What is in the Differential Diagnosis for Black and White Skin Conditions?
Discussion This is the third in a short case series of differential diagnoses of colored skin conditions. An introduction to dermatological terminologies and information about colors can be can be found here. A differential diagnosis by distribution and common pattern can be found here. For red, orange and yellow conditions, a review can be found here. For green, blue and purple conditions, a review can be found here. For brown and grey conditions, a review can be found here. Note that any color can be a normal variant for an individual or is physiologic for a given state. When lesions of the opposite color of the normal s...
Source: PediatricEducation.org - May 9, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

How does Lichen Sclerosus et Atrophicus Present?
Discussion Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory disease with a strong autoimmune association. It can occur with other autoimmune diseases. Its specific cause is unknown. It affects females and males of all ages, but especially females 40-60 years. In the pediatric population it affects prepubertal females most often. Treatment includes steroid medications or anti-inflammatory medications. Other treatments may be offered including phototherapy, and much less commonly systemic steroids or immunosuppressive therapy. Circumcision may also be an option for some males. Childhood LSA generally improves b...
Source: PediatricEducation.org - September 6, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

The safety of medicinal plants used in the treatment of vitiligo and hypermelanosis: a systematic review of use and reports of harm - Hussain I.
INTRODUCTION: Vitiligo is disfiguring and devastating condition that can humans feel stigmatic and devalued. Melasma is a general condition of hyperpigmentation particularly involving the face. The pigmentation disorders of vitiligo (hypopigmentation or de... (Source: SafetyLit)
Source: SafetyLit - April 5, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

What Are the Oral Equivalents of Milia of the Face?
Discussion Milia are small, usually < or = to 3 mm, benign, white, superficial keratinous cysts. They can arise spontaneously (are defined as primary) or because of other conditions (are defined as secondary). Milia can occur at any age but are common in adult patients. However, primary care providers for neonates see it commonly as well as congenital milia occurs in 40-50% of newborns. Milia occurs more often on the face (especially the nose), but also scalp, neck/upper parts of the trunk and upper extremities. They usually resolve spontaneously in a few weeks, but patient and parent preference may dictate treatment. T...
Source: PediatricEducation.org - November 9, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

What Causes Neutropenia?
Discussion Neuropenia is defined as a neutrophil count < 1500/µL. It is classified as mild from 1000-1500/µL, moderate from 500-1000/µL, and severe if < 500/µL. It is not uncommonly seen in the setting of acute self-limited infections, and with re-testing returns to normal. It is also not uncommon at certain ages, such as perinatally, especially in premature infants (up to 6%) . It is also common in certain ethnic groups particularly African American or Arabic populations where up to 10% of the children may have mild neutropenia which does not cause clinical disease. The overall prevalence a...
Source: PediatricEducation.org - March 2, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

What Causes Hyperpigmentation?
Discussion Skin color is primarily due to genetic factors. Melanocytes are usually found in skin in the basal layer of the epidermis which is also where the melanin usually lies. There are a range of normal skin phenotypes that have been described by Fitzpatrick and range from I-VI: I – pale white skin, blond hair, blue eyed, does not tan, always burns II – fair skin, blue eyed, tans poorly, burns easily III – darker white skin, burns initially then tans IV – light brown skin, tans easily, burns minimally V – brown skin, tans darkly easily, burns rarely VI – dark brown skin, alway...
Source: PediatricEducation.org - December 17, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

What Causes Post-Inflammatory Hypopigmentation?
Discussion Hypopigmentation can be worrisome for many families because of cosmesis and the worry that “something is wrong.” The normal natural changes in skin-tone over the year due to different light exposure and wide variations within individuals is not something that many people are aware of. Post-inflammatory hypopigmentation is a common cause of hypopigmentation. Vitiligo is the most common cause of depigmentation. Vitiligo is an acquired, depigmenting disorder with typical lesions appearing as milky white macules with distinct margins that are not scaly. Hair (including eyebrows and eyelashes) can be dep...
Source: PediatricEducation.org - November 12, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Medical News Today: What is hypopigmentation?
In this article, learn about the different types of hypopigmentation, including albinism and vitiligo, as well as why these conditions occur. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 4, 2017 Category: Consumer Health News Tags: Dermatology Source Type: news

Genetics Underlying Rare Syndrome Identified Genetics Underlying Rare Syndrome Identified
Deafness, blindness, albinism, and dense bones resulted from inheriting two recessive mutations in a gene already implicated in two dominant conditions of deafness and hypopigmentation.Medscape Medical News (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - February 28, 2017 Category: Infectious Diseases Tags: Internal Medicine News Source Type: news

Depigmentation Cases Prompt New Label Warning for ADHD Patch
After dozens of reports of skin depigmentation or hypopigmentation associated with use of the methylphenidate transdermal system marketed as Daytrana, FDA officials are requiring that a new warning be added to the medication's package label. (Source: AAFP News)
Source: AAFP News - June 26, 2015 Category: Primary Care Source Type: news

Liberia: Liberian Albinos Get Free Preventative Skin Cancer Treatment
[VOA]More than 300 albinos in Liberia have received free treatment for skin cancer prevention as part of a new government initiative. The U.S.-based National Organization for Albinism and Hypopigmentation says that albinos living in tropical regions, such as West Africa, are at increased risk of developing skin cancer. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - June 26, 2013 Category: African Health Source Type: news

Infectious Diseases: Images in Clinical Medicine
Editor: V. Dimov, M.D., Cleveland ClinicHypoglossal Nerve Palsy during Meningococcal Meningitis. NEJM, 10/2014.Herpes Zoster Involving the S1 Dermatome. NEJM, 05/2014.Tinea Faciei. NEJM, 05/2014.Disseminated Cryptococcosis in a CLL patient. 05/2014.Scrofuloderma due to Mycobacterium tuberculosis. NEJM, 06/2012.Leonine Facies in Lepromatous Leprosy. NEJM, 04/2012.Intestinal Infestation with Ancylostoma ceylanicum. NEJM, 03/2012.Kerion celsi form of tinea capitis caused by a T-cell hypersensitivity reaction. NEJM, 03/2012.Eye can see a nest of worms! Thelazia callipaeda. Lancet, 03/2012.Madura Foot. NEJM, 01/2012.Paragonimia...
Source: Clinical Cases and Images - August 22, 2009 Category: General Medicine Tags: Images Infectious Diseases Source Type: news