Zimbabwe: Govt Remains Firm in Aids Fight

[The Herald] By establishing the AIDS Levy to fund the country's AIDS response and the National AIDS Council in 2000 to administer it and spearheading the multi-sectoral battle against the pandemic, the Zimbabwean Government showed that it was taking the threat posed by AIDS very seriously. But the narrative of the country's AIDS response would have been different if then Finance Minister Dr Simba Makoni had succeeded in his attempts to scrap the AIDS Levy.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news

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Abstract Human immunodeficiency virus type-1 (HIV-1) is the causative agent responsible for the acquired immunodeficiency syndrome (AIDS) pandemic. More than 60 million infections and 25 million deaths have occurred since AIDS was first identified in the early 1980s. Advances in available therapeutics, in particular combination antiretroviral therapy, have significantly improved the treatment of HIV infection and have facilitated the shift from high mortality and morbidity to that of a manageable chronic disease. Unfortunately, none of the currently available drugs are curative of HIV. To deal with the rapid emerg...
Source: Topics in HIV Medicine - Category: Infectious Diseases Authors: Tags: Curr Top Med Chem Source Type: research
Conclusion: The findings indicated that though the majority of the respondents had knowledge of HIV and AIDS, positive behavior change remained a challenge. Most respondents (88%) had one sexual partner with 38% reporting condom use during their last sexual encounter. HIV/AIDS awareness was widespread. However, there were still characteristics of resistance to behavior change, because there was evidence of underestimation of HIV risk through engagement in behavior, which contributed to HIV infection and spread.Behavioral change measures using the BCC model is proposed.Keywords: BCC Model, behavior change, HIV, AIDS, youth, Swaziland.
Source: African Health Sciences - Category: African Health Source Type: research
Publication date: December 2019Source: Microbial Pathogenesis, Volume 137Author(s): Faruq Abdulla, Utpal Kumar Adhikari, M. Kamal UddinAbstractTill now, AIDS, caused by the human immunodeficiency virus (HIV) is still a severe health problem worldwide. It weakens the immune system by targeting the T-helper cells. Specifically, the severity of the pandemic HIV-1 makes the emergence of an enduring effective vaccine against HIV-1. Therefore, we have applied a series of immunoinformatics approaches to the four conserved domains of HIV-1 integrase (IN) proteins to design an effective multi-epitope based subunit vaccine which mig...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
This study uses qualitative data from 20 in-depth interviews and one focus group to examine the risk behaviours of university students aged 18-24 years old, with particular emphasis on understanding the decline in the use of condoms. It is well documented that South Africa has one of the highest prevalence rates of HIV and AIDS in the world, however the findings of this study suggest that even though students were well informed about the perceived risks associated with unsafe sexual behaviours, they continue to engage in risk behaviours including unprotected sexual intercourse, multiple sexual partners and the use of alcoh...
Source: African Journal of AIDS Research - Category: African Health Tags: Afr J AIDS Res Source Type: research
By The Editorial Team, IntraHealth InternationalSeptember 13, 2019Over the course of our 40-year history, IntraHealth International has consistently designed creative solutions to health workforce challenges. From new technologies to old-fashioned human storytelling, we find new solutions to longstanding problems.  In a new technical publication, we highlight seven examples of how and why we look for new ways to get results. Here’s a sneak peak of what’s inside The Future of Global Health Starts Here: 7 Creative Approaches to Health Workforce Challenges. Funding the Nex...
Source: IntraHealth International - Category: International Medicine & Public Health Authors: Tags: Family Planning & Reproductive Health HIV AIDS Noncommunicable Diseases Digital Health Education Performance Policy Advocacy Health Workforce Systems Health Workers Source Type: news
Seminal amyloid fibrils are made up of naturally occurring peptide fragments and are key targets for the development of combination microbicides or antiviral drugs. Previously, we reported that the polysulfonic compound ADS-J1 is a potential candidate microbicide that not only inhibits HIV-1 entry, but also seminal fibrils. However, the carcinogenic azo moieties in ADS-J1 preclude its clinical application. Here, we screened several ADS-J1–like analogs and found that the antiparasitic drug suramin most potently inhibited seminal amyloid fibrils. Using various biochemical methods, including Congo red staining, CD analy...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Microbiology Source Type: research
Histoplasmosis is a systemic mycosis caused by the dimorphic fungus Histoplasma capsulatum, with disseminated histoplasmosis (HD) being one of its clinical forms. As a consequence of the HIV-AIDS pandemic, HD has become prevalent not only in regions that are recognized as endemic but also in areas not considered endemic, such as Europe and Asia. Its clinical manifestations are varied and mimic several infectious diseases, mainly tuberculosis. In endemic areas, it is the first manifestation of AIDS in 50 to 70% of patients. The diagnosis of histoplasmosis is difficult and HD can lead to death if not diagnosed early and if p...
Source: Dermatology Online Journal - Category: Dermatology Source Type: research
Two HIV virus types exist: HIV-1 is pandemic and aggressive, whereas HIV-2 is confined mainly to West Africa and less pathogenic. Despite the fact that it has been almost 40 years since the discovery of AIDS, ...
Source: AIDS Research and Therapy - Category: Infectious Diseases Authors: Tags: Review Source Type: research
es SL, Wejse C Abstract Two HIV virus types exist: HIV-1 is pandemic and aggressive, whereas HIV-2 is confined mainly to West Africa and less pathogenic. Despite the fact that it has been almost 40 years since the discovery of AIDS, there is still no cure or vaccine against HIV. Consequently, the concepts of functional vaccines and cures that aim to limit HIV disease progression and spread by persistent control of viral replication without life-long treatment have been suggested as more feasible options to control the HIV pandemic. To identify virus-host mechanisms that could be targeted for functional cure d...
Source: AIDS Research and Therapy - Category: Infectious Diseases Authors: Tags: AIDS Res Ther Source Type: research
CONCLUSIONS: STIs remain pandemic, and the availability of ART may have led to an increase in STIs, as fear of HIV has diminished. Classical STIs present a huge worldwide health burden that cannot be separated from HIV, and they deserve far more attention than they currently receive. PMID: 31468737 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
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