Recent HIV/AIDS News from NIAID

July 30, 2015: HVTN 505 Vaccine Induced Antibodies Nonspecific for HIV July 23, 2015: Two Paths Pave Way for Development of a Preventive HIV Vaccine July 21, 2015: Study Finds PrEP Use Feasible Among High-Risk Groups in U.S. Community Settings July 20, 2015: Dr. Fauci at IAS 2015: Comprehensive Global Prevention Can End HIV/AIDS Pandemic July 20, 2015: Early Antiretroviral Therapy Prevents Non-Aids Outcomes in HIV-Infected People, NIH-Supported Study Finds July 20, 2015: HIV Control Through Treatment Durably Prevents Heterosexual Transmission of Virus July 20, 2015: Young South African Women Can Adhere to Daily PrEP Regimen as HIV Prevention, Study Finds July 17, 2015: Cholesterol Metabolism in Immune Cells Linked to HIV Progression

Related Links:

Publication date: Available online 14 November 2019Source: The Lancet Global HealthAuthor(s): Karoun H Bagamian, John D Anderson, Farzana Muhib, Oliver Cumming, Lindsey A Laytner, Thomas F Wierzba, Richard RheingansSummaryBackgroundDiarrhoea, a global cause of child mortality and morbidity, is linked to adverse consequences including childhood stunting and death from other diseases. Few studies explore how diarrhoeal mortality varies subnationally, especially by cause, which is important for targeting investments. Even fewer examine indirect effects of diarrhoeal morbidity on child mortality. We estimated the subnational d...
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
Matthew O'Conner presented at Undoing Aging earlier this year on the startup biotech company Underdog Pharmaceuticals. The company is spinning out of the SENS Research Foundation (SRF), based on research conducted by the scientific team there in recent years. The company is focused on a class of molecule known cyclodextrins, and have candidates capable of efficiently binding and sequestering 7-ketocholesterol. This form of oxidized cholesterol is of great importance to the progression of atherosclerosis, and possibly other age-related conditions as well. In the case of atherosclerosis, the presence of oxidized cholesterols...
Source: Fight Aging! - Category: Research Authors: Tags: Healthy Life Extension Community Source Type: blogs
ConclusionsOur study demonstrated a sex-specific inverse effect of height on mortality from different major causes in rural Chinese adults.
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
Abstract Analysis of the Amino-peptidase N (APN) protein from Anopheles culicifacies as a vector based Transmission Blocking Vaccines (TBV) target has been considered for malaria vaccine development. Short peptides as potential epitopes for B cells and cytotoxic T cells and/or helper T cells were identified using prediction models provided by NetCTL and IEDB servers. Antigenicity determination, allergenicity, immunogenicity, epitope conservancy analysis, atomic interaction with HLA allele specific structure models and population coverage were investigated in this study. The analysis of the target protein helped to...
Source: Bioinformation - Category: Bioinformatics Authors: Tags: Bioinformation Source Type: research
Publication date: Available online 14 November 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Masoud Khosravipour, Mostafa Shahmohammadi, Hossein Valadi AtharAbstractBackgroundSome studies indicated night shift work can be associated with the higher risk of metabolic syndrome (MetS). However, the effects of both rotating and extended night shift work (12-hr rotating night) on MetS has not well-known. We aimed to examine and clarify the association among petrochemical workers.MethodsWe recruited 1575 eligible workers in this study. According to shift work schedules the participants we...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Authors: Hassing GJ, van der Wall HEC, van Westen GJP, Kemme MJB, Adiyaman A, Elvan A, Burggraaf J, Gal P Abstract Purpose: Elevated blood pressure induces electrocardiographic changes and is associated with an increase in cardiovascular disease later in life compared to normal blood pressure levels. The purpose of this study was to evaluate the association between normal to high normal blood pressure values (90-139/50-89 mmHg) and electrocardiographic parameters related to cardiac changes in hypertension in healthy young adults.Methods: Data from 1449 volunteers aged 18-30 years collected at our cent...
Source: Blood Pressure - Category: Hematology Tags: Blood Press Source Type: research
DiscussionDependent on animal model, both histopathological and biochemical end-points differed between sampling sites in the liver. Based on these findings, we recommend that sample site location is highly standardized and properly reported in order to minimize potential sampling variation and to optimize reproducibility and meaningful comparisons of preclinical studies of NAFLD.
Source: Journal of Pharmacological and Toxicological Methods - Category: Drugs & Pharmacology Source Type: research
This study was aimed at evaluating the antidiabetic activity of aqueous extract of Digitaria exilis grains in streptozotocin (STZ)-induced diabetic rats.Material and methodsForty two male rats (166.43 ± 3.32 g) were completely randomized into six groups (A-F) of 7 animals each. Animals in group A (control) were administered 0.5 ml of distilled water while those in groups B, C, D, E and F which were induced with diabetes mellitus (by intraperitoneal administration of 60 mg/kg body weight of STZ) were also administered distilled water, 50 mg/kg body weight of metformin (a reference antidiabetic drug), 50, ...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Conditions:   HIV/AIDS;   Depression;   Anxiety;   Post-traumatic Stress Disorder;   Substance Use Disorders Intervention:   Behavioral: Adapted Common Elements Treatment Approach Sponsors:   Michael J Mugavero, MD;   University of North Carolina, Chapel Hill Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Up until the first half of the twentieth century, large-scale health disasters were mostly due to natural causes (earthquakes, volcanoes, hurricanes, etc.) or infections (e.g., smallpox, influenza epidemics, cholera). But something peculiar happened as we entered the second half of the century: Health disasters due to natural causes became dwarfed by large-scale health disasters that are man-made. Here’s a list of the Six Worst U.S. Health Disasters of the Last 50 Years, mostly man-made phenomena that have exacted huge tolls: widespread disease, premature death, poorly managed (though nonetheless highly profitable fo...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Undoctored Wheat Belly Lifestyle autoimmune gluten grain-free grains Inflammation low-carb Weight Loss Source Type: blogs
More News: African Health | AIDS Vaccine | Cholesterol | Department of Health | Health | HIV AIDS | Infectious Diseases | Pandemics | Study | Vaccines | Women