Magnesium Sulphate for Eclampsia and Fetal Neuroprotection: A Comparative Analysis of Protocols Across Canadian Tertiary Perinatal Centres.

CONCLUSION: This study suggests that local protocols are often inconsistent with published evidence. While this may be related to local institutional practices, relevant processes must be put in place to maximize uniformity of practice and improve patient care. PMID: 26629718 [PubMed - in process]
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research

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INTRODUCTION: In Canada, aviators and seafarers are required to be medically fit by international and domestic standards to be issued a medical certificate by Transport Canada (TC). In the event of denial or restriction, individuals have the right t...
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Source: Journal of Clinical and Experimental Neuropsychology - Category: Psychiatry & Psychology Authors: Source Type: research
Source: AIDS Care - Category: Infectious Diseases Authors: Source Type: research
Tomas’s mom developed pre-eclampsia, a hypertension disorder sometimes developed during pregnancy which can cause serious health risks for both mom and baby, during her fifth month of pregnancy. This high blood pressure pregnancy complication affects kidney and liver function and when left untreated, can lead to blood clotting failure, fluid buildup in the lungs, seizures and in severe cases, death. With this diagnosis, Tomas’s mom was put on immediate bed rest to try and relieve her pre-eclampsia symptoms. Just when she was feeling some relief, Tomas’s mom received the unfortunate news that her baby&rsqu...
Source: Cord Blood News - Category: Perinatology & Neonatology Authors: Tags: babies Cord Blood medical research pregnancy stem cells Source Type: blogs
In conclusion, the present meta-analysis shows that the youngest and sickest preterm infants are at higher risk of developing CBH. Our results highlight the multifactorial nature of CBH and reinforce the idea that cerebellar injury in very preterm newborns has important neurodevelopmental consequences among survivors.
Source: Frontiers in Physiology - Category: Physiology Source Type: research
​An 11-year-old boy with cerebral palsy presented to the emergency department unresponsive. His mother said the child was in his normal state earlier that morning, but was blue and unresponsive when she tried to wake him from his morning nap. A home pulse oximeter reported an oxygen level of 55%.The mother placed the child on oxygen and called 911. He was still unresponsive on arrival, and his physical examination demonstrated flaccid paralysis and a GCS score of 3 with fixed dilated pupils. He was tachycardic with shallow respirations. His initial vital signs were a temperature of 36.9°C, a heart rate of 136 bpm, a ...
Source: The Tox Cave - Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Marjon E. Feenstra1†, Mirthe H. Schoots2†, Torsten Plösch1, Jelmer R. Prins1, Sicco A. Scherjon1, Albertus Timmer2, Harry van Goor2 and Sanne J. Gordijn1* 1Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands 2Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands Objective: Management of late fetal growth restriction (FGR) is limited to adequate fetal monitoring and optimal timing of delivery. The Disproportionate Intrauterine Growth Intervention ...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
CONCLUSIONS: This overview summarises evidence from Cochrane reviews on the effects of antenatal and intrapartum interventions on cerebral palsy, and can be used by researchers, funding bodies, policy makers, clinicians and consumers to aid decision-making and evidence translation. We recommend that readers consult the included Cochrane reviews to formally assess other benefits or harms of included interventions, including impacts on risk factors for cerebral palsy (such as the reduction in intraventricular haemorrhage for preterm babies following exposure to antenatal corticosteroids).Magnesium sulphate for women at risk ...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
This article examines the available evidence, its interpretation and its translation into clinical practice.
Source: Obstetrics, Gynaecology and Reproductive Medicine - Category: OBGYN Authors: Tags: Ethics/education Source Type: research
AimPregnancy‐induced hypertension/pre‐eclampsia (PIH/PE) is associated with cerebral palsy (CP) in term births but if sufficiently severe to necessitate preterm delivery predicts a lower risk of CP than observed in gestational peers. We investigated whether this apparent ‘protection’ was attributable to inappropriately chosen comparison groups and/or an increased risk of perinatal death. MethodPerinatal information was collected from medical records of children with CP, individually matched neonatal survivors without CP, and representative samples of perinatal deaths of Western Australian birth cohorts from...
Source: Developmental Medicine and Child Neurology - Category: Child Development Authors: Tags: Original Article Source Type: research
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