#390 : the fort worth aya oncology coalition

The Fort Worth Adolescent and Young Adult Oncology Coalition recently opened the first community-supported AYA oncology inpatient unit in the nation. Dr. Karen Albritton (Medical Director) and Justin Ozuna (Director of Communications and Community Engagement) join us to discuss this game-changing unit and unique young adult-related services provided. Survivor Spotlight on young adult Hodgkin's Lymphoma survivor Erica Campbell.  
Source: The Stupid Cancer Show - Blog Talk Radio - Category: Cancer & Oncology Authors: Tags: Health Source Type: podcasts

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Radiotherapy is frequently used in the therapy of lymphoma. Since lymphoma, for example Hodgkin ’s disease, frequently affect rather young patients, the induction of secondary cancer or other long-term adverse ...
Source: Radiation Oncology - Category: Cancer & Oncology Authors: Tags: Research Source Type: research
Hydroa vacciniforme-like lymphoproliferative disorder (HVLPD) is a rare Epstein-Barr virus (EBV) associated T-cell lymphoproliferative disease. The term HVLPD has been renamed from hydroa vacciniforme-like lymphoma to lymphoproliferative disorder according to 2016 WHO classification due to its relationship with chronic active EBV infection and a spectrum in terms of its clinical course. It usually affects children and young adolescents, although adult and elderly cases have been reported. Clinically, it is characterized by recurrent erythematous papules and vesicles leaving pitted scars on the sun-exposed area including face and forearms.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Melanoma and Other Skin Cancers Source Type: research
ConclusionThe use of a pediatric-inspired protocol for high-risk AYA ALL patients was effective and well tolerated with improvement in OS and DFS compared with historical data using adult protocols in such populations.
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research
Treatment of B-cell acute lymphoblastic leukemia (ALL) and lymphoma using chimeric antigen receptors (CARs) targeting B-cell surface protein CD19 has demonstrated impressive clinical results in children and young adults. Despite the promising results from CD19 CAR therapy, up to 40% of patients, who initially achieve remission, eventually relapse. Relapse or non-response to CD19-directed CAR therapy may be due to low or diminished CD19 expression. Such patients would be predicted to benefit from CAR therapies targeting other B-cell surface proteins, such as CD22.Scientists at the National Cancer Institute ’s (NCI) Pe...
Source: NIH OTT Licensing Opportunities - Category: Research Authors: Source Type: research
AbstractOver 70,000 US young adults are diagnosed with cancer annually, disrupting important life transitions and goal pursuits. Hope is a positive psychology construct associated with better quality of life (QOL) that focuses on goal-oriented thinking. We developed and tested Achieving Wellness After Kancer in Early life (AWAKE), a scalable 8-week app-based program consisting of educational videos, mood/activity tracking, and telephone-based coaching to promote hope and QOL in young adult cancer survivors (YACS, 18 –40 years old). A two-arm RCT was used to examine the feasibility, acceptability, and potential e...
Source: Journal of Cancer Education - Category: Cancer & Oncology Source Type: research
SummaryOsteosarcoma (OS) is the most common primary malignant bone tumor and mainly affects children and adolescents. The OS five-year survival rate remains very low. Thus, novel therapeutic protocols for the treatment of OS are needed. Several approaches targeting deregulated signaling pathways have been proposed. The antitumoral effects of polyphenols, which are naturally occurring compounds with potent antioxidant and anti-inflammatory activity, have been investigated in different tumors. Gossypol, which is a natural polyphenolic aldehyde isolated from the seeds of the cotton plant, has been shown to exert antitumoral a...
Source: Investigational New Drugs - Category: Drugs & Pharmacology Source Type: research
ConclusionsAYA in the US experience disparities in cancer survival based on insurance status, independent of late stage of presentation. Patients age 26 ‐39 may be especially vulnerable to health outcomes associated with poor socioeconomic status, treatment disparities, and poor access to care.
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
Conclusions: Lung cancer in young adults is distinctive, with adenocarcinoma and stage IV at presentation being predominant characteristics. Gene mutation assessment should be mandatory in this subgroup due to the increased likelihood of positive driver gene alterations, as individualized targeted therapy may achieve superior outcomes.
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
Publication date: Available online 25 May 2019Source: Leukemia Research ReportsAuthor(s): Aya Nakaya, Shinya Fujita, Atsushi Satake, Takahisa Nakanishi, Yoshiko Azuma, Yukie Tsubokura, Ryo Saito, Akiko Konishi, Masaaki Hotta, Hideaki Yoshimura, Kazuyoshi Ishii, Tomoki Ito, Shosaku Nomura
Source: Leukemia Research Reports - Category: Hematology Source Type: research
ConclusionThe use of pediatric-inspired protocol for high risk AYA ALL was effective and well tolerated with improvement in OS and DFS compared to historical data using adult protocols in such population
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research
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