The burden of major adverse cardiac events and antiplatelet prevention in patients with coronary or peripheral arterial disease

ConclusionDespite gaps in the literature, this assessment showed that MACE's risk is substantial among CAD or PAD patients and that the use of preventive therapies is suboptimal. Development of additional preventive therapies for these patients is warranted.This article is protected by copyright. All rights reserved.
Source: Cardiovascular Therapeutics - Category: Cardiology Authors: Tags: Unsolicited Review Source Type: research

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Sungjin Chung, Soojeong Kim, Mina Son, Minyoung Kim, Eun Sil Koh, Seok Joon Shin, Seung-Hyun Ko, Ho-Shik Kim
Source: Frontiers in Physiology - Category: Physiology Source Type: research
The National Institutes of Health (NIH) would receive $34.4 billion in FY 2020, roughly $4.7 billion or 13 percent below the levels enacted by Congress for FY 2019, according to the President’s Budget released on March 11. The budget for NIH includes $492 million in funding made available through the 21st Century Cures Act and $150 million in mandatory funding. The leading biomedical research agency in the world would receive budget cuts across the board. All NIH centers are slated for budget reductions: National Cancer Institute: -8.7 percent National Heart, Lung, and Blood Institute: -14 percent National Inst...
Source: Public Policy Reports - Category: Biology Authors: Source Type: news
Ischemic stroke is a predominant cause of disability worldwide, with thrombolytic or mechanical removal of the occlusion being the only therapeutic option. Reperfusion bears the risk of an acute deleterious calcium-dependent breakdown of the blood-brain barrier. Its mechanism, however, is unknown. Here, we identified type 5 NADPH oxidase (NOX5), a calcium-activated, ROS-forming enzyme, as the missing link. Using a humanized knockin (KI) mouse model and in vitro organotypic cultures, we found that reoxygenation or calcium overload increased brain ROS levels in a NOX5-dependent manner. In vivo, postischemic ROS formation, in...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Resumo O objetivo deste artigo é analisar a tendência da mortalidade na população de 5 a 69 anos, residente na região Sudeste e Unidades Federadas (UF), utilizando-se a “ Lista Brasileira de Causas de Mortes Evit áveis ” . Estudo ecol ógico de séries temporais da taxa de mortalidade padronizada por causas evitáveis e não evitáveis, com correções para as causas mal definidas e o sub-registro de óbitos informados, no período de 2000 a 2013. Evidenciou-se o declínio da taxa de mortalidade na populaç...
Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research
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Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research
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Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research
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Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research
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Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research
AbstractThe purpose of this project was to develop a multidimensional understanding of synergistic connections between food-related and emotional health in the lives of Latina immigrants using a community-engaged approach with women who participate in a social isolation support group. The domains of interest included the intersection of social isolation, depression, diabetes, and food insecurity. We tested an innovative “structured dialogue” (SD) approach to integrating the domains of interest into the group dynamic. We documented key positive impacts of participation in the group on women’s everyday expe...
Source: Journal of Racial and Ethnic Health Disparities - Category: International Medicine & Public Health Source Type: research
AbstractMany healthcare providers lack the awareness of health disparities among their patients that precedes action to improve outcomes. Limited health disparities training is a probable contributor. We assessed primary care residents ’ awareness of racial and ethnic disparities in diabetes, their perceived preparedness to discuss health disparities with patients, and their preferences for training and resources to improve their preparedness. Primary care residents (n = 98) affiliated with two teaching hospitals in North Carolina were invited to complete a 20-question health disparities survey. Fifty-t...
Source: Journal of Racial and Ethnic Health Disparities - Category: International Medicine & Public Health Source Type: research
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