Nigeria: Lassa Fever - Lagos Records First Case

[Daily Trust] Lagos -Lagos State has recorded its first case of the latest outbreak of Lassa fever. The incident was recorded at the Lagos University Teaching Hospital (LUTH), Idi-Araba.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news

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This article provides the epidemiology of the LF and lessons learnt from the investigation of the outbreak.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: 0627 Source Type: research
Background: Lassa fever (LF) is endemic in Nigeria. Outbreaks usually begin in communities however, substandard Infection Prevention and Control (IPC) practices can cause secondary infection in Health Care Workers (HCW). We assessed the knowledge of LF among community members where 2 cases occurred and HCW at the facility where cases were managed to identify knowledge gaps.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: 0625 Source Type: research
Background: The burden of undiagnosed febrile illness in low and middle-income countries is high and infectious diseases remain the leading cause of morbidity and mortality. The aetiology of systemic febrile illness and sepsis are particularly badly described partly because many pathogens cause a similar initial clinical presentation. In early 2018, Nigeria experienced its largest recorded outbreak of Lassa fever (LF). During this period of heightened transmission, there were 1,968 persons who met the clinical case definition for LF.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: 0560 Source Type: research
Background: Lassa virus (LASV) is endemic in several West African countries, causing seasonal outbreaks. While about 80% of infections are asymptomatic, it can result in severe haemorrhagic fever. The disease incidence has been increasing each year, with more than 700 confirmed cases in 2019. As identified in the WHO R&D Blueprint, there is a lack of, and therefore a need, to develop effective treatments and vaccines. The availability of an antibody reference reagent early in this process is of value, allowing assay harmonisation by calibration to the reference which is given an arbitrary unitage.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: 0551 Source Type: research
Background: Lassa fever (LF) is an acute viral hemorrhagic fever with dire public health consequences. Bauchi State outbreak of LF in 2019 with 5 LGAs having confirmed cases. We investigated to identify cases and the contacts so as to interrupt the transmission of LF.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: 0532 Source Type: research
In the last decades, a number of infectious viruses have emerged from wildlife or re-emerged, generating serious threats to the global health and to the economy worldwide. Ebola and Marburg hemorrhagic fevers, Lassa fever, Dengue fever, Yellow fever, West Nile fever, Zika, and Chikungunya vector-borne diseases, Swine flu, Severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and the recent Coronavirus disease 2019 (COVID-19) are examples of zoonoses that have spread throughout the globe with such a significant impact on public health that the scientific community has been called for a rapid int...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
This study suggests that LASV infections is an important cause of death in humans and that LASV are common in humans, rodents and other mammals in sub-Saharan Africa. These estimates highlight disparities between s ub-regions, and population risk profiles. Western Africa, and specific key populations were identified as having higher LASV CFR and prevalence, hence, deserving more attention for cost-effective preventive interventions.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Purpose of review To highlight the lessons learned from the Ebola outbreak that may inform our approach to the COVID-19 pandemic, particularly related to the widespread disruption of healthcare, ophthalmic disease manifestations, and vision health systems strengthening for future outbreaks. Recent findings Coronavirus disease 2019 (COVID-19), first detected in China in December 2019, has become a worldwide health emergency, with significant disruption of all aspects of society, including travel, business, and medical care. Although this pandemic has had unprecedented effects on healthcare delivery in the United States...
Source: Current Opinion in Ophthalmology - Category: Opthalmology Tags: COVID19: Edited by Allen Chiang and Prithvi Mruthyunjaya Source Type: research
[Nigeria Health Watch] Two hundred and nineteen (219) - That is the number of lives lost to Lassa fever between January and June 2020, according to the latest data from the Nigeria Centre for Disease Control (NCDC). Nigeria has been experiencing a yearly outbreak of the viral haemorrhagic fever since it was first identified in Borno state in 1969. However, the 2020 outbreak happened to be the largest with 1040 confirmed cases across 27 states, with Case Fatality Rate (CFR) of 21%. In 2019, the country recorded 810 confirmed case
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
oster Endemic to West Africa and South America, mammalian arenaviruses can cross the species barrier from their natural rodent hosts to humans, resulting in illnesses ranging from mild flu-like syndromes to severe and fatal haemorrhagic zoonoses. The increased frequency of outbreaks and associated high fatality rates of the most prevalent arenavirus, Lassa, in West African countries, highlights the significant risk to public health and to the socio-economic development of affected countries. The devastating impact of these viruses is further exacerbated by the lack of approved vaccines and effective treatments. Differe...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
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