BP and Complications in Persons With T2DM and No Prior CVD BP and Complications in Persons With T2DM and No Prior CVD

How does a systolic blood pressure lower than the currently recommended 140 mm Hg impact CVD risk in patients who have type 2 diabetes and no previous CVD?British Medical Journal
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Internal Medicine Journal Article Source Type: news

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CONCLUSION: MS is beneficial where the main aim is to attain a significant and long-lasting weight loss results. The RCTs have depicted the superiority which surgical mechanisms hold over medically based therapy, for enhancing glycaemic control, and achieving remission of diabetes. This type of surgery improves life quality, reduces incidences of other obesity and diabetes relating diseases like microvascular illness, sleep apnea, fatal disorder, and fatty liver disease. PMID: 32077829 [PubMed - as supplied by publisher]
Source: Current Cardiology Reviews - Category: Cardiology Tags: Curr Cardiol Rev Source Type: research
Condition:   Type 2 Diabetes Intervention:   Dietary Supplement: BKR-017 Sponsor:   BioKier Inc. Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 20 February 2020Source: Trends in Endocrinology &MetabolismAuthor(s): Carsten Schmitz-PeifferThe failure of insulin to suppress glucose production by the liver is a key aspect of the insulin resistance seen in type 2 diabetes. Lipid-activated protein kinase C epsilon has long been identified as an important mediator of diet-induced glucose intolerance and hepatic insulin resistance and the current view emphasizes a mechanism involving phosphorylation of the insulin receptor by the kinase to inhibit downstream insulin action. However, the significance of this direct effect in the liver...
Source: Trends in Endocrinology and Metabolism - Category: Endocrinology Source Type: research
FRIDAY, Feb. 21, 2020 -- A higher proportion of older and multimorbid patients with type 2 diabetes achieve low hemoglobin A1c (HbA1c) levels, according to a study published online Feb. 19 in BMJ Open Diabetes Research&Care. Rozalina G. McCoy,...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
(Natural News) Adipokines are cell signaling proteins produced by adipose tissue (fat). These “circulating hormones” facilitate communication between various organs, such as the brain, liver and muscles. Dysregulation of adipokines, which also mediate inflammation, has dire consequences and is associated with serious health problems like obesity, cardiovascular disease and Type 2 diabetes. In a recent study, researchers from the Medical...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Authors: Koch TR, Shope TR Abstract Obesity is a major factor in the worldwide rise in the prevalence of type 2 diabetes mellitus. The obesity "epidemic" will require novel, effective interventions to permit both the prevention and treatment of diabetes caused by obesity. Laparoscopic vertical sleeve gastrectomy is a newer bariatric surgical procedure with a lower risk of complications (compared to Roux-en-Y gastric bypass surgery). Based in part on restriction of daily caloric intake, sleeve gastrectomy has a major role in inducing significant weight loss and weight loss is maintained for at least 10&nbs...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Contributors : Shubham Khetan ; Michael L StitzelSeries Type : OtherOrganism : Mus musculus ; synthetic constructWe tested>13,000 sequences containing each allele of 6,628 SNPs associated with altered in vivo chromatin accessibility in human islets and/or type 2 diabetes risk (T2D GWAS SNPs) for transcriptional activity in ß cell under steady state and endoplasmic reticulum (ER) stress conditions using the massively parallel reporter assay (MPRA).
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Other Mus musculus synthetic construct Source Type: research
Publication date: Available online 20 February 2020Source: IDCasesAuthor(s): Heather L. Clark, Hugo E. Valencia, Jennifer J. Findeis-Hosey, Steve N. GeorasAbstractAspergillus molds are ubiquitous environmental molds that can cause devastating invasive infections in immunocompromised patients. These infections often go unrecognized in critically ill patients. This case describes a 68 year-old female resident of a long-term nursing facility with history of dementia, nonalcoholic fatty liver disease with cirrhosis, chronic kidney disease stage III and insulin-dependent type 2 diabetes who presented with vomiting, diarrhea and...
Source: IDCases - Category: Infectious Diseases Source Type: research
In this long ‐term follow‐up of women with GDM, we found that 2‐hour glucose during OGTT at pregnancy predicted β‐cell function (as measured by ODI) 22 years post‐partum. Results of 2‐hour glucose during OGTT at pregnancy is a more useful indicator of long‐term metabolic risk. Most of the cases wh ich later converted to type 2 diabetes occurred within the first 15 years postpartum. AbstractAims/IntroductionWomen with gestational diabetes mellitus are at increased risk for type  2 diabetes. We characterized the association between maternal glycemia during pregnancy with long‐term outcomes.Methods a...
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: Original Article Source Type: research
AbstractObesity and insulin resistance are at the centre of most cases of metabolic syndrome (MetS), which may increase the risk of cardiovascular disease approximately 2 ‐fold and type 2 diabetes mellitus approximately 5‐fold. Aside from lifestyle intervention and drug therapy, bariatric surgery (BS) is considered a definitive treatment for this disease.
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: JDI UPDATES Source Type: research
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