5 Questions with Oncology Social Worker Ashley Varner

Source: American Cancer Society :: News and Features - Category: Cancer & Oncology Source Type: news

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Publication date: Available online 11 August 2020Source: Journal of Oral BiosciencesAuthor(s): Sho Akashi, Takashi Nishida, Tomomi Mizukawa, Kazumi Kawata, Masaharu Takigawa, Seiji Iida, Satoshi Kubota
Source: Journal of Oral Biosciences - Category: Biomedical Science Source Type: research
Publication date: Available online 11 August 2020Source: Carbohydrate PolymersAuthor(s): Sevil Vaghefi Moghaddam, Fatemeh Abedi, Effat Alizadeh, Behzad Baradaran, Nasim Annabi, Abolfazl Akbarzadeh, Soodabeh Davaran
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Publication date: Available online 11 August 2020Source: Carbohydrate PolymersAuthor(s): Jingwen Luo, Tao Gong, Lixin Ma
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Publication date: July 2020Source: Biomedical and Environmental Sciences, Volume 33, Issue 7Author(s): Fei Ran WEI, Li Lin XIONG, Wei LI, Xue Rong WANG, Xin HONG, Bao An CHEN
Source: Biomedical and Environmental Sciences - Category: Biomedical Science Source Type: research
NF-κB transcription factors, driven by the IRAK/IKK cascade, confer treatment resistance in pancreatic ductal adenocarcinoma (PDAC), a cancer characterized by near-universal KRAS mutation. Through reverse-phase protein array and RNA sequencing we discovered that IRAK4 also contributes substantially to MAPK activation in KRAS-mutant PDAC. IRAK4 ablation completely blocked RAS-induced transformation of human and murine cells. Mechanistically, expression of mutant KRAS stimulated an inflammatory, autocrine IL-1β signaling loop that activated IRAK4 and the MAPK pathway. Downstream of IRAK4, we uncovered TPL2 (also k...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Cachexia, a devastating wasting syndrome characterized by severe weight loss with specific losses of muscle and adipose tissue, is driven by reduced food intake, increased energy expenditure, excess catabolism, and inflammation. Cachexia is associated with poor prognosis and high mortality and frequently occurs in patients with cancer, chronic kidney disease, infection, and many other illnesses. There is no effective treatment for this condition. Hypothalamic melanocortins have a potent and long-lasting inhibitory effect on feeding and anabolism, and pathophysiological processes increase melanocortin signaling tone, leadin...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Publication date: Available online 9 August 2020Source: The Journal of Steroid Biochemistry and Molecular BiologyAuthor(s): María Julia Ferronato, Serrano Mercedes Nadal, Enrique Javier Arenas Lahuerta, Cristina Bernadó Morales, Giuliana Paolillo, Aliguer Alex Martinez-Sabadell, Marilina Mascaró, Cristian Vitale, Yagamare Fall, Joaquín Arribas, María Marta Facchinetti, Alejandro Carlos Curino
Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research
Publication date: Available online 6 August 2020Source: Chemico-Biological InteractionsAuthor(s): Yoke Ying Tan, Pui Khee Yap, Griselda Loo Xin Lim, Meenu Mehta, Yinghan Chan, Sin Wi Ng, Deepak N. Kapoor, Poonam Negi, Krishnan Anand, Sachin Kumar Singh, Niraj Kumar Jha, Lay Cheng Lim, Thiagarajan Madheswaran, Saurabh Satija, Gaurav Gupta, Kamal Dua, Dinesh Kumar Chellappan
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
Publication date: Available online 8 August 2020Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Chenglei Li, Hong Guan, Zhaohuan Li, Fangqing Wang, Jingliang Wu, Bo Zhang
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
Publication date: Available online 7 August 2020Source: TrAC Trends in Analytical ChemistryAuthor(s): Migisha NtwaliP.V, Chae EunHeo, Jong Yoon Han, Soo Yeon Chae, Minji Kim, Hung M. Vu, Min-Sik Kim, Hugh I. Kim
Source: TrAC Trends in Analytical Chemistry - Category: Chemistry Source Type: research
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