatitis C virus (HCV) in the US incarcerated population is disproportionately high, and when inmates with infection are released back into the general population, they play a substantial role in the spread of disease. This review provides support for targeting the jail/prison population to eliminate HCV in the general population. It will also summarize various screening/treatment models to curtail the burden of disease behind and beyond bars.Recent FindingsTransitioning from risk-based testing to opt-out testing in prisons/jails would be cost-effective through greater identifica...
Source: Current HIV/AIDS Reports - Category: Infectious Diseases Source Type: research
Hepatitis C virus (HCV) is one of the most significant public health problems currently facing the United States, especially in West Virginia. If it is undetected and left untreated, the likelihood of sustaining a treatment response decreases. While early identification has been identified as a critical focus in trying to obtain better health outcomes, new drug treatments appear promising, if somewhat expensive. West Virginia is a predominantly rural state, where the incidence of HCV is 9 times the national average and Medicaid costs for treatment amounted to more than $27 million from 2014 to 2016. The purpose of this stu...
Source: The Health Care Manager - Category: Health Management Tags: Article Source Type: research
The United States is in the midst of perinatal hepatitis C viral infection (HCV) and substance use syndemic, defined as two or more concurrent epidemics clustered in a population with biological interactions. Both perinatal substance use and HCV are associated with adverse maternal and neonatal outcomes. However, whether HCV is an independent risk factor for adverse outcomes remains unknown. Our objective was to assess the risk of adverse maternal and neonatal outcomes attributable to HCV.
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Poster Session V Source Type: research
Publication date: Available online 18 December 2019Source: The Lancet Global HealthAuthor(s): Josephine G Walker, Tinatin Kuchuloria, David Sergeenko, Hannah Fraser, Aaron G Lim, Shaun Shadaker, Liesl Hagan, Amiran Gamkrelidze, Valeri Kvaratskhelia, Lia Gvinjilia, Malvina Aladashvili, Alexander Asatiani, Davit Baliashvili, Maia Butsashvili, Ivdity Chikovani, Irma Khonelidze, Irma Kirtadze, Mark H Kuniholm, David Otiashvili, Lali SharvadzeSummaryBackgroundGeorgia has a high prevalence of hepatitis C, with 5·4% of adults chronically infected. On April 28, 2015, Georgia launched a national programme to eliminate hepati...
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
This study summarizes the literature evaluating the impact of CPs in the management of PLWH in the era of modern ART. We conducted a literature search to identify studies that assessed the CP role in HIV clinical practice since 2006. The identified studies were grouped into two categories. The first was HIV related outcomes, including interventions on regimen selection, adherence, regimen optimization, and management of treatment failure. The second group of studies pertained to aging and vulnerable populations, including management of comorbidities, transitions of care, medication-assisted treatment, hepatitis C, and HIV ...
Source: AIDS Reviews - Category: Infectious Diseases Authors: Tags: AIDS Rev Source Type: research
ConclusionsClinical testing guidelines have not been effectively translated to practice. Additionally, compared to HIV and HBV, HCV infections during pregnancy are becoming more prevalent, yet current national HCV screening guidelines are the least comprehensive.
Source: Maternal and Child Health Journal - Category: Health Management Source Type: research
Publication date: Available online 11 December 2019Source: EpidemicsAuthor(s): Theresa Stocks, Leah J. Martin, Sharon Kühlmann-Berenzon, Tom BrittonAbstractTo reach the WHO goal of hepatitis C elimination, it is essential to identify the number of people unaware of their hepatitis C virus (HCV) infection and to investigate the effect of interventions on the disease transmission dynamics. In many high-income countries, one of the primary routes of HCV transmission is via contaminated needles shared by people who inject drugs (PWIDs). However, substantial underreporting combined with high uncertainty regarding the size ...
Source: Epidemics - Category: Epidemiology Source Type: research
Conclusions: As seemingly benign viruses could turn deadly (e.g., Zika flavivirus) and EqHV happens to have infected a significant proportion of the world’s horse herds, EqHV infectious cycle should be further clarified.
Source: Viruses - Category: Virology Authors: Tags: Communication Source Type: research
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