Africa: Malaria Vaccine Trial Raises Hopes

[Global Fund] Geneva -Gavi, the Vaccine Alliance and the Global Fund to Fight AIDS, Tuberculosis and Malaria welcome the results of a large-scale trial of a malaria vaccine candidate in sub-Saharan Africa.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news

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A 25 year-old tuberculosis patient is treated at her home in Funafuti, the main island of Tuvalu in the South Pacific. Credit: UNDP Tuvalu/Aurélia Rusek.By External SourceUNITED NATIONS, Oct 17 2019 (IPS) A staggering 1.5 million people died from tuberculosis (TB) last year, the UN health agency said on Thursday, in an appeal for far greater funding and political support to eradicate the curable and preventable disease. Caused by the bacteria Mycobacterium tuberculosis, TB commonly causes persistent coughing, fatigue and weight loss. According to the World Health Organization (WHO) and its latest Global TB Report, a...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Global Headlines Health Poverty & SDGs Source Type: news
In conclusion, he pointed to the “profound” challenges we face, saying: “I am confident that if we continue and strengthen international co-operation and seize the opportunities already available, while creating even more opportunities, we can overcome them – together”.   ‘A political choice’ Universal health coverage means all people regardless of their ability to pay, having access to the health care they need, when and where they need it, without facing financial hardship. Congratulating world leaders, Tedros Adhanom Ghebreyesus, Director-General at the World Health Or...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Development & Aid Global Headlines Health Human Rights Source Type: news
Conclusions Toxoplasma gondii infection induces a strong innate and adaptive immune response. While the innate immunity is important for controlling the early stages of the infection (Yarovinsky, 2014), the adaptive immunity is critical for restricting the parasite replication during the later stages (Gazzinelli et al., 1992). Amongst the adaptive immune subsets, CD8 T cells are the primary effector cells while CD4 T cells play an essential helper role to maintain long-term immunity (Casciotti et al., 2002). Notwithstanding, a robust CD8 T cell immunity induced during acute phase of infection, does not result in the total...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Despite the vaccine ’ s drawbacks, the W.H.O. endorsed testing on 360,000 children, in an effort to lower death rates in Africa.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Vaccination and Immunization Malaria Mosquitoes Clinical Trials GlaxoSmithKline PLC Gavi, the Vaccine Alliance Global Fund to Fight AIDS, Tuberculosis and Malaria Sanaria Inc World Health Organization Unitaid Africa Equatorial Guinea Source Type: news
Jeffrey G. Shaffer1*, Frances J. Mather1, Mamadou Wele2, Jian Li1, Cheick Oumar Tangara2, Yaya Kassogue2, Sudesh K. Srivastav1, Oumar Thiero2, Mahamadou Diakite2, Modibo Sangare2, Djeneba Dabitao2, Mahamoudou Toure2, Abdoulaye A. Djimde2, Sekou Traore2, Brehima Diakite2, Mamadou B. Coulibaly2, Yaozhong Liu1, Michelle Lacey3, John J. Lefante1, Ousmane Koita2, John S. Schieffelin4, Donald J. Krogstad1 and Seydou O. Doumbia2 1Department of Global Biostatistics and Data Science, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, United States 2Faculty of Medicine and Odontostomatology, Un...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
ConclusionThe most advanced phase III clinical applications led to the development of two vaccines containing QS-21 as part of AS, the Herpes Zoster vaccine (HZ/su) (ShingrixTM) which received a license in 2017 from the FDA and a marketing authorization in EU in 2018 and the RTS,S/AS01 vaccine (MosquirixTM) against malaria which was approved by the EMA in 2015 for further implementation in Sub Saharan countries for routine use.Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
(CNN) — From climate change to superbugs, the World Health Organization has laid out 10 big threats to our global health in 2019. And unless these threats get addressed, millions of lives will be in jeopardy. Here’s a snapshot of 10 urgent health issues, according to the United Nations’ public health agency: Not vaccinating when you can One of the most controversial recent health topics in the US is now an international concern. “Vaccine hesitancy — the reluctance or refusal to vaccinate despite the availability of vaccines — threatens to reverse progress made in tackling vaccine-prevent...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News CNN Local TV Source Type: news
There’s a very big difference between simple and easy—especially when it comes to global health. It’s simple to eradicate polio—just get all children are vaccinated. It’s simple to reduce nighttime malaria infections—make sure everyone in malaria-endemic areas sleeps under a bed net. But none of that is easy. The tension between simple and easy is at play when it comes to eradicating poverty in the developing world too, as the Bill &Melinda Gates Foundation makes clear in its second annual Goalkeepers Data Report. In a conversation with TIME, Bill Gates points to two recent waves of ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized onetime public health Source Type: news
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 009 The diagnosis of HIV is no longer fatal and the term AIDS is becoming less frequent. In many countries, people with HIV are living longer than those with diabetes. This post will hopefully teach the basics of a complex disease and demystify some of the potential diseases you need to consider in those who are severely immunosuppressed. While trying to be comprehensive this post can not be exhaustive (as you can imagine any patient with ...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Clinical Cases Tropical Medicine AIDS art cryptococcoma cryptococcus HIV HIV1 HIV2 PEP PrEP TB toxoplasma tuberculoma Source Type: blogs
20 years ago, infectious diseases dominated the global health agenda. Policy makers, researchers, implementers, and donors united in the fight against infectious diseases, creating the Millennium Development Goals, the Global Fund to Fight AIDS, Tuberculosis and Malaria, Gavi, the Vaccine Alliance, the US President's Emergency Plan For AIDS Relief (PEPFAR), the Roll Back Malaria Partnership, the Multilateral Initiative on Malaria (MIM),1 and more. Tremendous progress was made. Malaria benefited spectacularly and there has been a 47% reduction in global deaths from the disease since 2000.
Source: LANCET - Category: General Medicine Authors: Tags: Comment Source Type: research
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