Debate Arises Over HHS Plans for Privacy Rules on Addiction Treatment
(MedPage Today) -- Some feel proposed rules don't go far enough
AbstractGlutamine metabolism is one of the hallmarks of cancers which is described as an essential role in serving as a major energy and building blocks supply to cell proliferation in cancer cells. Many malignant tumor cells always display glutamine addiction. The “kidney-type” glutaminase (GLS1) is a metabolism enzyme which plays a significant part in glutaminolysis. Interestingly, GLS1 is often overexpressed in highly proliferative cancer cells to fulfill enhanced glutamine demand. So far, GLS1 has been proved to be a significant target during the carci nogenesis process, and emerging evidence reveals that i...
ConclusionsRGS14 KO mice exhibited anti-correlated locomotor responses to novelty and cocaine, but displayed increased thigmotaxis in response to either stimuli which was augmented by their combination. Our findings also suggest RGS14 may reduce neuronal activity in limbic subregions by inhibiting ERK-dependent signaling.
Notice NOT-DA-21-083 from the NIH Guide for Grants and Contracts
Physicians and lawyers together recruited homeless people and drug addicts to scam insurance companies. Do sales reps belong in the operating room? This high-risk specialty lowered its claim rates.Medscape Medical News
The World Food Programme distributing food in El Salvador. The second of the UN's 17 Sustainable Development Goals is to end hunger, achieve food security and improved nutrition and promote sustainable agriculture. Credit: WFP/David FernandezBy Trish CotterMELBOURNE, Sep 21 2021 (IPS) COVID-19 has exposed serious vulnerabilities in how people around the world access and consume food. One of the more alarming trends is the significant increase in the consumption of foods that may be tasty and convenient, but harm our heath. These ultra-processed products include sugary drinks, snack foods, frozen meals, packaged breads and ...
Activity-driven changes in the neuronal surface glycoproteome are known to occur with synapse formation, plasticity and related diseases, but their mechanistic basis and significance are unclear. Here, we observed thatN-glycans on surface glycoproteins of dendrites shift from immature to mature forms containing sialic acid in response to increased neuronal activation. In exploring the basis of theseN-glycosylation alterations, we discovered they result from the growth and proliferation of Golgi satellites scattered throughout the dendrite. Golgi satellites that formed during neuronal excitation were in close association wi...
ConclusionsThe present findings suggest that externalizing behavioral difficulties and problematic smartphone use are mutually dependent in the long term.
An excerpt from The Addicted Child: A Parent’s Guide to Adolescent Substance Abuse. How do you know if your teen has a substance problem? The inability to control substance use despite negative consequences is a classic definition of a severe substance use disorder. But substances aren’t the only thing afflicting adolescents. Another dangerous behavior isRead more …Self-harm and eating disorders in teens originally appeared inKevinMD.com.
Observe differences in body fat, diet quality, and food addiction and security between former heroin users and non-heroin users in the Hispanic population.
The ongoing opioid crisis, centered in the United States, demands new insights into the complex and largely unknown mechanisms of opioid tolerance and addiction. Opioids, ranging from the natural opiates such as morphine to synthetic alternatives such as fentanyl, are widely used in the clinic as analgesics for acute and chronic pain. However, long-term administration of opioids may result in tolerance development and thus increase the risk of overdose and death. Broad availability of both prescription and illegal opioids has fueled substance use disorders.