Are Young Adult Women with Polycystic Ovary Syndrome Slipping through the Healthcare Cracks?

Are Young Adult Women with Polycystic Ovary Syndrome Slipping through the Healthcare Cracks? J Clin Endocrinol Metab. 2014 Feb 25;:jc20134190 Authors: Dokras A, Witchel SF Abstract Polycystic ovary syndrome is a common endocrine disorder often diagnosed in adolescence or early adulthood. In adolescence, the many similarities between normal features of puberty and symptoms of PCOS make it challenging to confirm the diagnosis. Even among adult women, the changing definitions of PCOS may lead to inaccurate diagnoses. Women may present with a variety of symptoms to different healthcare providers, and may be treated only for the presenting symptoms without evaluation of the syndrome and its associated morbidities. Timely evaluations, accurate diagnosis, appropriate interventions, and multidisciplinary healthcare teams can be valuable because women with PCOS have an increased risk for obesity, impaired glucose tolerance, diabetes, dyslipidemia, metabolic syndrome, infertility, endometrial cancer and anxiety and mood disorders. Appropriate transition of care for the adolescent from pediatric to adult health care providers should include education of the patient and her parents regarding the chronic nature of the syndrome and need for continued follow up. Girls with symptoms suggestive of PCOS who fail to fulfill diagnostic criteria should undergo prolonged observation. Early identification of PCOS at different entry points in the health care system will require phys...
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research

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The American Congress of Rehabilitation Medicine (ACRM) offers an opportunity for members to be the guest editor of a Supplement to its journal, the Archives of Physical Medicine and Rehabilitation (Archives). The goal of the ACRM supplements is to publish high quality scientific manuscripts, which are thematically organized and of interest to ACRM members and to the general readership of the Archives. We are interested in proposals in all fields of rehabilitation, but especially those of interest to the ACRM membership as indicated by the existence of special interest and networking groups for brain injury, spinal cord in...
Source: Archives of Physical Medicine and Rehabilitation - Category: Rehabilitation Tags: Organization news Source Type: research
Healthy women age 75 and older may not benefit from continued breast cancer...Read more on AuntMinnie.comRelated Reading: Is breast screening beneficial for sickly older women? ACP pushes breast cancer screening start from 40 to 50 DBT screening mammography benefits women over 65 Screening mammography still good for older women Age, not density, predicts interval breast cancer result
Source: Headlines - Category: Radiology Source Type: news
Targeting joint capsule abnormalities in the shoulder on MRI scans can help...Read more on AuntMinnie.comRelated Reading: Gadolinium MRI improves diagnosis of shoulder condition Musculoskeletal speakers reveal trade secrets on sports injuries 5-minute shoulder MRI could ease patient anxiety AIUM: Is MRI really needed after MSK ultrasound? Study: Skip the x-rays after shoulder arthroplasty surgery
Source: Headlines - Category: Radiology Source Type: news
Basel, 25 February 2020 – Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the US Food and Drug Administration (FDA) has accepted the company’s Biologics License Application (BLA) for the fixed-dose combination (FDC) of Perjeta® (pertuzumab) and Herceptin® (trastuzumab) with hyaluronidase, administered by subc utaneous (SC) injection in combination with intravenous (IV) chemotherapy, for the treatment of eligible patients with HER2-positive breast cancer. The BLA for the FDC is based on results from the phase III FeDeriCa study, which demonstrated non-inferior levels of Perjeta in the blood (phar...
Source: Roche Investor Update - Category: Pharmaceuticals Source Type: news
ConclusionsOur results suggest that the peroxisome proliferator ‐activated receptor gamma 2Ala12 variant has significant protective effects against albuminuria and DN.
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: Original Article Source Type: research
AbstractBackground/ObjectiveNon ‐alcoholic fatty liver disease (NAFLD) is more and more common in patients with type 2diabetes mellitus (T2DM). Currently, some researches have found that Sodium glucose co‐ transporter2 (SGLT2) inhibitors, a new hypoglycemic drug, can improve nonalcoholic fatty liver besides hypoglycemic effect . Thus, we undertook a meta‐analysis of randomized controlled trials (RCTs) to evaluate the efficacy of SGLT2 inhibitors on the treatment of NAFLDMethodsPubMed, Embase and the Cochrane Library were searched for RCTs of SGLT2 inhibitors in patients with NAFLD and T2DM up to Oct1, 2019. Differenc...
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: ORIGINAL ARTICLE Source Type: research
ConclusionMetabolic biomarkers were affected by blood sample timing and underlying metabolic disease. The JECS will clarify the influences of metabolic status during pregnancy on the health and development of the offspring in future studies.
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: ORIGINAL ARTICLE Source Type: research
We present the case of a 12 ‐year‐old Japanese girl, who was positive for markers of both maturity‐onset diabetes of the young and latent autoimmune diabetes in youth. She was initially diagnosed with maturity‐onset diabetes of the young 1 based on the molecular analysis, and she later developed an autoimmune response , leading to β‐cell‐associated antibody‐positive diabetes. She was treated with incretin‐associated drugs and maintained adequate glycemic control. Pathophysiologically, there was an overlap between the two different types of diabetes, because the hyperglycemia and β‐cell stre...
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: Case Report Source Type: research
DiabetesMine answers key questions on the connection between type 1 diabetes and cardiovascular risk.
Source: Diabetes Mine - Category: Endocrinology Authors: Source Type: blogs
ConclusionsThere is a rich traditional knowledge regarding the ethnomedicinal uses of Hypericum species in China. Through phytochemical and pharmacological studies, several medicinal Hypericum from China have yielded many bioactive phytochemicals, possessing antitumor, anti-inflammatory, antimicrobial, and neuroprotective properties. Hypericum species from China are potential sources of drugs to fight cancer and other chronic diseases. Remarkably, nearly half of Hypericum species in China have rarely been studied, and their ethnomedicinal potential have not been scientifically evaluated. Thus, in vitro mechanistic studies,...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
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