Prognostic Value of Serum 25-Hydroxyvitamin D in Patients with Stroke.

Prognostic Value of Serum 25-Hydroxyvitamin D in Patients with Stroke. Neurochem Res. 2014 May 1; Authors: Wang Y, Ji H, Tong Y, Zhang ZB Abstract We aimed to evaluate the association between 25-hydroxyvitamin D [25(OH) D] levels and both clinical severity at admission and outcome at discharge in patients with acute ischemic stroke (AIS). From June 2012 to October 2013, consecutive first-ever AIS patients admitted to the Department of Emergency of The Fourth Affiliated Hospital of Harbin Medical University, China were identified. Clinical information was collected. Serum 25(OH) D levels were measured at baseline. Stroke severity was assessed at admission using the National Institutes of Health Stroke Scale (NIHSS) score. Functional outcome was evaluated at discharge using the modified Rankin scale (m-Rankin). Multivariate analyses were performed using logistic regression models. During the study period, 326 patients were diagnosed as AIS and were included in the analysis. Serum 25(OH) D levels reduced with increasing severity of stroke as defined by the NIHSS score. There was a negative correlation between levels of 25(OH) D and the NIHSS (r = - 0.389, P = 0.000). In multivariate analyses, serum 25(OH) D level was an independent prognostic marker of discharge favorable functional outcome and survival [odds ratio 3.96 (2.85-7.87) and 3.36 (2.12-7.08), respectively, P = 0.000 for both, adjusted for NHISS, other predictors...
Source: Neurochemical Research - Category: Neuroscience Authors: Tags: Neurochem Res Source Type: research

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Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research
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Source: Indian Heart Journal - Category: Cardiology Source Type: research
Authors: Jang MU, Kang J, Kim BJ, Hong JH, Yeo MJ, Han MK, Lee BC, Yu KH, Oh MS, Choi KC, Lee SH, Hong KS, Cho YJ, Park JM, Cha JK, Kim DH, Park TH, Lee KB, Lee SJ, Lee J, Kim JT, Kim DE, Choi JC, Lee J, Lee JS, Gorelick PB, Bae HJ Abstract BACKGROUND: Using data from a large national stroke registry, we aimed to investigate the incidence and determinants of in-hospital and post-discharge recovery after acute ischemic stroke and the independence of their occurrence. METHODS: In-hospital recovery was defined as an improvement of 4 points or> 40% in the National Institutes of Health Stroke Scale (NIHSS) score ...
Source: Journal of Korean Medical Science - Category: Biomedical Science Tags: J Korean Med Sci Source Type: research
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Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Letter Section Source Type: research
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Source: Journal of Advanced Research - Category: Research Source Type: research
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Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - Category: Nutrition Authors: Source Type: research
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Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Source Type: research
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Source: Annals of Emergency Medicine - Category: Emergency Medicine Source Type: research
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Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Myocardial Infarction;   Stroke (Including Ischaemic Stroke and Transient Ischaemic Attack);   Unstable Angina;   Angina;   Ischaemic Heart Disease Intervention:   Drug: Acetylsalicylic Acid (Aspirin, BAYE4465) Sponsor:   Bayer Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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