Sudan: Smallpox Breaks Out in Eastern Chad Refugee Camp

[Radio Dabanga]Farchana -Cases of smallpox are increasing in the Farchana refugee camp in eastern Chad. The camp is short of medicines. Speaking to Radio Dabanga, Abu Bakar Ahmed Abdallah, the deputy head of the Farchana camp, reported that the first cases of smallpox appeared two weeks ago.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news

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Smith Widespread vaccination programmes led to the global eradication of smallpox, which was certified by the World Health Organisation (WHO), and, since 1978, there has been no case of smallpox anywhere in the world. However, the viable variola virus (VARV), the causative agent of smallpox, is still kept in two maximum security laboratories in Russia and the USA. Despite the eradication of the disease smallpox, clandestine stocks of VARV may exist. In a rapidly changing world, the impact of an intentional VARV release in the human population would nowadays result in a public health emergency of global concern: vaccin...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Yes. However, very probably not because of the novel coronavirus that has appeared in China. This seems to be front page headlines in every media outlet on the planet, and  the World Health Organization has convened a meeting to decide whether to declare an official Global Health Emergency.This sort of flapdoodle happens every time a novel pathogen appears. Back when I lived in the Hub of the Universe a mosquito-borne disease called West Nile virus appeared (having formerly been large confined to, yes, west of the Nile). For weeks, every time a new case was identified it would be on the front page of the Boston Globe....
Source: Stayin' Alive - Category: American Health Source Type: blogs
Abstract Forty years after the last endemic smallpox case, variola virus (VARV) is still considered a major threat to humans due to its possible use as a bioterrorism agent. For many years the risk of disease reemergence was thought to solely be through deliberate misuse of VARV strains kept in clandestine laboratories. However, recent experiments using synthetic biology have proven the feasibility of recreating a poxvirus de novo, implying that VARV could, in theory, be resurrected. Because of this new perspective the WHO Advisory Committee on VARV Research released new recommendations concerning research on poxv...
Source: Antimicrobial Agents and Chemotherapy - Category: Microbiology Authors: Tags: Antimicrob Agents Chemother Source Type: research
Title: HIV Triggers Immune System 'Amnesia' to Smallpox: StudyCategory: Health NewsCreated: 1/9/2020 12:00:00 AMLast Editorial Review: 1/10/2020 12:00:00 AM
Source: MedicineNet HIV General - Category: Infectious Diseases Source Type: news
THURSDAY, Jan. 9, 2020 -- HIV infection causes a loss of immunity to smallpox, even in people who were vaccinated as kids and are taking antiretroviral drugs to restore their immune system, a new study finds. Such " HIV-associated immune amnesia " ...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Abstract The history of Giovanni Falconi's career and his vaccination campaigns is two hundred years old. It is however very relevant today because of the widespread negative social opinion against vaccination at that time, opinions which seem to have re-emerged even in the current century. In his very important role of "Vaccine Conservator" (a sort of national supervisor for the quality of vaccinations), he clashed with the prejudice of the people and with the anti-scientific attitudes of some of his illustrious colleagues. He investigated how to simplify the procedure with a smallpox needle that became...
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
WEDNESDAY, Jan. 8, 2020 -- HIV-infected patients lose immunity to smallpox despite childhood vaccination and immune reconstitution with antiretroviral therapy, according to a study published online Dec. 23 in The Journal of Infectious...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
(Oregon Health&Science University) HIV patients lose immunity to smallpox even though they were vaccinated against the disease as children and have had much of their immune system restored with antiretroviral therapy, according to a study published in the Journal of Infectious Diseases. Called HIV-associated immune amnesia, the finding could explain why people living with HIV still tend to have shorter lives on average than their HIV-negative counterparts despite being on antiretroviral therapy.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Historians of public health estimate that throughout human history malaria, tuberculosis, and smallpox have killed more people than the plague. But discussion of plague often evokes a deep visceral fear, since plague has taken the lives of hundreds of millions over the centuries, usually in dramatic and socially disruptive pandemics linked to international trade.
Source: Mayo Clinic Proceedings - Category: Internal Medicine Authors: Tags: Stamp vignette on medical science Source Type: research
Abstract Following vaccinia vaccination, vesicle formation at the site occurs in 95% of primary vaccinees and is thought to indicate virus replication and vaccine efficacy. Little is known about virus replication and immune response in those who do not develop a vesicle. We used PCR to detect vaccinia in various sites following receipt of the smallpox vaccine in those with and without vesicle formation. Among 80 participants, 74 developed and 6 failed to develop a vesicle. Vaccinia DNA was detected in the blood, in the oropharynx, on the dressing, and on the hands of 5%, 11%, 4%, and 0% of those with vesicle forma...
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
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