Serum neuron specific enolase - a novel indicator for neuropsychiatric systemic lupus erythematosus?

Serum neuron specific enolase - a novel indicator for neuropsychiatric systemic lupus erythematosus? Lupus. 2015 Jun 29; Authors: Hawro T, Bogucki A, Krupińska-Kun M, Maurer M, Woźniacka A Abstract OBJECTIVE: Neuropsychiatric (NP) lupus, a common manifestation of systemic lupus erythematosus (SLE), is still insufficiently understood, in part, because of the lack of specific biomarkers. Neuron specific enolase (NSE), an important neuronal glycolytic enzyme, shows increased serum levels following acute brain injury, and decreased serum levels in several chronic disorders of the nervous system, including multi infarct dementia, multiple sclerosis and depression. The aim of the study was to evaluate serum NSE levels in SLE patients with and without nervous system involvement, and in healthy controls, and to assess the correlation of NSE serum levels of patients with neuropsychiatric systemic lupus erythematosus (NPSLE) with clinical parameters. METHODS: The study comprised 47 SLE patients and 28 controls. SLE activity was assessed using the Systemic Lupus Activity Measure (SLAM). A neurologist and a psychiatrist examined all patients. NP involvement was diagnosed according to strict NPSLE criteria proposed by Ainiala and coworkers, as modification to American College of Rheumatology (ACR) nomenclature and case definitions. NSE serum levels were determined by use of an immunoassay. RESULTS: Mean NSE serum concentrations in patients with NPSLE were...
Source: Lupus - Category: Rheumatology Authors: Tags: Lupus Source Type: research

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ObjectivesTo assess anxiety and depression in patients with incidental pulmonary nodules and analyze the related impact factors.MethodsAll patients were assessed by questionnaires for their anxiety and depression after incidentally found pulmonary nodules. Hospital anxiety and depression scale (HAD), generalized anxiety disorder scale ‐7 (GAD‐7), and multidimensional scale of perceived social support (MSPSS) were used to evaluate their anxiety and depression in order to understand the basic information and social support, and to analyze the related factors.ResultsThe HAD scale was used in 201 patients with pulmonary no...
Source: Thoracic Cancer - Category: Cancer & Oncology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Publication date: Available online 25 March 2020Source: Nanomedicine: Nanotechnology, Biology and MedicineAuthor(s): Ming-Jang Chiu, Ta-Fu Chen, Chaur-Jong Hu, Sui-Hing Yan, Yu Sun, Bing-Hsien Liu, Yun-Tsui Chang, Che-Chuan Yang, Shieh-Yueh Yang
Source: Nanomedicine: Nanotechnology, Biology and Medicine - Category: Nanotechnology Source Type: research
A significant proportion of healthcare workers treating patients exposed to COVID-19 have symptoms of depression, anxiety, and trouble sleeping.Medscape Medical News
Source: Medscape Psychiatry Headlines - Category: Psychiatry Tags: Psychiatry News Source Type: news
Source: Journal of Pain Research - Category: Anesthesiology Tags: Journal of Pain Research Source Type: research
Publication date: Available online 25 March 2020Source: NeuroscienceAuthor(s): Katsumasa Muneoka, Yasunori Oda, Masaaki Iwata, Masaomi Iyo, Kenji Hashimoto, Yukihiko Shirayama
Source: Neuroscience - Category: Neuroscience Source Type: research
CONCLUSION: There is sufficient evidence to propose light therapy in a bipolar depressive episode with or without seasonal features. PMID: 32207132 [PubMed - in process]
Source: Tijdschrift voor Psychiatrie - Category: Psychiatry Authors: Tags: Tijdschr Psychiatr Source Type: research
CONCLUSION: Although consensus is difficult to achieve given the ideological component, there are options. Three factors are critically important: confer to establish which data convince the opposition, response prediction (what works for whom), and rcts with long-term functional outcomes. PMID: 32207131 [PubMed - in process]
Source: Tijdschrift voor Psychiatrie - Category: Psychiatry Authors: Tags: Tijdschr Psychiatr Source Type: research
In this study, we show that calorie restriction is protective against age-related increases in senescence and microglia activation and pro-inflammatory cytokine expression in an animal model of aging. Further, these protective effects mitigated age-related decline in neuroblast and neuronal production, and enhanced olfactory memory performance, a behavioral index of neurogenesis in the SVZ. Our results support the concept that calorie restriction might be an effective anti-aging intervention in the context of healthy brain aging. Greater Modest Activity in Late Life Correlates with Lower Incidence of Dementia ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
You're reading A Wee Wiggle in my Journey to Family, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. Many of us have faced depression, struggled with low self-esteem, and other debilitating mental health challenges. My own journey with depression was a result of growing up with a rare blood disorder and being told I could never have children of my own. This completely changed my dreams of what family and life meant. Years later I suffered with a rare soft tissue sarcoma, yet, baffling the best of doctors, I survived. I&rs...
Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: depression featured psychology self improvement best books Donna Grant Wilcox faith family mental health pickthebrain Source Type: blogs
00:00 to 02.26—Dr. Bihari gives his background and credentials. Dr. Bihari: My medical training started at Harvard Medical School. I graduated in 1957. Then I trained in Internal Medicine at one of the Harvard teaching hospitals in Boston, Beth Israel, and then in Neurology at Massachusetts General in Boston. Then I went to the National Institutes of Health for two years doing brain physiology—brain research. I did another residency training in Psychiatry in New York, at Columbia Presbyterian Medical Center and then, over the following five or six years, I got very involved in working in Drug Addiction. By 197...
Source: HONEST MEDICINE: My Dream for the Future - Category: Consumer Health News Authors: Tags: Anecdotal Treatments HONEST MEDICINE Integrative Medicine Low Dose Naltrexone Obituaries Source Type: blogs
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