Post-Ebola Syndrome, Sierra Leone.

Post-Ebola Syndrome, Sierra Leone. Emerg Infect Dis. 2016 Apr;22(4):641-6 Authors: Scott JT, Sesay FR, Massaquoi TA, Idriss BR, Sahr F, Semple MG Abstract Thousands of persons have survived Ebola virus disease. Almost all survivors describe symptoms that persist or develop after hospital discharge. A cross-sectional survey of the symptoms of all survivors from the Ebola treatment unit (ETU) at 34th Regimental Military Hospital, Freetown, Sierra Leone (MH34), was conducted after discharge at their initial follow-up appointment within 3 weeks after their second negative PCR result. From its opening on December 1, 2014, through March 31, 2015, the MH34 ETU treated 84 persons (8-70 years of age) with PCR-confirmed Ebola virus disease, of whom 44 survived. Survivors reported musculoskeletal pain (70%), headache (48%), and ocular problems (14%). Those who reported headache had had lower admission cycle threshold Ebola PCR than did those who did not (p
Source: Emerging Infectious Diseases - Category: Infectious Diseases Authors: Tags: Emerg Infect Dis Source Type: research

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Discussion Dengue is an important arboviral infection that affects about 40% of the world population. It is found mainly in topical and subtropical areas of the world mainly in developing countries but it range is spreading including the United States. A review of common arboviruses can be found here. It is a flaviavirus with 4 distinct serotypes named DENV-1 through DENV-4 and is spread by A. aegypti a day biting mosquito. Infection with one serotype confers immunity to that serotype but not the others. It does offer some protection for cross-infection but this only lasts a few months. Incubation period is 3-14 days with ...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Adriano Queiroz1, Isabella Fernanda Dantas Pinto2, Maricélia Lima3, Marta Giovanetti1,4, Jaqueline Goes de Jesus1, Joilson Xavier1, Fernanda Khouri Barreto5, Gisele André Baptista Canuto6, Helineide Ramos do Amaral7, Ana Maria Bispo de Filippis4, Denise Lima Mascarenhas8, Melissa Barreto Falcão8, Normeide Pedreira Santos8, Vasco Ariston de Carvalho Azevedo9, Marcos Yukio Yoshinaga2*, Sayuri Miyamoto2 and Luiz Carlos Junior Alcantara1,4,10* 1Laboratório de Patologia Experimental, Instituto Gonçalo Moniz, Salvador, Brazil 2Departamento de Bioquímica, Instituto de Quími...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Introduction Lassa fever (LF) is a severe acute viral hemorrhagic illness caused by a virus belonging to the family Arenaviridae.1,2 The disease was first discovered in Sierra Leone in the 1950s, but the aetiological agent was first isolated after an outbreak of the disease in a village called Lassa in Borno State, Nigeria claiming the lives of two foreign missionary nurses in 1969.3 The virus exhibits persistent, asymptomatic infection, with profuse urinary virus excretion in Mastomys natalensis rodents, which serve as the natural reservoir.1,2 The virus is shed in their excreta (urine and faeces) of the rodent which can...
Source: PLOS Currents Outbreaks - Category: Epidemiology Authors: Source Type: research
A mysterious illness has killed 13 people and sickened 30 others in Liberia since April 23, according to the World Health Organization. Dr. Alex Gasasira, the WHO’s representative in Liberia, told HuffPost on Saturday that while authorities have not found the “smoking gun” of what has caused the unexplained illnesses and deaths in Sinoe County, Grand Bassa County and the capital city of Monrovia, all signs seem to point to an accidental “poisoning event” of some sort. The WHO said on Friday that all tests have come back negative for Ebola or Lassa fever. Of those that have died, 12 attend...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
The 2014–2015 Ebola epidemic affected several African countries, claiming more than 11,000 lives and leaving thousands with ongoing sequelae. Safe and effective vaccines could prevent or limit future outbreaks. The recombinant vesicular stomatitis virus–vectored Zaire Ebola (rVSV-ZEBOV) vaccine has shown marked immunogenicity and efficacy in humans but is reactogenic at higher doses. To understand its effects, we examined plasma samples from 115 healthy volunteers from Geneva who received low-dose (LD) or high-dose (HD) vaccine or placebo. Fifteen plasma chemokines/cytokines were assessed at baseline and on day...
Source: Science Translational Medicine - Category: Biomedical Science Authors: Tags: Research Articles Source Type: research
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Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
Ebola virus disease (EVD) survivors often complained of headache, musculoskeletal pain, and ocular symptoms during the weeks after they tested negative for the virus, according to an analysis of...
Source: Hospitalist News - Category: Hospital Management Source Type: research
Ebola virus disease (EVD) is a viral haemorrhagic fever, with a case fatality rate of 50% (25–90%). The current outbreak in West Africa (Guinea, Sierra Leone and Liberia) is the largest and most complex since the Ebola virus was discovered. Ebola spreads via direct contact with bodily fluids of infected people, and materials contaminated with these fluids. Healthcare workers have frequently been infected while treating patients with EVD. This has occurred through close contact with patients when infection control precautions were not strictly practised. One year into the current epidemic of EVD, there have been more ...
Source: Archives of Disease in Childhood - Category: Pediatrics Authors: Tags: Diarrhoea, Epidemiologic studies, Tropical medicine (infectious diseases), Headache (including migraine), Pain (neurology), Adolescent health, Child health, Neonatal and paediatric intensive care, Paediatric intensive care, Screening (epidemiology), Scree Source Type: research
Commentary on: WHO Ebola Response Team. Ebola virus disease in West Africa—the first 9 months of the epidemic and forward projections. N Engl J Med 2014;371:1481–95. Context An outbreak of Ebola virus disease (EVD), caused by Zaire ebolavirus, beginning in south-eastern Guinea in December 2013,1 but not formally identified until 23 March 2014, has spread to the neighbouring countries of Liberia, Sierra Leone and Mali, with limited transmission to Nigeria, USA, Spain and Senegal. The cumulative total of cases and deaths is 14 413 and 5177, respectively as of 11 November 2014, making this outbreak aroun...
Source: Evidence-Based Medicine - Category: Internal Medicine Authors: Tags: EBM Prognosis, Neurogastroenterology, Tropical medicine (infectious diseases), Headache (including migraine), Pain (neurology), Eating disorders Source Type: research
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