Weight gain reveals dramatic increases in skeletal muscle extracellular matrix remodeling.

Conclusion: We propose that skeletal muscle extracellular matrix remodeling is another feature of the pathogenic milieu associated with energy excess and obesity, which if disrupted may contribute to the development of metabolic dysfunction. PMID: 24601694 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research

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Conclusions These results suggest being older, previously injured, obese (body mass index ≥ 35 kg·m−2), and less active is associated with being less willing to participate in the PROPAT, whereas males and reporting a higher importance of the TASKRUN and TASKDRAG activities is associated with being more willing to participate in the PROPAT. Departments can use these findings to identify feasible strategies (e.g., education and physical training) to improve the implementation of physical employment standards.
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: APPLIED SCIENCES Source Type: research
ConclusionOur study suggests that regular exercise alters the equilibrium between oxidative and anti-oxidative compounds and reduces pro-inflammatory cytokines.
Source: European Journal of Nutrition - Category: Nutrition Source Type: research
ConclusionObesity, higher alcohol and heme iron consumption were the main risk factors for excess iron in males while only age was associated with iron overload in females. Weight control and promoting healthy lifestyle may help prevent iron overload, especially in obese people. Further research is needed to clarify determinants of excess iron in the healthy adult population, helping to reduce the associated comorbidities.
Source: European Journal of Nutrition - Category: Nutrition Source Type: research
This study was designed to examine the effects of alternate-day fasting (ADF) and 16/8 time-restricted fasting (16/8 TRF) on weight loss, blood glucose, and lipid profile in overweight and obese adults with prediabetes. Methods A randomized controlled trial was conducted on a sample of 101 overweight and obese adults with prediabetes. The participants were randomized into the ADF group (n = 34), 16/8 TRF group (n = 33), and control group (n = 34). The intervention lasted for 3 weeks. Data on body weight, body mass index, waist circumference, blood glucose, and lipid profile were collected at baseline, at the end of ...
Source: Journal of Nursing Research - Category: Nursing Tags: ORIGINAL ARTICLES Source Type: research
ConclusionOur study suggests that regular exercise alters the equilibrium between oxidative and anti-oxidative compounds and reduces pro-inflammatory cytokines.
Source: European Journal of Nutrition - Category: Nutrition Source Type: research
Once-a-week injection of this drug led overweight or obese people to lose more than a fifth of their weight.
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Weight Loss Source Type: blogs
AbstractPurposeThe purpose of this study is to evaluate the effectiveness and safety of liraglutide/liraglutide  + metformin in overweight/obese women with polycystic ovary syndrome (PCOS).MethodsThe related literatures published until April 2021 were searched in PubMed, Cochrane Library, MEDLINE and EmBase.ResultsSix randomized controlled trials of 127 related articles were obtained through searching. Three articles compared liraglutide with metformin, and four articles compared liraglutide combined with metformin with metformin. Our meta-analysis suggests that liraglutide was superior to metformin only in w...
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research
ConclusionsLog %50 was the metric for which the short-term variability was largely independent of a child's BMI. Changes in log %50th, %95th, and %50th are strongly correlated.
Source: Pediatric Obesity - Category: Eating Disorders & Weight Management Authors: Tags: ORIGINAL RESEARCH Source Type: research
Thank you, Dr. Kara Pepper, for your recent article “Why you should not use BMI for your New Year’s resolution.” Our weight-obsessed, BMI-focused culture has been a thorn in my side for much of my life. And since eating disorders thrive in secrecy, let’s get talking. In sharing my story, I hope to encourage revisionRead more …Eating disorders thrive in secrecy, so let ’s talk about it. Starting with BMI. originally appeared inKevinMD.com.
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions Obesity Source Type: blogs
We describe the effective management of a 57-year-old morbidly obese male who presented with acute airway obstruction and respiratory failure.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Case Report Source Type: research
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