Level of circulating endothelial cells and expression of nuclear factor kappa beta of human's peripheral blood mononuclear cells in subjects with certain conditions.

CONCLUSION: increase of level CEC and NFκB expression has a strong relationship with vascular disease and its risk factors. PMID: 24760806 [PubMed - indexed for MEDLINE]
Source: Acta medica Indonesiana - Category: Internal Medicine Tags: Acta Med Indones Source Type: research

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AbstractThe study proposes a novel machine learning (ML) paradigm for cardiovascular disease (CVD) detection in individuals at medium to high cardiovascular risk using data from a Greek cohort of 542 individuals with rheumatoid arthritis, or diabetes mellitus, and/or arterial hypertension, using conventional or office-based, laboratory-based blood biomarkers and carotid/femoral ultrasound image-based phenotypes. Two kinds of data (CVD risk factors and presence of CVD —defined as stroke, or myocardial infarction, or coronary artery syndrome, or peripheral artery disease, or coronary heart disease) as ground truth, wer...
Source: Rheumatology International - Category: Rheumatology Source Type: research
Clin Exp Hypertens. 2022 Jan 3:1-9. doi: 10.1080/10641963.2021.2022688. Online ahead of print.ABSTRACTIn 2020, the National Center for Cardiovascular Diseases with National Committee on Hypertension Management in Primary Health Care in China issued revised national clinical practice guidelines on the management of hypertension in primary health care based on the 2018 Chinese guidelines for the management of hypertension. To evaluate adherence to the guidelines, this retrospective study assessed the real-world status of antihypertensive drug prescribing for Chinese patients with hypertension, classified by comorbidity: coro...
Source: Clinical and Experimental Hypertension - Category: Cardiology Authors: Source Type: research
Ann Palliat Med. 2021 Nov;10(11):11539-11547. doi: 10.21037/apm-21-2666.ABSTRACTBACKGROUND: Carotid artery stenosis (CAS) is one of the leading causes of ischemic stroke. However, knowledge of the changes in the plaque itself is lacking. Information about the ultrasound and clinical features of CAS will help elucidate the changes in prognostic and risk factors.METHODS: We evaluated 736 patients with carotid stenosis for an average 18-month follow-up. According to their degree of CAS stenosis, patients were allocated to one of three groups: regression (n=125), stable (n=443), or progression (n=168). An ordinal regression an...
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research
Abstract: Little recent data are available about the patterns of prescription for fibrates in patients followed in primary care practices. Therefore, the goal of this study was to analyze the prevalence of and the factors associated with the use of fibrates among patients receiving lipid-lowering drugs in Germany. The study included patients aged ≥18 years with at least 1 visit to 1 of 1070 general practices in Germany between January and December 2019. Lipid-lowering drugs included statins (without and with ezetimibe) and fibrates. The prevalence of the prescription of fibrates corresponded to the number of patient...
Source: Journal of Cardiovascular Pharmacology - Category: Cardiology Tags: Original Article Source Type: research
Med Sci Monit. 2021 Nov 22;27:e932813. doi: 10.12659/MSM.932813.ABSTRACTBACKGROUND Atrial fibrillation (AF) is the most common persistent arrhythmia that can cause complications (including stroke). Therefore, its diagnosis and treatment require increased attention. Although beta-2 microglobulin (b2-MG) is a novel marker of cardiovascular disease, its role in AF has not been evaluated. MATERIAL AND METHODS We conducted a case-control study with 61 patients who had normal heart rhythm (control group) and 60 patients with AF (research group). We analyzed the serum b2-MG levels in both groups and performed multivariate analysi...
Source: Medical Science Monitor - Category: Research Authors: Source Type: research
ConclusionFrom our study we can conclude that diabetes mellitus as a risk factor in cases of stroke leads to increase complications and worsens the outcome in cases of stroke whether hemorrhagic or ischemic.RecommendationsFrom our study we recommended strict control of diabetes mellitus when present in cases of stroke to avoid bad outcome and to prevent complications in these cases.
Source: QJM - Category: Internal Medicine Source Type: research
Conclusion: Morbidity models and nomograms incorporating clinical and surgical data can be used to predict operative risk for esophagectomy and provide appropriate resources for the postoperative management of high-risk patients.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research
Introduction: Post-stroke cognitive impairment (PSCI) is common, but evidence on the impact of vascular risk factors is lacking. We explored the association between pre-stroke vascular risk factors and PSCI and studied the course of PSCI.Materials and Methods: Vascular risk factors were collected at baseline in stroke survivors (n = 635). Cognitive assessments of attention, executive function, memory, language, and the Montreal Cognitive Assessment (MoCA) were performed at 3 and/or 18 months post-stroke. Stroke severity was assessed with the National Institutes of Health Stroke Scale (NIHSS). PSCI was measured with global ...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Tuberculosis (TB) continues to be a major health problem in low- and middle-income countries (LMICs). In 2019, WHO estimated that there were 10 million new cases of TB, and 1.4 million deaths due to TB worldwide (World Health Organization, 2020). At the same time, LMICs face a rapid increase in the burden of noncommunicable diseases such as diabetes mellitus (DM) and cardiovascular diseases (CVD), including coronary heart disease and stroke. More than 75% of cardiovascular deaths occur in LMICs (World Health Organization, 2014).
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
Ann Med. 2021 Dec;53(1):1065-1073. doi: 10.1080/07853890.2021.1943514.ABSTRACTBACKGROUND: The liver fat score (LFS) has been proposed to be a simple non-invasive marker of non-alcoholic fatty liver disease (NAFLD), which is highly prevalent in the general population. We tested its association with cardiovascular diseases (CVDs) and prognosis.METHODS: 17,244 adult participants from the National Health and Nutrition Examination Survey 1999-2016 were included. LFS is calculated from variables including serum aspartate transaminase/alanine transaminase (AST/ALT) ratio, fasting serum aspartate transaminase (AST) level, fasting ...
Source: Annals of Medicine - Category: Internal Medicine Authors: Source Type: research
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