The mesolimbic system and eating addiction: what sugar does and does not do

Publication date: June 2016 Source:Current Opinion in Behavioral Sciences, Volume 9 Author(s): Johannes W De Jong, Louk JMJ Vanderschuren, Roger AH Adan Obesity and obesity-related disorders are a major threat to public health. It has been suggested that food addiction is a valid clinical concept and that food addiction is a contributing factor to the obesity epidemic. Research involving restricted access ‘binge’ diets has shown that rodents will display sucrose-related behavior that is reminiscent of substance addiction, under certain conditions. A question that remains, however, is if food or certain components of food possess addictive qualities akin to drugs of abuse. The alternative is that ‘food addiction’ (or rather ‘eating addiction’) is not a substance use disorder in the sense that people are addicted to any specific substance or component of food, but rather an addictive disorder involving disinhibition of food intake in general that shares similarities with behavioral addictions such as problem gambling. Here we describe how sugar (a candidate addictive component of frequently consumed foods) has short and long term effects on the brain and compare this to how addictive substances functionally alter the mesolimbic dopamine system. We focus on this system since plasticity changes in the mesolimbic system have been implicated in the development of drug addiction. We conclude that sugar has a strong direct influence on the dop...
Source: Current Opinion in Behavioral Sciences - Category: Psychiatry & Psychology Source Type: research

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Source: L Encephale - Category: Psychiatry Tags: Encephale Source Type: research
This article aims at proposing guidance to ensure mental health care during the SARS-CoV epidemy in France. METHODS: Authors performed a narrative review identifying relevant results in the scientific and medical literature and local initiatives in France. RESULTS: We identified four types of major vulnerabilities in patients suffering from mental disorders during this pandemic: (1) medical comorbidities that are more frequently found in patients suffering from mental disorders (cardiovascular and pulmonary pathologies, diabetes, obesity, etc.) which represent risk factors for severe infections with Covid-19; (2) a...
Source: L Encephale - Category: Psychiatry Tags: Encephale Source Type: research
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Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Editorial Comment Source Type: research
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Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
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Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Addiction Health Health care disparities Men's Health Women's Health Source Type: blogs
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Source: Clinical Nutrition - Category: Nutrition Authors: Tags: Original article Source Type: research
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Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
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Source: Acta Neuropsychiatrica - Category: Psychiatry Tags: Acta Neuropsychiatr Source Type: research
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Source: Journal of the American Osteopathic Association - Category: Complementary Medicine Tags: J Am Osteopath Assoc Source Type: research
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