Liberia: Leprosy Victims Complain of Neglect
[NEWS] Sufferers of the Leprosy disease who are residing at the Suakoko Leprosy School in Bong County say they have been neglected by the Liberian government.
In conclusion, this review reported that IL-37 has a crucial role in reducing infection-associated inflammation and has a good impact on inflammation-induced pathology. However, tight regulation that achieved balance between effector immune responses that required for pathogen elimination and limited tissue damage that resulted from excessive inflammation should be existed in the potential IL-37 therapy to prevent clinical complications of a disease. PMID: 31633447 [PubMed - as supplied by publisher]
Abstract In Type II lepromatous reaction, there is exacerbation of humoral immunity, classified as Gell &Coombs Type III hypersensitivity reaction. It is more common in lepromatous borderline (LB) and lepromatous lepromatous (LL) patients. Our objective was to study the clinical and laboratorial expressions of lepromatous Type II reactions, establishing concordances between them, and for this the medical records of leprosy patients observed at the Clementino Fraga Filho University Hospital of the Federal University of Rio de Janeiro (HUCFF/UFRJ) were reviewed. There were a total of 358 leprosy cases over a per...
Publication date: 19–25 October 2019Source: The Lancet, Volume 394, Issue 10207Author(s): Pugazhenthan Thangaraju, Sajitha Venkatesan
In Reply We thank Dr Bishnoi and colleagues for their interest in our study and for sharing us with the current epidemic status of leprosy and the focus of the disease control activities in India.
To the Editor We congratulate Liu et al for their work involving proactive HLA screening to prevent dapsone hypersensitivity syndrome (DHS) in patients with leprosy. Herein, we describe the practical difficulties in translating this screening into clinical practice in India.
In this study, the inflammation noted in lesions of T1R is a different phenotype of Th17 which produce double positive IL-17A+IL17F+ and also contributes IL-17 producing neutrophils and thus would be useful for monitoring, diagnosis and treatment response before reactions episodes. PMID: 31629113 [PubMed - as supplied by publisher]
PMID: 31621065 [PubMed - as supplied by publisher]
C, Ramos AN Abstract The study aimed to analyze the magnitude and sociodemographic profile of leprosy cases linked to household contact networks with overlapping of the disease in two Brazilian municipalities (counties), one in the North and the other in the Northeast, from 2001 to 2014. This was a cross-sectional, descriptive, analytical study based on primary and secondary data from new leprosy cases in Picos, Piauí State, and Rolim de Moura, Rondônia State. "Overlapping" was defined as new cases with the occurrence of at least one more leprosy case in the individual's household contact ne...