Link between herpes in pregnancy and autism is unconfirmed

Conclusion This was a Norwegian case-control study that looked at whether maternal infections during pregnancy are associated with the risk of neurological developmental disorders such as autism spectrum disorders (ASDs) in their children. The study initially found no association between any of the pathogens during pregnancy or after delivery, and the development of ASD in boys or girls. Further investigations suggested that high levels of HSV-2 virus antibodies during mid-pregnancy were associated with increased risk of the development of ASD in boys. The researchers suggest that the suspected risk of ASD associated with high levels of virus is not down to the HSV-2 virus itself but the impact of inflammation and the subsequent activation of the immune system on child development during pregnancy However, while this finding has been widely reported in the media, it is based on just 14 women so is not reliable. Performing repeated unplanned analyses is bound to come up with some association in the end through sheer chance. It is important that pregnant women do take precautions to prevent herpes infection during pregnancy, especially the third trimester, as there is a risk of passing the virus on to the baby. More research would be needed to confirm the speculations that herpes infection during pregnancy can increase the risk of autistic spectrum disorder.   Links To The Headlines Pregnant women infected with herpes are ‘TWICE as likely to have a baby with ...
Source: NHS News Feed - Category: Consumer Health News Tags: Pregnancy/child Neurology Mental health Source Type: news

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2019 has become the year when antiabortion politicians make clear that their ultimate agenda is banning abortion outright, at any stage in pregnancy and for any reason.
Source: The Guttmacher Institute - Category: International Medicine & Public Health Authors: Source Type: news
Reported cases of mumps and pertussis have risen in the US in recent years even though many people are vaccinated. As part of the FDA commitment to protect the public health, FDA scientists are working to learn why more cases are occurring.
Source: FDA Consumer Health Information Updates - Category: Consumer Health News Authors: Source Type: news
This study compares the effects of rFSH only, rLH + rFSH, and HMG + rFSH administration on in vitro fertilization (IVF) outcomes for patients in three different yearly follow-up cycles. Material and methods: This retrospective, single-center cohort study was conducted from January 2001 to June 2016 at Istanbul Memorial Hospital, Artificial Reproductive Technology Center. From a total of 27,024 IVF cycles in women aged 18 to 45 years (17,536 rFSH only; 2147 rLH + rFSH; 7341 HMG + rFSH), the results of 2,147 cycles receiving a treatment of rLH + rFSH over the 3-year evaluation and 2,081 total cycles in which rLH + rFSH w...
Source: Archives of Medical Science - Category: General Medicine Tags: Arch Med Sci Source Type: research
Conclusions: The IVF singleton pregnancies have an increased risk of adverse perinatal outcome, among which prematurity remains the greatest problem. Therefore, they should be managed as high risk not only due to psychological reasons. PMID: 31110532 [PubMed]
Source: Archives of Medical Science - Category: General Medicine Tags: Arch Med Sci Source Type: research
Conclusions: Our results revealed that PCSK9 inhibition may moderately improve breast cancer outcomes while having no harmful effects in tumor-bearing mice. PMID: 31110521 [PubMed]
Source: Archives of Medical Science - Category: General Medicine Tags: Arch Med Sci Source Type: research
Authors: Momtazi-Borojeni AA, Nik ME, Jaafari MR, Banach M, Sahebkar A Abstract Introduction: Inhibition of proprotein convertase subtilisin/kexin 9 (PCSK9) is an effective therapeutic tool for lowering low-density lipoprotein cholesterol (LDL-C). There is no available evidence on the efficacy and safety of PCSK9 inhibitors in non-cardiovascular diseases, particularly cancer. The present study aimed to evaluate the effect of PCSK9 inhibition on cancer endpoints in mice bearing colon carcinoma, using a nanoliposomal antiPCSK9 vaccine. Material and methods: The prepared nanoliposomal antiPCSK9 vaccine was subcuta...
Source: Archives of Medical Science - Category: General Medicine Tags: Arch Med Sci Source Type: research
A lot of IVF clinics take pride in the large number of cycles which they do . Their focus is on their turnover, because they are profit making corporates, who need to maximise their ROI for their investors.While is great for the management because this maximizes their revenue, it may not be good for each individual patient they treat. They use an assembly line approach, where every patient is treated as a widget, and the focus is on maximising throughput by using a "one-size-fits-all" approach.Our focus as a boutique clinic is very different ! We make sure that we spend a lot of time and energy on each individual...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
Authors: Shiha GE, El-Etreby S, Bahgat M, Hamed M, Sherbini ME, Ghoneem EA, Zalata K, Soliman RE, ElBasiouny MA, Mikhail NN Abstract INTRODUCTION AND AIM: Transient elastography is gaining popularity as a non-invasive method for predicting liver fibrosis, but inter observer agreement and factors influencing reproducibility have not been adequately assessed. MATERIAL AND METHODS: This cross-sectional study was conducted at Specialized Medical Hospital and the Egyptian Liver Foundation, Mansoura, Egypt. The inclusion criteria were: age older than 18 years and chronic infection by hepatitis C. The exclusion criter...
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
ConclusionsWe demonstrate that of the myelin specific promoters evaluated, P0 is optimal for driving expression of transgenes in schwannoma cells.
Source: Journal of Neuroscience Methods - Category: Neuroscience Source Type: research
Several lines of evidence support the hypothesis that abnormally elevated brain levels of kynurenic acid (KYNA), a metabolite of the kynurenine pathway (KP) of tryptophan degradation, play a pathophysiologically significant role in schizophrenia and other major neurodevelopmental disorders. Studies in experimental animal models suggest that KP impairments in these diseases may originate already in utero since prenatal administration of KYNA ’s bioprecursor, kynurenine, leads to biochemical and structural abnormalities as well as distinct cognitive impairments in adulthood. As KP metabolism during pregnancy is still i...
Source: Developmental Neuroscience - Category: Neuroscience Source Type: research
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