Diet and EBV infection

American research has found that people with a bad diet or who ate beans, red meat and fruit juice daily had a higher risk of being infected by the virus that can cause glandular fever. Newswise Epstein Barr virus (EBV) - A to Z of MS
Source: Multiple Sclerosis Trust - Category: Neurology Source Type: news

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Shanshan Zhang1, Dongli Yuan2 and Ge Tan1* 1Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China 2The Institute of Medical Information, Chongqing Medical University, Chongqing, China Primary systemic vasculitis can affect every structure in both the central and peripheral nervous system, causing varied neurological manifestations of neurological dysfunction. Early recognition of the underlying causes of the neurological symptoms can facilitate timely treatment and improve the prognosis. This review highlights the clinical manifestations of primary systemic vasc...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusions In conclusion, articles in this Research Topic made a very significant contribution to our understanding of the role played by environmental factors, dysbiotic conditions, and infections in triggering diseases. Since this is a rapidly expanding area of research, many other factors contributing to the onset of these diseases are not covered here. We are confident, however, that further studies will expand the list as well as bring a better understanding of mechanisms involved in the onset of autoimmune and autoinflammatory diseases. Author Contributions All authors listed have made a substantial, direct and i...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
The suspected link between glandular fever – mono – and multiple sclerosis has grown stronger after a trial found that treating the virus improves MS symptoms
Source: New Scientist - Health - Category: Consumer Health News Source Type: research
Authors: Cohen JI Abstract Epstein-Barr virus (EBV) is the primary cause of infectious mononucleosis and is associated with several malignancies, including nasopharyngeal carcinoma, gastric carcinoma, Hodgkin lymphoma, Burkitt lymphoma, and lymphomas in immunocompromised persons, as well as multiple sclerosis. A vaccine is currently unavailable. While monomeric EBV gp350 was shown in a phase 2 trial to reduce the incidence of infectious mononucleosis, but not the rate of EBV infection, newer formulations of gp350 including multimeric forms, viruslike particles, and nanoparticles may be more effective. A vaccine tha...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Authors: Alonso-Padilla J, Lafuente EM, Reche PA Abstract Epstein-Barr virus is a very common human virus that infects 90% of human adults. EBV replicates in epithelial and B cells and causes infectious mononucleosis. EBV infection is also linked to various cancers, including Burkitt's lymphoma and nasopharyngeal carcinomas, and autoimmune diseases such as multiple sclerosis. Currently, there are no effective drugs or vaccines to treat or prevent EBV infection. Herein, we applied a computer-aided strategy to design a prophylactic epitope vaccine ensemble from experimentally defined T and B cell epitopes. Such strat...
Source: Journal of Immunology Research - Category: Allergy & Immunology Tags: J Immunol Res Source Type: research
AbstractDespite extensive studies focusing on the changes in expression of microRNAs (miRNAs) in multiple sclerosis (MS) compared to healthy controls, few studies have evaluated the association of genetic variants of miRNAs with MS clinical course. We investigated whether a functional polymorphism in the MS associatedmiR-146a gene predicted clinical course (hazard of conversion to MS and of relapse, and annualized change in disability), using a longitudinal cohort study of persons with a first demyelinating event followed up to their 5-year review. We found the genotype (GC+CC) of rs2910164 predicted relapse compared with ...
Source: Neurological Sciences - Category: Neurology Source Type: research
High levels of a serum marker of Epstein-Barr virus (EBV) infection and a history of infectious mononucleosis are associated with an increased risk of multiple sclerosis (MS) across racial and ethnic groups, new research shows.Reuters Health Information
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
Past infection with the Epstein-Barr virus (EBV) and a history of glandular fever (infectious mononucleosis) are associated with an increased risk of multiple sclerosis (MS) across multiple ethnic groups, research has found.
Source: The Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system. MS likely results from a complex interplay between predisposing causal gene variants (the strongest influence coming from HLA class II locus) and environmental risk factors such as smoking, infectious mononucleosis, and lack of sun exposure/vitamin D. However, little is known about the mechanisms underlying MS development and progression. Moreover, the clinical heterogeneity and variable response to treatment represent additional challenges to a comprehensive understanding and efficient treatment of disease. Epigeneti...
Source: Physiological Genomics - Category: Genetics & Stem Cells Authors: Tags: Review Source Type: research
Latest study shows blacks and Hispanics also vulnerable Source: HealthDay Related MedlinePlus Pages: Infectious Mononucleosis, Multiple Sclerosis
Source: MedlinePlus Health News - Category: Consumer Health News Source Type: news
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