Cindy J.

The success Cindy has seen with her migraines has been well-documented in others. There are some studies available on my site that highlight this. – Dr. Perlmutter I have suffered from migraines for 26 years. They have been debilitating and over the years I have tried everything to prevent them. My neurologist has prescribed an arsenal of drugs, including beta-blockers, anti-depressants, calcium channel blockers, antihistamines and topamax. I tried eliminating triggers from my diet to no avail. I always got a migraine when the pressure dropped and there was a storm. Nothing stopped my weekly headaches. Sometimes I had them several times a week. Four years ago I found a doctor that changed my way of thinking about my diet. My mother has Alzheimer’s and I want to do whatever I can to prevent it. My blood work started showing elevated blood sugar and I couldn’t figure out why. She coached me to eliminate gluten and to increase the right kind of protein in my diet. I was eating too many carbs. The migraines continued. In January, I happened to see Dr. Perlmutter being interviewed on TV. I bought Grain Brain and immediately realized what was wrong. I had substituted gluten-free carbs for regular carbs, but I was still eating too many carbs. I stopped the oatmeal and gluten free toast for breakfast, I started making omelets cooked in coconut oil with greens and avocado. I still have my shake with organic berries for lunch. I snack on nuts ...
Source: Renegade Neurologist - A Blog by David Perlmutter, MD, FACN - Category: Neurologists Authors: Tags: Success avocado carbs coconut oil gluten free Headaches Migraine protein Shake Source Type: blogs

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Abstract NLC is a next-generation lipid nanocarrier which holds many advantages over other colloidal lipid carrier system like higher drug loading, better and controlled release and enhanced stability. Owing to the unique structural composition, i.e. crystallized solid and liquid lipid blend it offers excellent biocompatibility and higher permeation across physiological membranes like BBB. Moreover, the surface of NLC can be easily modified with target-specific ligands, proteins, peptides, etc. which makes it a potential candidate for brain targeting of CNS acting drugs. NLC has found various applications in treat...
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Tags: Curr Pharm Des Source Type: research
ConclusionsThese findings suggest that EEDM significantly attenuates scopolamine-induced memory impairment in mice and may be a promising therapeutic agent for improving memory impairment.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
This study confers the discipline, frameworks, and methodologies used by different deep learning techniques to diagnose different human neurological disorders. Here, one hundred and thirty-six different articles related to neurological and neuropsychiatric disorders diagnosed using different deep learning techniques are studied. The morbidity and mortality rate of major neuropsychiatric and neurological disorders has also bee n delineated. The performance and publication trend of different deep learning techniques employed in the investigation of these diseases has been examined and analyzed. Different performance metrics ...
Source: Journal of Medical Systems - Category: Information Technology Source Type: research
Authors: Chayasirisobhon S Abstract Cannabis plant has the scientific name called Cannabis sativa L. Cannabis plant has many species, but there are three main species including Cannabis sativa, Cannabis indica and Cannabis ruderalis. Over 70 compounds isolated from cannabis species are called cannabinoids (CBN). Cannabinoids produce over 100 naturally occurring chemicals. The most abundant chemicals are delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD). THC is psychotropic chemical that makes people feel "high" while CBD is nonpsychotropic chemical. However, cannabinoid chemicals are not found only...
Source: Acta Neurologica Taiwanica - Category: Neurology Tags: Acta Neurol Taiwan Source Type: research
Abstract Treatment of neurological diseases using systemic and non-surgical techniques presents a significant challenge in medicine. This challenge is chiefly associated with the condensation and coherence of the brain tissue. The coherence structure of the brain is due to the presence of the blood brain barrier (BBB), which consists of a continuous layer of capillary endothelial cells. The BBB prevents most drugs from entering the brain tissue and is highly selective, permitting only metabolic substances and nutrients to pass through. Although this challenge has caused difficulties for the treatment of neurologic...
Source: Current Pharmaceutical Biotechnology - Category: Biotechnology Authors: Tags: Curr Pharm Biotechnol Source Type: research
CONCLUSIONS: In this review, biological and chemical knowledge of melatonin, its experimental effects, and the clinical impact on patients with neurological disorders were described. According to all of the beneficial results obtained from experimental and clinical trials, melatonin may have a prophylactic and therapeutic effect on neurological diseases. Strong collaboration between neurologists and health service policy makers is needed to encourage use of melatonin in the patients suffering from neurological diseases. Melatonin may be the solution we have been looking for. PMID: 31718830 [PubMed - as supplied by publisher]
Source: Revue Neurologique - Category: Neurology Tags: Rev Neurol (Paris) Source Type: research
CONCLUSIONS: Brexpiprazole 2 mg/day has the potential to be efficacious, safe, and well tolerated in the treatment of AAD. PMID: 31708380 [PubMed - as supplied by publisher]
Source: The American Journal of Geriatric Psychiatry - Category: Psychiatry Tags: Am J Geriatr Psychiatry Source Type: research
Abstract Purinergic signaling was proposed in 1972, after it was demonstrated that adenosine 5'-triphosphate (ATP) was a transmitter in nonadrenergic, noncholinergic inhibitory nerves supplying the guinea-pig taenia coli. Later, ATP was identified as an excitatory cotransmitter in sympathetic and parasympathetic nerves, and it is now apparent that ATP acts as a cotransmitter in most, if not all, nerves in both the peripheral nervous system and central nervous system (CNS). ATP acts as a short-term signaling molecule in neurotransmission, neuromodulation, and neurosecretion. It also has potent, long-term (trophic) ...
Source: Mol Biol Cell - Category: Molecular Biology Authors: Tags: Methods Mol Biol Source Type: research
However, no link seen between migraines and vascular dementia
Source: The Doctors Lounge - Psychiatry - Category: Psychiatry Tags: Neurology, Psychiatry, Geriatrics, Journal, Source Type: news
New research finds a 'significant' association between a history of migraine and various forms of dementia, and Alzheimer's disease in particular.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Neurology / Neuroscience Source Type: news
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