Acquisition of the lac operon by Salmonella enterica

Conclusions: Our results indicate that the lac region is highly mobile among Enterobacteriaceae and demonstrate that the Lac + S. enterica subsp. enterica serovars acquired the lac region through parallel events. The acquisition of the lac operon by several S. enterica serovars may be indicative of environmental adaptation by these bacteria.
Source: BMC Microbiology - Category: Microbiology Authors: Source Type: research

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Nontyphoidal Salmonella species are globally disseminated pathogens and are the predominant cause of gastroenteritis. The pathogenesis of salmonellosis has been extensively studied using in vivo murine models and cell lines, typically challenged with Salmonella enterica serovar Typhimurium. Although S. enterica serovars Enteritidis and Typhimurium are responsible for most of the human infections reported to the Centers for Disease Control and Prevention (CDC), several other serovars also contribute to clinical cases of salmonellosis. Despite their epidemiological importance, little is known about their infection phenotypes...
Source: Infection and Immunity - Category: Infectious Diseases Authors: Tags: Bacterial Infections Source Type: research
In this study, whole-genome sequence (WGS) data from a set of 46 Salmonella Agona including five isolates associated with the 1998 outbreak and 25 isolates associated with the 2008 outbreak were analyzed. From each outbreak one isolate was sequenced on the Pacific Biosciences RS II Sequencer to determine the complete genome sequence. We reconstructed a phylogenetic hypothesis of the samples using a reference-based method for identifying variable sites. Using Single Nucleotide Polymorphism (SNP) analyses, we were able to distinguish and separate Salmonella Agona isolates from both outbreaks with only a mean of eight SNP dif...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
By Jan LundiusSTOCKHOLM / ROME, Mar 19 2020 (IPS) The human factor is intimately involved in the origin, spread, and mitigation of the Coronavirus and we cannot afford to ignore that our future existence depends on compassion and cooperation. Response matters! Some quarantined Italians might recall Giovanni Boccaccio´s The Decameron from 1353 in which people escaping the plague are secluded in a villa where they tell stories to each other. Boccaccio introduced his collection of short stories with an eyewitness account of horrifying human suffering in Florence, which in 1348 was struck by a ”pestilence” t...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Global Headlines Health Humanitarian Emergencies TerraViva United Nations Women's Health Source Type: news
M. Jiang et al.
Source: Emerging Infectious Diseases Journal - Category: Infectious Diseases Source Type: research
Abstract A strain of extensively drug resistant (XDR) Salmonella Typhi has caused a large ongoing outbreak in Pakistan since 2016. In Ontario, Canada, ten cases of mainly bloodstream infections (n=9) were identified in patients who traveled to Pakistan. Whole genome sequencing showed that Canadian cases were genetically related to the outbreak strain. The appearance of XDR typhoid cases in Ontario prompted provincial wide alert to physicians to recommend carbapenems or azithromycin in suspected typhoid cases with travel history to Pakistan. PMID: 32122900 [PubMed - as supplied by publisher]
Source: Antimicrobial Agents and Chemotherapy - Category: Microbiology Authors: Tags: Antimicrob Agents Chemother Source Type: research
Conclusions: The higher prevalence of ESBL producingSalmonella typhi clinical strains raises the concern about transmission prevention and infection management in the community as well as clinical settings. Moreover, the study highlights the problem concerning the declining antibiotic arsenal for the therapeutic management of typhoid fever and the emergence and spread of XDR strains in Pakistan.
Source: The Journal of Infection in Developing Countries - Category: Infectious Diseases Source Type: research
FDA says fast-food chain "engaged in a pattern of receiving and offering for sale adulterated fresh produce."
Source: Health News: - Category: Consumer Health News Source Type: news
Here is what has sprouted since 2012.
Source: Healthcare News - Category: Pharmaceuticals Authors: Source Type: news
The U.S. Food and Drug Administration has issued a warning letter to sandwich chain Jimmy John's, accusing the company of selling fresh produce linked to five outbreaks of E. coli or salmonella in the past seven years.
Source: Health News - - Category: Consumer Health News Source Type: news
The US Food and Drug Administration has issued a warning letter to the Jimmy John's sandwich chain, saying certain vegetables it served were implicated in five outbreaks of E. coli or salmonella in the past seven years.
Source: - Health - Category: Consumer Health News Source Type: news
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