Zimbabwe: Malaria Still a Big Killer

[The Herald]Monica Cheru -A week before he could complete the first term of his grade two at Hurumutumbu Primary School in Mutoko this year, Panashe Chaza died after a short illness. "At first we thought it was just a headache. Then three days later he took a turn for the worse. I hired a kombi which charged us US$10 to take my son to Huyuyu Clinic (about 12 Kilometres away). When we got there we woke up the nurse who tested his blood and said it was malaria. She gave him an injection and said that we needed to take him to Mutoko H
Source: AllAfrica News: Malaria - Category: Infectious Diseases Source Type: news

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ConclusionsAP appeared to show similar efficacy and safety, with a simpler mode of administration and easier compliance when compared with other ACTs used in the treatment of uncomplicated malaria. Considering that the potential evolution of drug resistance is of a great concern, additional RCTs with high-quality and more rigorous design are warranted to substantiate the efficacy and safety in different populations and epidemiological regions.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
The cleverest of enemies thrive on surprise attacks. Viruses—and coronaviruses in particular—know this well. Remaining hidden in animal hosts for decades, they mutate steadily, sometimes serendipitously morphing into more effective and efficient infectious agents. When a strain with just the right combination of genetic codes that spell trouble for people makes the leap from animal to human, the ambush begins. Such was the case with SARS-CoV-2, the coronavirus behind COVID-19, and the attack was mostly silent and insidious at first. Many people infected with SARS-CoV-2 remained oblivious as they served as the v...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Magazine Source Type: news
by Rebecca E. Watts, Anand Odedra, Louise Marquart, Lachlan Webb, Azrin N. Abd-Rahman, Laura Cascales, Stephan Chalon, Maria Rebelo, Zuleima Pava, Katharine A. Collins, Cielo Pasay, Nanhua Chen, Christopher L. Peatey, J örg J. Möhrle, James S. McCarthy BackgroundArtemisinin resistance is threatening malaria control. We aimed to develop and test a human model of artemisinin-resistant (ART-R)Plasmodium falciparum to evaluate the efficacy of drugs against ART-R malaria. Methods and findingsWe conducted 2 sequential phase 1, single-centre, open-label clinical trials at Q-Pharm, Brisbane, Australia, using the induced ...
Source: PLoS Medicine - Category: Internal Medicine Authors: Source Type: research
Anopheles mosquito, a vector of Malaria   In one half of the world, the mosquito is seen to most as a minor annoyance, but for others, mosquitoes are synonymous with disease, pain, and death. Today is the World Mosquito Day and the perfect reminder of the devastating impact of such diseases as Malaria, Zika, and various kinds of Encephalitis for which mosquitoes are a major vector. Malaria – a headline disease Malaria is the headline disease associated with mosquitoes and it was on this very day in 1897 that Sir Ronald Ross discovered that female mosquitoes can transmit malaria between h...
Source: GIDEON blog - Category: Databases & Libraries Authors: Tags: Epidemiology News Source Type: blogs
Authors: Singh MM, Meena RL, Garg RK, Prajapati MM, Samar N, Trivedi C, Sharma M, Shristi S, Mittal A Abstract A 70-year old female presented with complaints of fever with chills, headache for 15 days and altered sensorium for 7 days. Peripheral blood smear showed ring form of P. falciparum and CT brain revealed bilateral subdural hematoma. Patient received Artesunate based combination therapy and recovered completely without surgical intervention within 8 days of admission. PMID: 32610853 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
CONCLUSION: Thes studies will help in expanding the current therapeutic potential of C. sativa and it also provide a strong support to its future clinical use as herbal medicines having safe in use with no side effects. PMID: 32600228 [PubMed - as supplied by publisher]
Source: Mini Reviews in Medicinal Chemistry - Category: Chemistry Authors: Tags: Mini Rev Med Chem Source Type: research
Mosquito bites may be a nuisance, but fortunately, in the U.S., they tend to amount to nothing more than that. Upon being bitten, most Americans experience a bit of swelling and itchiness, and nothing more. However, there are exceptions to this, including stronger allergic reactions to bites and cases of mosquito-borne illness.  Insect and arachnid bites, including ticks, account for approximately 2,000 cases of malaria and 30,000 cases of Lyme disease in the U.S. annually. In addition, millions of people worldwide die of malaria each year. It is helpful to protect yourself against insect bites, not only to avoid pesk...
Source: Conversations with Dr Greene - Category: Child Development Authors: Tags: Dr. Greene's Blog Environmental Health Insect Bites & Stings Insects & Animals Outdoor Safety Source Type: blogs
NEW BRUNSWICK, NJ, May 27, 2020 — The Janssen Pharmaceutical Companies of Johnson &Johnson today announced that the U.S. Food and Drug Administration (FDA) has granted approval for a new pediatric formulation of SIRTURO® (bedaquiline). SIRTURO® is now indicated for use as part of combination therapy in the treatment of adult and pediatric patients (5 years and older and weighing at least 15 kg) with pulmonary multidrug-resistant tuberculosis (MDR‑TB). In the U.S., the medicine should be reserved for use when an effective treatment regimen cannot otherwise be provided. This indication received accelera...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
On April 20, the president calls a press conference to announce a breakthrough in the fight against COVID-19. It’s a new use for an old malaria treatment, he says, one that is seeing miraculous results among the country’s most ill patients. It’s so safe that even schoolchildren could take it. In fact, he urges them to do so daily, as a preventative. He admits that he, too, is taking the medicine. No, this is not the President of the United States touting an unproven remedy for a virus that has infected nearly 5 million people worldwide. It is Madagascar’s President Andry Rajoelina, who is just as wi...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 overnight Source Type: news
In case you were ever stupid enough to follow Trump’s lead you would have already injected ultraviolets in your eyeballs by now to save you from Covid and maybe bathed in Domestos or sulfuric acid or both! Anyway, his latest bullshine claim is that he’s been taking the antimalarial drug hydroxychloroquine to keep Covid at bay. Well, for starters there is no evidence that this drug acts as a prophylactic against infection with SARS CoV-2 or indeed any pathogen other than the causative agent of otherwise drug-resistant malaria. It’s primary use is in treating lupus. There was some testing done weeks ago to...
Source: David Bradley Sciencebase - Songs, Snaps, Science - Category: Science Authors: Tags: Health and Medicine Source Type: blogs
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