Nigeria: HIV-Mad Cow-Ebola-Lassa-Zika

[Daily Trust] When I was growing up in Sokoto in the early 1970s, a dishevelled local musician called Shu'aibu Tsamaye used to go from house to house, with a kalangu drum slung on his shoulder, playing his popular tunes. Shu'aibu's best known tunes were about drug addiction which in those days mostly involved kwaya [amphetamines], kapso [capsules], roka [rocket] and aisin [ICD]. He also had a popular song about the Udoji salary awards.
Source: AllAfrica News: HIV-Aids and STDs - Category: Infectious Diseases Source Type: news

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In the last 3 years the numbers of forcibly displaced people around the world has reached a record high. Experiences of war, persecution, violence, torture, participating in the killing of others, disruptions of attachments, and emotional losses increase the risk for psychological distress and may contribute to the risk of developing psychiatric and substance abuse disorders. The authors review the existing psychiatric literature on refugees, discuss the sociological reasons that explain the recent crisis, describe the psychiatric consequences, the risk factors and protective factors of the refugee experience, narrate the ...
Source: Addictive Disorders and Their Treatment - Category: Addiction Tags: Original Article Source Type: research
Gambling disorder is a pathologic condition, resulting from the interaction of multiple risk factors. Among these, dopamine neurotransmission is known for playing a significant role, as seen, for example, in patients using dopamine replacement therapy prescribed for Parkinson disease, in which gambling is considered to be iatrogenic. Considering this, together with the general mechanism of action of antipsychotic drugs, growing attention has recently been dedicated to Aripiprazole and to its partial dopaminergic agonism (reducing D2-receptor hyperactivation in the mesolimbic pathway and improving D2-receptor stimulation in...
Source: Addictive Disorders and Their Treatment - Category: Addiction Tags: Case Report Source Type: research
Conclusions: High dependence on sexual partner and risky injection behaviors among female who inject drugs were identified. Study findings contextualized with gender vulnerabilities in Colombia are fundamental for prevention/intervention efforts aimed at helping this at-risk population in the country and in Latin America.
Source: Addictive Disorders and Their Treatment - Category: Addiction Tags: Original Articles Source Type: research
Conclusions: Interinstitutional coordination should be promoted through joint meetings, and also training classes on disaster management and its implementation should be held. Moreover, up-to-date clinical protocols must be accessible to personnel, and facilities and resources needed in the disaster should be provided.
Source: Addictive Disorders and Their Treatment - Category: Addiction Tags: Original Articles Source Type: research
Conclusions: Identifying the risk factors for psychiatric comorbidity in patients with substance dependence highlights the importance of developing a dual diagnosis service to meet the needs of this population.
Source: Addictive Disorders and Their Treatment - Category: Addiction Tags: Original Articles Source Type: research
Conclusions: Those receiving hypnotherapy did marginally better concerning alcohol use at 1-year follow-up. This small advantage for hypnotherapy could indicate an effect, rendered nonsignificant by an underpowered study. It could also be that neither MI nor hypnotherapy gave an additional effect on top of the substantial group therapy. Lastly the findings could indicate that hypnotherapy is at least as effective as MI.
Source: Addictive Disorders and Their Treatment - Category: Addiction Tags: Original Articles Source Type: research
Conclusions: Substance abuse affects male sexual functions negatively. There are limited studies about the effects of substance abuse on male sexual functions in our country. For this reason, there is a need for more extensive prospective studies.
Source: Addictive Disorders and Their Treatment - Category: Addiction Tags: Original Articles Source Type: research
Publication date: 15 October 2019Source: Biosensors and Bioelectronics, Volume 143Author(s): Shofarul Wustoni, Shaofei Wang, Juan R. Alvarez, Tania C. Hidalgo, Suzana P. Nunes, Sahika InalAbstractAlzheimer's disease (AD) is a progressive neurodegenerative disease associated with severe memory loss and impaired cognitive skills. A common pathological change found in AD-affected brains is the accumulation of a peptide named amyloid-β (Aβ) that can form plaques. Aβ aggregates are visible to structural scanning tools; however, these bulky and expensive instruments are accessible to trained personnel in clinical ...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Conclusions: Up-regulation of MEG3 attended to the morphine-caused autophagy of HT22 cells might be through elevating c-fos expression and promoting ERK pathway activation. More experiments are also needed in the future to analyse the influence of other lncRNAs in drug addiction. PMID: 31433241 [PubMed - in process]
Source: Pharmaceutical Biology - Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research
In this study we investigated the effect of adolescent nicotine treatment on development of morphine tolerance and dependence as well as LPGi neuronal responses to morphine during adulthood.Male Wistar rats received subcutaneous injections of either nicotine or saline during adolescence and then development of morphine tolerance and dependence was assessed during adulthood by tail-flick and withdrawal tests, respectively. In vivo single-unit recording was performed to examine the LPGi neuronal activities.Results indicated that adolescent nicotine exposure significantly facilitates the development of tolerance to analgesic ...
Source: Life Sciences - Category: Biology Source Type: research
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