Expression of growth arrest-specific protein 6 and Axl molecules in the left internal mammary artery of patients undergoing coronary artery bypass grafting

Conclusions The present study discovered that the higher expression of Gas6/Axl pathway components in the LIMA compared with that in the aorta may partly explain the less frequent atherosclerotic events involving the LIMA compared with other arteries. Moreover, Gas6 may play a critical and protective role in human vascular biology.
Source: Journal of Clinical Pathology - Category: Pathology Authors: Tags: Immunology (including allergy) Original article Source Type: research

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Publication date: March 2019Source: The Annals of Thoracic Surgery, Volume 107, Issue 3Author(s): Ewa M. Zywicka, Thomas Theologou, Susannah Love, Omar NawaytouNickel hypersensitivity has been reported in up to 15% of the general population, and cases of nickel allergy have been correlated with use of stainless steel wires. This is a case report of a 48-year-old woman with history of contact allergy to metal who underwent elective coronary artery bypass grafting. Severe systemic inflammatory response and cardiac tamponade due to edema of mediastinal tissues developed postoperatively. The patient required removal of stainle...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
CONCLUSION Earlier reports of increased pain sensitivity 1 year after the use of remifentanil could not be confirmed in this randomised study using Quantitative Sensory Testing. This indicates that remifentanil plays a minor role in the development of chronic thoracic pain. Still, the relatively high incidence of chronic thoracic pain and its accompanying impact on quality of life remain challenging problems. TRIAL REGISTRATION The study was registered at EudraCT (ref: 2013-000201-23) and ClinicalTrials.gov (https://clinicaltrials.gov/ct2/show/NCT02031016).
Source: European Journal of Anaesthesiology - Category: Anesthesiology Tags: Postoperative pain Source Type: research
Abstract Metal allergy is an uncommon problem during surgery. Among them, titanium allergy is said to be rare, but can lead to serious complications, such as palmoplantar pustulosis (PPP). A 69-year-old woman was admitted to our hospital with a chief complaint of chest pain. Coronary angiography showed severe coronary artery disease that required coronary artery bypass grafting (CABG). The patient had a history of orthopedic surgery for left distal radius fracture 2 years previously, which resulted in inflammation on the left arm and PPP. We suspected titanium allergy based on results of skin patch tests and use o...
Source: Annals of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Ann Thorac Cardiovasc Surg Source Type: research
Publication date: Available online 1 November 2017 Source:The Lancet Author(s): Olivier Varenne, Stéphane Cook, Georgios Sideris, Sasko Kedev, Thomas Cuisset, Didier Carrié, Thomas Hovasse, Philippe Garot, Rami El Mahmoud, Christian Spaulding, Gérard Helft, José F Diaz Fernandez, Salvatore Brugaletta, Eduardo Pinar-Bermudez, Josepa Mauri Ferre, Philippe Commeau, Emmanuel Teiger, Kris Bogaerts, Manel Sabate, Marie-Claude Morice, Peter R Sinnaeve Background Elderly patients regularly receive bare-metal stents (BMS) instead of drug-eluting stents (DES) to shorten the duration of double antiplatele...
Source: The Lancet - Category: General Medicine Source Type: research
Dutch suturing tech company Mellon Medical said today that it has raised €6 million (equivalent to about $6.6 million) to advance its Switch instrument. Mellon Medical officials boast that their Switch single use precision-suturing instrument enables surgeons to suture tubular and layered structures about twice as fast as conventional methods. Reduced clamp time for many cardiovascular procedures equals reduced complications risk, better patient outcomes and reduced costs, according to the company. “By collaborating with medical specialists, industrial designers and ergonomic experts in the development...
Source: Mass Device - Category: Medical Devices Authors: Tags: Business/Financial News News Well mellonmedical surgery Source Type: news
This case comes from Max Nelson, a paramedic in Australia.See also this post:40-something with severe CP. True + vs. False + high lateral MI. ST depression does not localize.CaseI was dispatched to a middle age woman (~50YO) with chest pain and nausea.Exam: pt is huddled around toilet bowel, naked and shivering. Pt appears “well” but with pallor.Hx: pt was woken from sleep after midnight with chest aching, dyspnoea and significant nausea. Pt moved to the toilet and had one bilious vomit. The ambulance was called and arrived approx 20 minutes later.Signs and symptoms: nausea, dyspneoa, cold, pallor.Now states ch...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
​BY AARON SNYDER, MDInfectious processes, such as streptococcal infections, can partially masquerade as alternative diagnosis. Streptococcal infections are a frequent source of infection treated by emergency physicians, and it is crucial that the appropriate tests, antibiotics, and hospitalization are used to recognize rash patterns and to identify causes and the differential of causation.A 60-year-old woman presented from her primary medical doctor's office with fever, fatigue, tachycardia, and facial discomfort for two days that developed into a malar rash. The patient reported one day of fever, several days of sore th...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
Publication date: Available online 9 September 2016 Source:Journal of Cardiology Cases Author(s): Masao Imai, Atsuo Fukuda, Nobuhide Miyamoto, Hidenori Sako, Takeshi Kimura, Katsumi Inoue A 68-year-old female underwent bare-metal stent (BMS) implantation in the right coronary artery (RCA) for ST-segment elevation myocardial infarction. Recurrent refractory restenosis with peri-stent contrast staining (PSS) formation was observed in the stented lesion at follow-up angiography at 7, 11, and 14 months after the index stent implantation. After 2 repeated interventions, this patient was referred to coronary artery bypass graft...
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research
Abstract Heparin resistance (unresponsiveness to heparin) is characterized by the inability to reach acceptable activated clotting time values following a calculated dose of heparin. Up to 20% of the patients undergoing cardiothoracic surgery with cardiopulmonary bypass using unfractionated heparin (UFH) for anticoagulation experience heparin resistance. Although UFH has been the "gold standard" for anticoagulation, it is not without its limitations. It is contraindicated in patients with confirmed heparin-induced thrombocytopenia (HIT) and heparin or protamine allergy. The safety and efficacy of the use...
Source: Perfusion - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Perfusion Source Type: research
In conclusion, we show that minimally invasive coronary surgery might feasibly be done without the aid of metal implants or surgical clips for hemostasis.
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
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